Results 101 to 110 of about 38,790 (251)
Neuraminidase-activated microglia compromise the viability of ependymocytes [PDF]
, 2017 Neuraminidase (NA) is a sialidase present in the envelope/wall of some virus/bacteria responsible for brain infections, such as flu, mumps or meningitis. The intracerebroventricular injection of NA in the rat brain provokes ependymal detachment and death,
Carrillo-Pinzon, Cristobal +4 more
core
Potential Use of Microbial Surfactant in Microemulsion Drug Delivery System: A Systematic Review
Drug Design, Development and Therapy, 2020 Mandana Ohadi,1 Arash Shahravan,2 Negar Dehghannoudeh,3 Touba Eslaminejad,1 Ibrahim M Banat,4 Gholamreza Dehghannoudeh1,5 1Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran; 2Endodontology ...
Ohadi M +5 more
doaj
Microbiology Indonesia, 2015 Surfactin is a lipopeptide biosurfactant that show potential biomedical application due to its activities such as antiviral, antibacterial, antifungi, anticancer, and antimycoplasma. Bacillus amyloliquefaciens MD4-12, isolated from oil-contaminated soil,
AHMAD WIBISANA +3 more
doaj +1 more source
Targeted anion transporter delivery by coiled-coil driven membrane fusion [PDF]
, 2016 Synthetic anion transporters (anionophores) have potential as biomedical research tools and therapeutics. However, the efficient and specific delivery of these highly lipophilic molecules to a target cell membrane is non-trivial. Here, we investigate the
Bahreman, Azadeh +7 more
core +3 more sources
Lipopeptides: Biosynthesis and Applications [PDF]
Journal of Microbial & Biochemical Technology, 2015 Microbial surfactants are amphiphilic molecules. They possess a strong tendency to reduce the interfacial tension among compounds. Biosurfactants possess diverse chemical structures and are nontoxic and hence are biodegradable. They have many applications in bioremediation, enhanced oil recovery, pharmaceutical and in food industry.
openaire +1 more source
The interplay between daptomycin and the immune system
Frontiers in Immunology, 2014 Antibiotics may have bacteriostatic or bactericidal effects but may also cause immunomodulation. Lipopeptides are known immunomodulators that interact with pattern recognition receptors (PRRs) such as Toll-like receptors (TLRs) in antigen presenting ...
Theodoros eKelesidis
doaj +1 more source
Pharmacological Researchβ-arrestins play pivotal roles in seven transmembrane receptor (7TMR) signalling and trafficking. To study their functional role in regulating specific receptor systems, current research relies mainly on genetic tools, as few pharmacological options are ...
Rebecca L. Brouillette +11 more
doaj +1 more source
Non-leaching antimicrobial surfaces through polydopamine bio-inspired coating of quaternary ammonium salts or an ultrashort antimicrobial lipopeptide. [PDF]
, 2012 Bacterial fouling on surfaces significantly increases the resistance of bacteria toward antibiotics, which leads to medical complications and a corresponding financial burden.
Bauer, Michael +4 more
core +1 more source
Structure of the lipopeptide antibiotic tsushimycin
Acta Crystallographica Section D Biological Crystallography, 2005 The amphomycin derivative tsushimycin has been crystallized and its structure determined at 1.0 A resolution. The asymmetric unit contains 12 molecules and with 1300 independent atoms this structure is one of the largest solved using ab initio direct methods.
Bunkoczi, G. +2 more
openaire +3 more sources
Frontiers in Pharmacology, 2014 We have previously discovered a synergistically therapeutic combination of two Toll-like receptor (TLR) ligands, an oligodeoxynucleotide (ODN) and Pam2CSK4.
Victoria eAlfaro +11 more
doaj +1 more source