Results 31 to 40 of about 6,907 (199)
ATGL Promotes Autophagy/Lipophagy via SIRT1 to Control Hepatic Lipid Droplet Catabolism
Cell Reports, 2017 Hepatic lipid droplet (LD) catabolism is thought to occur via cytosolic lipases such as adipose triglyceride lipase (ATGL) or through autophagy of LDs, a process known as lipophagy.
Aishwarya Sathyanarayan +2 more
doaj +1 more source
Quercetin enhances fatty acid β-oxidation by inducing lipophagy in AML12 hepatocytes
Heliyon, 2021 Recent evidence demonstrated that chronic intake of quercetin attenuated hepatic fat accumulation in various animal models of obesity and diabetes. However, whether quercetin has the ability to enhance energy metabolism in hepatocytes and its exact ...
Misato Fukaya +5 more
doaj +1 more source
Lipid storage and autophagy in melanoma cancer cells [PDF]
, 2017 Cancer stem cells (CSC) represent a key cellular subpopulation controlling biological features such as cancer progression in all cancer types. By using melanospheres established from human melanoma patients, we compared less differentiated melanosphere ...
Cordella, Martina +9 more
core +2 more sources
Macrophage autophagy in atherosclerosis [PDF]
, 2013 Macrophages play crucial roles in atherosclerotic immune responses. Recent investigation into macrophage autophagy (AP) in atherosclerosis has demonstrated a novel pathway through which these cells contribute to vascular inflammation.
Carnuccio, R. +5 more
core +2 more sources
Cell Death and Disease, 2021 Autophagy-mediated lipotoxicity plays a critical role in the progression of diabetic nephropathy (DN), but the precise mechanism is not fully understood. Whether lipophagy, a selective type of autophagy participates in renal ectopic lipid deposition (ELD)
Yachun Han +11 more
doaj +1 more source
Molecular Events Occurring in Lipophagy and Its Regulation in Flaviviridae Infection
Frontiers in Microbiology, 2021 Diseases caused by Flaviviridae have a wide global and economic impact due to high morbidity and mortality. Flaviviridae infection usually leads to severe, acute or chronic diseases, such as liver injury and liver cancer resulting from hepatitis C virus (
Keke Wu +19 more
doaj +1 more source
eLife, 2017 Dietary restriction increases the longevity of many organisms, but the cell signaling and organellar mechanisms underlying this capability are unclear. We demonstrate that to permit long-term survival in response to sudden glucose depletion, yeast cells ...
Arnold Y Seo +7 more
doaj +1 more source
The selectivity and specificity of autophagy in drosophila [PDF]
, 2012 Autophagy is a process of cellular self-degradation and is a major pathway for elimination of cytoplasmic material by the lysosomes. Autophagy is responsible for the degradation of damaged organelles and protein aggregates and therefore plays a ...
Chou +27 more
core +2 more sources
Microbiology Spectrum, 2023 During yeast stationary phase, a single spherical vacuole (lysosome) is created by the fusion of several small ones. Moreover, the vacuolar membrane is reconstructed into two distinct microdomains.
Fan Qiu +7 more
doaj +1 more source
Lipid droplet-organelle interactions: emerging roles in lipid metabolism. [PDF]
, 2015 Cellular homeostasis depends on the precisely coordinated use of lipids as fuels for energy production, building blocks for membrane biogenesis or chemical signals for intra-cellular and inter-cellular communication.
Barbosa, Antonio Daniel +2 more
core +2 more sources