Results 21 to 30 of about 10,769 (286)
Whither Remoteness? Wellesley Partners LLP v Withers LLP [PDF]
The Modern Law Review, 2016 In Wellesley v Withers, the Court of Appeal held that where a defendant is concurrently liable in tort and contract, the contractual rules for the remoteness of loss must apply. Two principal reasons emerge from the judgments. The first, that each party has had the chance to alert the other to unusual risks, is valid but often unconvincing.
openaire +2 more sources
Interaction of multivalent molecules leading to LLPS.
, 2023 At constant environmental conditions (e.g., temperature, ionic strength, pH), the propensity of a multivalent scaffold protein to undergo LLPS only depends on its concentration.
Wolfram Brune (185524) +1 more
core +1 more source
Effects of Mass Change on Liquid–Liquid Phase Separation of the RNA-Binding Protein Fused in Sarcoma
Biomolecules, 2023 In recent years, many experimental and theoretical studies of protein liquid–liquid phase separation (LLPS) have shown its important role in the processes of physiology and pathology.
Weiqian Dong +4 more
doaj +1 more source
Overview of LLPS, phase diagram, and modulation.
, 2021 (A) Under certain conditions, a solvated macromolecule (scaffold) undergo homotypic LLPS and concentrate in a distinct liquid compartment (dense phase). One or more additional macromolecules (clients) can partition into the new phase through heterotypic ...
Mariano Salgueiro (5923637) +7 more
core +1 more source
Differentially expressed LLPS protein-coding genes in pan-cancer.
, 2023 Gene expression level for LLPS protein-coding genes with in vitro, in vivo and in vivo FRAP evidence in 31 types of cancers. The Log2FC of each LLPS protein_coding gene of cancer vs normal.
Zehua Wang (556154) +8 more
core +1 more source
Liquid-liquid phase separation LLPS in biological systems [PDF]
Liquid-liquid phase separation (LLPS) is a process that separates a single homogeneous liquid phase into two distinct phases. This phenomenon is common in biology and is crucial for cell organization and function.
Brzezinski, M.L.
core +8 more sources
International Journal For Multidisciplinary Research, 2023 Allergic rhinitis, an inflammatory immune response to airborne allergens affecting the nasal mucosa, can cause distressing symptoms and disrupt daily life. It often coexists with asthma and lacks an effective conventional treatment. This study explores the successful Ayurvedic treatment of a 51-year-old female patient with perennial allergic rhinitis ...
Ranjana Kaushal -, Deeksha Sharma -
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Abnormal phase separation of biomacromolecules in human diseases
Acta Biochimica et Biophysica Sinica, 2023 Membrane-less organelles (MLOs) formed through liquid-liquid phase separation (LLPS) are associated with numerous important biological functions, but the abnormal phase separation will also dysregulate the physiological processes.
Zhang Songhao +4 more
doaj +1 more source
Loan loss provisions and return predictability: A dynamic perspective
China Journal of Accounting Research, 2022 This paper examines the impact of loan loss provisions (LLPs) on return predictability during 1994–2017. We find that on average, LLPs are negatively associated with one year ahead stock returns.
Phoebe Gao +3 more
doaj +1 more source
Prion‐Like Protein LENG8‐Mediated Nucleation Drives Stress Granule Assembly [PDF]
Advanced scienceLENG8 is a newly identified stress granule (SG) nucleator required for SG assembly. Following stress, nuclear LENG8 granules disassemble, allowing LENG8 to translocate into the cytoplasm and form independent nucleation foci. These foci fuse with canonical early G3BP1/TIA1 seeds via LENG8‐TIA1 binding to drive SG maturation.
Zhang M +6 more
europepmc +2 more sources