Results 11 to 20 of about 185,323 (261)
Long Non-coding RNAs in the Cytoplasm
Genomics, Proteomics & Bioinformatics, 2016 An enormous amount of long non-coding RNAs (lncRNAs) transcribed from eukaryotic genome are important regulators in different aspects of cellular events. Cytoplasm is the residence and the site of action for many lncRNAs.
Farooq Rashid, Abdullah Shah, Ge Shan
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Long Non-coding RNAs In Cancer Progression [PDF]
Frontiers in Genetics, 2012 Recent large-scale transcriptome analyses have revealed that transcription is spread throughout the mammalian genomes, yielding large numbers of transcripts, including long non-coding (lnc) RNAs with little or no protein-coding capacity.
Keiko eTano, Nobuyoshi eAkimitsu
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Long Non-Coding RNAs in Cardiac Remodeling [PDF]
Cellular Physiology and Biochemistry, 2017 Cardiac remodeling occurs after stress to the heart, manifested as pathological processes, including hypertrophy and apoptosis of cardiomyocytes, dysfunction of vascular endothelial cells and vascular smooth muscle cells as well as differentiation and ...
Shutong Shen +4 more
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Long Non-Coding RNAs in Vascular Inflammation [PDF]
Frontiers in Cardiovascular Medicine, 2018 Less than 2% of the genome encodes for proteins. Accumulating studies have revealed a diverse set of RNAs derived from the non-coding genome. Among them, long non-coding RNAs (lncRNAs) have garnered widespread attention over recent years as emerging ...
Stefan Haemmig +2 more
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Long Non-Coding RNA Epigenetics [PDF]
International Journal of Molecular Sciences, 2021 Long noncoding RNAs exceeding a length of 200 nucleotides play an important role in ensuring cell functions and proper organism development by interacting with cellular compounds such as miRNA, mRNA, DNA and proteins. However, there is an additional level of lncRNA regulation, called lncRNA epigenetics, in gene expression control.
Marek Kazimierczyk, Jan Wrzesinski
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Long Non-Coding RNA in Cancer [PDF]
International Journal of Molecular Sciences, 2013 Long non-coding RNAs (lncRNAs) are pervasively transcribed in the genome and are emerging as new players in tumorigenesis due to their various functions in transcriptional, posttranscriptional and epigenetic mechanisms of gene regulation. LncRNAs are deregulated in a number of cancers, demonstrating both oncogenic and tumor suppressive roles, thus ...
Nina Hauptman, Damjan Glavač
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The Involvement of Long Non-Coding RNAs in Bone [PDF]
International Journal of Molecular Sciences, 2021 A harmonious balance between osteoblast and osteoclast activity guarantees optimal bone formation and resorption, pathological conditions affecting the bone may arise. In recent years, emerging evidence has shown that epigenetic mechanisms play an important role during osteoblastogenesis and osteoclastogenesis processes, including long non-coding RNAs (
Aurilia C. +5 more
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Long non-coding RNAs in cancer [PDF]
Science China Life Sciences, 2012 Hunan Key Laboratory of Nonresolving Inflammation and Cancer, Disease Genome Research Center, the Third Xiangya Hospital, Central South University, Changsha 410013, China; Key Laboratory of Carcinogenesis of Ministry of Health, Key Laboratory of Carcinogenesis and Cancer Invasion of Ministry of Education, Cancer Research Institute, Central South ...
Gong, ZhaoJian +15 more
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On the classification of long non-coding RNAs [PDF]
RNA Biology, 2013 Long non-coding RNAs (lncRNAs) have been found to perform various functions in a wide variety of important biological processes. To make easier interpretation of lncRNA functionality and conduct deep mining on these transcribed sequences, it is convenient to classify lncRNAs into different groups.
Ma, Lina +2 more
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Long non-coding RNAs and enhancers [PDF]
Current Opinion in Genetics & Development, 2011 Long non-coding RNAs (ncRNAs) are emerging as important regulatory factors in mammalian genomics. A number of reports within the last 2 years have identified thousands of actively expressed long ncRNA transcripts with distinct properties. The long ncRNAs show differential expression patterns and regulation in a wide variety of cells and tissues, adding
Ulf Andersson, Ørom, Ramin, Shiekhattar
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