Results 201 to 210 of about 24,091 (241)

Nanostructured Deep Eutectic Systems in Healthcare: From Bioactive Solvents to Intelligent Biointerfaces, Wearables, and AI‐Driven Design

Advanced NanoBiomed Research, EarlyView.
Beyond the green solvent paradigm, this review redefines Deep Eutectic Systems (DES) as programmable supramolecular nanoassemblies. We survey their biomedical convergence: stabilizing thermolabile mRNA to enable cold chain‐free logistics, reshaping transdermal microneedle delivery, enabling long‐term wearables via eutectogels, and utilizing Generative ...
Jeesu Moon, Min Seo Kim, Jae‐Seung Lee
wiley   +1 more source

Molecular Insights of Cholestasis in MDR2 Knockout Murine Liver Organoids. [PDF]

J Proteome Res
Blázquez-García I, Guerrero L, Cacho-Navas C, Djouder N, Millan J, Paradela A, Carmona-Rodríguez L, Corrales FJ.   +7 more
europepmc   +1 more source

Chronotoxici-Plate Containing Droplet-Engineered Rhythmic Liver Organoids for Drug Toxicity Evaluation. [PDF]

Adv Sci (Weinh)
Zhou J, Huang YC, Wang W, Li J, Hou Y, Yi Z, Yang H, Hu K, Zhu Y, Wang Z, Ma S.   +10 more
europepmc   +1 more source

A Practical Gut‐On‐Chip Workflow for Imaging‐Based Assessment of Epithelial Barrier Dynamics During E. coli Co‐Culture

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The intestinal epithelium and its resident microbiota form a dynamic interface that is central to gut homeostasis, but this interface is difficult to model with conventional tools. Static Transwell cultures lack physiological fluid shear, whereas animal models are costly and poorly suited to quantitative, high‐content imaging.
Shih‐Wei Chiang, Chuan‐Yi Yang, Guan‐Yu Chen   +2 more
wiley   +1 more source

Development of an alcoholic liver disease model for drug evaluation from human induced pluripotent stem cell-derived liver organoids. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Feng Z, Zhou B, Shuai Q, Wei Y, Jin N, Wang X, Zhao H, Liu Z, Xu J, Mu J, Xie J.   +10 more
europepmc   +1 more source

Generation of Multicellular 3D Liver Organoids From Induced Pluripotent Stem Cells as a Tool for Modelling Liver Diseases. [PDF]

Bio Protoc
Maepa SW, Marakalala MJ, Ndlovu H.
europepmc   +1 more source

Reproducible generation of human liver organoids (HLOs) on a pillar plate platform via microarray 3D bioprinting. [PDF]

Lab Chip
Shrestha S, Lekkala VKR, Acharya P, Kang SY, Vanga MG, Lee MY.   +5 more
europepmc   +1 more source

Establishment and characterization of turtle liver organoids provides a potential model to decode their unique adaptations. [PDF]

Commun Biol
Zdyrski C, Gabriel V, Gessler TB, Ralston A, Sifuentes-Romero I, Kundu D, Honold S, Wickham H, Topping NE, Sahoo DK, Bista B, Tamplin J, Ospina O, Piñeyro P, Arriaga M, Galan JA, Meyerholz DK, Allenspach K, Mochel JP, Valenzuela N.   +19 more
europepmc   +1 more source

Novel hepatocyte-like liver organoids recapitulate crucial mature hepatic functions

Ardisasmita AI, Joore IP, Levy N, Myszczyszyn A, Marsee A, Sinnige T, Ruiter J, Ferdinandusse S, Dudaryeva O, Gruber E, Daive V, Levato R, Spee B, Verstegen M, van der Laan L, Nieuwenhuis EES, Schene IF, Fuchs SA.   +17 more
europepmc   +1 more source

Liver Organoids: Recent Developments, Limitations and Potential [PDF]

Frontiers in Medicine, 2021
Liver cell types derived from induced pluripotent stem cells (iPSCs) share the potential to investigate development, toxicity, as well as genetic and infectious disease in ways currently limited by the availability of primary tissue. With the added advantage of patient specificity, which can play a role in all of these areas.
Gareth Sullivan, Sean Philip Harrison, Alexandr Dejneka   +2 more
exaly   +6 more sources