Results 51 to 60 of about 86,531 (200)
Molecular and Cellular Biology, 2016 The role of AMP-activated protein kinase (AMPK) in promoting fatty acid (FA) oxidation in various tissues, such as liver and muscle, has been well understood.
Sun-Joong Kim +5 more
semanticscholar +1 more source
Cell Death and Disease, 2023 Epigenetic mechanisms involved in gene expression play an essential role in various cellular processes, including lipid metabolism. Lysine acetyltransferase 8 (KAT8), a histone acetyltransferase, has been reported to mediate de novo lipogenesis by ...
Bingquan Qiu +12 more
doaj +1 more source
Potential of Traditional Medicinal Plants for Treating Obesity: A Review [PDF]
2012 International Conference on Nutrition and Food Sciences,
IPCBEE vol. 39 (2012) IACSIT Press, Singapore, 2012 Obesity is a global health concern associated with high morbidity and mortality. Therapeutic strategies include synthetic drugs and surgery, which may entail high costs and serious complications. Plant-based medicinal agents offer an alternative approach.
arxiv
Cell-intrinsic lysosomal lipolysis is essential for macrophage alternative activation
Nature Immunology, 2014 Alternative (M2) activation of macrophages driven via the α-chain of the receptor for interleukin 4 (IL-4Rα) is important for immunity to parasites, wound healing, the prevention of atherosclerosis and metabolic homeostasis.
S. C. Huang +16 more
semanticscholar +1 more source
The Subtle Balance between Lipolysis and Lipogenesis: A Critical Point in Metabolic Homeostasis
Nutrients, 2015 Excessive accumulation of lipids can lead to lipotoxicity, cell dysfunction and alteration in metabolic pathways, both in adipose tissue and peripheral organs, like liver, heart, pancreas and muscle.
C. Saponaro +3 more
semanticscholar +1 more source
Suppression of adipose lipolysis by long-chain fatty acid analogs
Journal of Lipid Research, 2012 Agonist-induced lipolysis of adipose fat is robustly inhibited by insulin or by feedback inhibition by the long-chain fatty acids (LCFA) produced during lipolysis. However, the mode of action of LCFA in suppressing adipose lipolysis is not clear.
Bella Kalderon +5 more
doaj
Animal Nutrition, 2023 Docosahexaenoic acid (DHA) is a biologically active fatty acid that reduces the accumulation of lipids. However, the molecular mechanism underlying this process, particularly in fish, is not well understood. Recent studies show that endoplasmic reticulum
Xiaocheng Huang +4 more
doaj
Lipolysis: cellular mechanisms for lipid mobilization from fat stores
Nature Metabolism, 2021 Gernot F. Grabner +3 more
semanticscholar +1 more source
Relationship between cyclic AMP production and lipolysis induced by forskolin in rat fat cells.
Journal of Lipid Research, 1992 Forskolin (7 beta-acetoxy-8, 13-epoxy-1 alpha,6 beta,9 alpha-trihydroxy-labd-14-ene-11-one) induced both cyclic AMP production and lipolysis in intact fat cells, but stimulated lipolysis without increasing cyclic AMP at a concentration of 10(-5) M ...
H Okuda, C Morimoto, T Tsujita
doaj
Growth hormone acts along the PPARγ-FSP27 axis to stimulate lipolysis in human adipocytes.
American Journal of Physiology. Endocrinology and Metabolism, 2019 The lipolytic effects of growth hormone (GH) have been known for half a century and play an important physiological role for substrate metabolism during fasting.
V. Sharma +12 more
semanticscholar +1 more source