Results 21 to 30 of about 7,849 (242)
Effects of Mass Change on Liquid–Liquid Phase Separation of the RNA-Binding Protein Fused in Sarcoma
Biomolecules, 2023 In recent years, many experimental and theoretical studies of protein liquid–liquid phase separation (LLPS) have shown its important role in the processes of physiology and pathology.
Weiqian Dong +4 more
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Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design [PDF]
Advanced scienceThis review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Zhu J +5 more
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International Journal For Multidisciplinary Research, 2023 Allergic rhinitis, an inflammatory immune response to airborne allergens affecting the nasal mucosa, can cause distressing symptoms and disrupt daily life. It often coexists with asthma and lacks an effective conventional treatment. This study explores the successful Ayurvedic treatment of a 51-year-old female patient with perennial allergic rhinitis ...
Ranjana Kaushal -, Deeksha Sharma -
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Abnormal phase separation of biomacromolecules in human diseases
Acta Biochimica et Biophysica Sinica, 2023 Membrane-less organelles (MLOs) formed through liquid-liquid phase separation (LLPS) are associated with numerous important biological functions, but the abnormal phase separation will also dysregulate the physiological processes.
Zhang Songhao +4 more
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Loan loss provisions and return predictability: A dynamic perspective
China Journal of Accounting Research, 2022 This paper examines the impact of loan loss provisions (LLPs) on return predictability during 1994–2017. We find that on average, LLPs are negatively associated with one year ahead stock returns.
Phoebe Gao +3 more
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Journal of Computer and System Sciences, 1982 AbstractA general framework for constructing very small deterministic parsers using a mixed top-down-bottom-up parsing strategy is presented. It is proved that the method leads indeed to valid parsers halting for each input string. Conditions ensuring the determinism of the parser are studied, and bounds on its size are established.
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Journal of Scientific Research in ScienceSupersaturation from amorphous solid dispersions (ASDs) is often limited by liquid–liquid phase separation (LLPS), which can either act as a reservoir for drug-rich droplets or restrict free drug activity, reducing oral absorption.
Anfal J A J Albalol
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Polyphosphate Copper Nanospheres Drive Mitochondrial Metabolic Reprogramming via Calcium Phase Separation for Self‐Sensitizing Cuproptosis [PDF]
Advanced scienceThis study developed polyphosphate (polyP)‐based nanostructures that enable calcium‐mediated metabolic reprogramming via liquid–liquid phase separation (LLPS). Released polyP undergoes LLPS with Ca2+, suppressing glycolytic flux and enhancing mitochondrial metabolism effectively.
Wang J +10 more
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Structure characterization and antioxidant activity analysis of polysaccharides from Lanzhou Lily
Frontiers in Nutrition, 2022 Lanzhou Lily (Lilium davidii var. unicolor) is a traditional medicinal plant and popular edible vegetable bulb in China. In this study, the polysaccharides of Lanzhou Lily (LLPs) were extracted by polyethylene glycol-based ultrasonic-assisted enzymatic ...
Dandan Gao +8 more
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Supramolecular Materials, 2023 Liquid-liquid phase separation (LLPS) is a captivating phenomenon in which a uniform mixture spontaneously divides into two liquid phases with differing component concentrations.
Zhengyu Xu, Wei Wang, Yi Cao, Bin Xue
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