Results 91 to 100 of about 281,396 (208)

Long non-coding RNAs in ovarian cancer

Journal of Experimental & Clinical Cancer Research, 2018
Long non-coding RNAs (lncRNAs) refer to functional cellular RNAs molecules longer than 200 nucleotides in length. Unlike microRNAs, which have been widely studied, little is known about the enigmatic role of lncRNAs.
Lei Zhan, Jun Li, Bing Wei
doaj   +1 more source

Non-coding RNA as lung disease biomarkers. [PDF]

, 2015
Biomarkers are quantifiable indicators of disease. These surrogates should be specific, sensitive, predictive, robust and easily accessible. A major class of RNA described as non-coding RNA fulfils many of these criteria, and recent studies have ...
Greene, Catherine M, McKiernan, Paul J, Vencken, Sebastian F   +2 more
core   +1 more source

Integrative analyses of transcriptome sequencing identify novel functional lncRNAs in esophageal squamous cell carcinoma. [PDF]

, 2017
Long non-coding RNAs (lncRNAs) have a critical role in cancer initiation and progression, and thus may mediate oncogenic or tumor suppressing effects, as well as be a new class of cancer therapeutic targets. We performed high-throughput sequencing of RNA
Ai, B, Bai, X-F, Cao, H-H, Feng, C-C, He, J-Z, Huang, G-W, Koeffler, HP, Lei, F, Li, C-Q, Li, E-M, Li, M, Li, S, Li, X, Li, X-C, Liao, L-D, Lin, D-C, Liu, Y-J, Shen, J-H, Tang, Z-D, Wang, L-D, Wang, M-R, Wang, Q-Y, Wang, S-H, Wu, B-L, Wu, J-Y, Wu, Z-Y, Xu, L-Y, Xu, Y-J, Xue, Y-J, Zhang, J, Zhao, J-M, Zheng, C-P, Zhu, Y   +32 more
core   +1 more source

Long Non-Coding RNAs in Vascular Inflammation

Frontiers in Cardiovascular Medicine, 2018
Less than 2% of the genome encodes for proteins. Accumulating studies have revealed a diverse set of RNAs derived from the non-coding genome. Among them, long non-coding RNAs (lncRNAs) have garnered widespread attention over recent years as emerging ...
Stefan Haemmig, Viorel Simion, Mark W. Feinberg   +2 more
doaj   +1 more source

Type I Interferon Regulates the Expression of Long Non-Coding RNAs [PDF]

, 2014
Interferons (IFNs) are key players in the antiviral response. IFN sensing by the cell activates transcription of IFN-stimulated genes (ISGs) able to induce an antiviral state by affecting viral replication and release.
Celia Prior, Dirk Grimm, Elena Carnero, Elizabeth Guruceaga, Kathleen Börner, Marina Barriocanal, Puri Fortes, Victor Segura   +7 more
core   +2 more sources

Long non-coding RNAs in hematopoietic regulation

Cell Regeneration, 2018
Long non-coding RNAs (lncRNAs) have crucial roles via tethering with DNA, RNA or protein in diverse biological processes. These lncRNA-mediated interactions enhance gene regulatory networks and modulate a wide range of downstream genes.
Weiqian Li, Yue Ren, Yanmin Si, Fang Wang, Jia Yu   +4 more
doaj   +1 more source

Long Non-Coding RNAs Dysregulation and Function in Glioblastoma Stem Cells [PDF]

, 2015
published_or_final_versio
KIANG, MY, Leung, GKK, Zhang, P, ZHANG, X   +3 more
core   +1 more source

Targeting long non-coding RNAs (lncRNAs) with oligonucleotides in cancer therapy [PDF]

, 2016
This document is the Accepted Manuscript version of a published work that appeared in final form in Translational Cancer Research.
Pickard, Mark R., Williams, Gwyn T.
core   +1 more source

Molecular and Therapeutic Roles of Non-Coding RNAs in Oral Cancer—A Review

Molecules
Oral cancer (OC) is among the most common malignancies in the world. Despite advances in therapy, the worst-case scenario for OC remains metastasis, with a 50% survival rate.
Vidhya Rekha Umapathy, Prabhu Manickam Natarajan, Bhuminathan Swamikannu   +2 more
doaj   +1 more source

BC200 (BCYRN1) – The shortest, long, non-coding RNA associated with cancer [PDF]

, 2018
With the discovery that the level of RNA synthesis in human cells far exceeds what is required to express protein-coding genes, there has been a concerted scientific effort to identify, catalogue and uncover the biological functions of the non-coding ...
Cronin, S., Dean, Kellie, Samson, Julia
core   +1 more source