Results 81 to 90 of about 6,907 (199)

Sphingolipids as emerging mediators in retina degeneration [PDF]

open access: yes, 2019
The sphingolipids ceramide (Cer), sphingosine-1-phosphate (S1P), sphingosine (Sph), and ceramide-1-phosphate (C1P) are key signaling molecules that regulate major cellular functions.
Prado Spalm, Facundo Heber   +3 more
core   +1 more source

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

open access: yesAdvanced Science, Volume 13, Issue 9, 13 February 2026.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta   +14 more
wiley   +1 more source

Ethanol-triggered Lipophagy Requires SQSTM1 in AML12 Hepatic Cells [PDF]

open access: yesScientific Reports, 2017
AbstractEthanol-induced hepatic lipophagy plays an important cytoprotective role against liver injury, but its mechanism is not fully determined. In the present study, ethanol-induced lipophagy was studied in an immortalized mouse hepatocyte line, AML12.
Wang, Lin   +5 more
openaire   +2 more sources

CD36 plays a negative role in the regulation of lipophagy in hepatocytes through an AMPK-dependent pathway[S]

open access: yesJournal of Lipid Research, 2019
Fatty acid translocase cluster of differentiation (CD36) is a multifunctional membrane protein that facilitates the uptake of long-chain fatty acids. Lipophagy is autophagic degradation of lipid droplets.
Yun Li   +10 more
doaj   +1 more source

Role of autophagy in the control of food intake [PDF]

open access: yes, 2015
Treballs Finals de Grau de Farmàcia, Facultat de Farmàcia, Universitat de Barcelona, 2015. Tutora: Dolors Serra i Cucurull.[eng] Autophagy is an intracellular pathway which has been well characterised since many years ago. It is present in all cell types
Balañá García-Vela, Blanca
core  

Lipid partitioning at the nuclear envelope controls membrane biogenesis. [PDF]

open access: yes, 2015
Partitioning of lipid precursors between membranes and storage is crucial for cell growth, and its disruption underlies pathologies such as cancer, obesity, and type 2 diabetes.
Abreu, Susana   +6 more
core   +3 more sources

A Supramolecular Nanoscavengers: Based “Cargo‐Exchange” Breaking Cholesterol Metabolic Dysregulation for Glioblastoma Therapy

open access: yesAdvanced Science, Volume 13, Issue 7, 3 February 2026.
Dysregulated cholesterol metabolism, driven by a complex array of mechanisms, is a defining characteristic of glioblastoma (GBM). In this study, supramolecular nanoscavengers are engineered by harnessing the intrinsic binding affinity between endogenous small‐molecule cholesterol and β‐cyclodextrin (β‐CD).
Zonghua Tian   +7 more
wiley   +1 more source

Expanded genetic screening in Caenorhabditis elegans identifies new regulators and an inhibitory role for NAD+ in axon regeneration. [PDF]

open access: yes, 2018
The mechanisms underlying axon regeneration in mature neurons are relevant to the understanding of normal nervous system maintenance and for developing therapeutic strategies for injury.
Andrusiak, Matthew G   +10 more
core   +1 more source

Truncal Acne: Pathophysiology, Clinical Features, and Management Strategies

open access: yesJournal of Cosmetic Dermatology, Volume 25, Issue 2, February 2026.
ABSTRACT Background Truncal acne is common but underrecognized. Its pathogenesis is often considered similar to facial acne, so most studies and guidelines focus on facial involvement despite the substantial disease burden of truncal lesions. Objective This narrative review compares structural and physiological differences between truncal and facial ...
Xiaoyue Feng, Yong Chen, Youting Liu
wiley   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, Volume 600, Issue 2, Page 140-163, January 2026.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

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