Results 21 to 30 of about 185,323 (261)

Long non‐coding RNAs in melanoma [PDF]

Cell Proliferation, 2018
AbstractMelanoma is the most lethal cutaneous cancer with a highly aggressive and metastatic phenotype. While recent genetic and epigenetic studies have shed new insights into the mechanism of melanoma development, the involvement of regulatory non‐coding RNAs remain unclear.
Xin Yu, Heyi Zheng, Gary Tse, Matthew TV Chan, William KK Wu   +4 more
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Epigenetic regulation in myocardial infarction: Non-coding RNAs and exosomal non-coding RNAs

Frontiers in Cardiovascular Medicine, 2022
Myocardial infarction (MI) is one of the leading causes of deaths globally. The early diagnosis of MI lowers the rate of subsequent complications and maximizes the benefits of cardiovascular interventions.
Sara Fadaei, Fatemeh Zarepour, Fatemeh Zarepour, Mehrnoosh Parvaresh, Alireza Motamedzadeh, Seyed Saeed Tamehri Zadeh, Amirhossein Sheida, Amirhossein Sheida, Mohammad Shabani, Mohammad Shabani, Michael R. Hamblin, Mehdi Rezaee, Maryam Zarei, Hamed Mirzaei   +13 more
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Role of Long Non Coding RNAs (lncRNAs) in Colorectal Cancer [PDF]

Zagazig University Medical Journal
Background: Long non-coding RNAs, or lncRNAs are known as a diverse class of RNA transcripts longer than 200 nucleotides that do not encode proteins. Although lncRNAs were once thought to be transcriptional "noise," developments in transcriptomics and ...
Manar Khataby, Heba Pasha, Amal Abdelmeged, Mohamed Abo Ziad, Ahmed Saleh   +4 more
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Autophagy-Related ncRNAs in Pancreatic Cancer

Pharmaceuticals, 2022
Pancreatic cancer (PC) is a malignancy accounting for only 3% of total cancers, but with a low 5-year relative survival rate. Approximately 80% of PC patients are diagnosed at a late stage when the disease has already spread from the primary site ...
Simone Donati, Cinzia Aurilia, Gaia Palmini, Irene Falsetti, Teresa Iantomasi, Maria Luisa Brandi   +5 more
doaj   +1 more source

Long non‐coding RNA modifies chromatin [PDF]

BioEssays, 2011
AbstractCommon themes are emerging in the molecular mechanisms of long non‐coding RNA‐mediated gene repression. Long non‐coding RNAs (lncRNAs) participate in targeted gene silencing through chromatin remodelling, nuclear reorganisation, formation of a silencing domain and precise control over the entry of genes into silent compartments.
Alka Saxena, Piero Carninci??
openaire   +2 more sources

MicroRNA-encoding long non-coding RNAs

BMC Genomics, 2008
Background Recent analysis of the mouse transcriptional data has revealed the existence of ~34,000 messenger-like non-coding RNAs (ml-ncRNAs). Whereas the functional properties of these ml-ncRNAs are beginning to be unravelled, no functional information ...
Zhu Xiaopeng, He Dandan, He Housheng, Skogerbø Geir, Liu Changning, Su Hua, He Shunmin, Liu Tao, Zhao Yi, Chen Runsheng   +9 more
doaj   +1 more source

Roles of Non-coding RNAs and Angiogenesis in Glioblastoma

Frontiers in Cell and Developmental Biology, 2021
One of the significant hallmarks of cancer is angiogenesis. It has a crucial function in tumor development and metastasis. Thus, angiogenesis has become one of the most exciting targets for drug development in cancer treatment.
Ebrahim Balandeh, Kimia Mohammadshafie, Yaser Mahmoudi, Mohammad Hossein Pourhanifeh, Ali Rajabi, Ali Rajabi, Zahra Razaghi Bahabadi, Zahra Razaghi Bahabadi, Amir Hossein Mohammadi, Neda Rahimian, Michael R. Hamblin, Hamed Mirzaei   +11 more
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Long Non-Coding RNAs in Endometrial Carcinoma [PDF]

International Journal of Molecular Sciences, 2015
Endometrial carcinoma (EC), the second most common form of gynaecological malignancy, can be divided into two distinct sub-types: Type I tumours arise from hyperplastic endometrium and typically effect women around the time of menopause, whereas type II tumours arise in postmenopausal women from atrophic endometrium.
Maria Smolle, Marc Bullock, Hui Ling, Martin Pichler, Johannes Haybaeck   +4 more
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Genome-wide analysis of long non-coding RNA expression and function in colorectal cancer

Tumor Biology, 2017
Long non-coding RNAs (lncRNAs) are widely transcribed in the genome, but their expression profile and roles in colorectal cancer are not well understood.
Fangyuan Jing, Huicheng Jin, Yingying Mao, Yingjun Li, Ye Ding, Chunhong Fan, Kun Chen   +6 more
doaj   +1 more source

Deciphering the Functional Long Non‐Coding RNAs Derived from MicroRNA Loci

Advanced Science, 2023
Albeit the majority of eukaryotic genomes can be pervasively transcribed to a diverse population of lncRNAs and various subtypes of lncRNA are discovered. However, the genome‐wide study of miRNA‐derived lncRNAs is still lacking. Here, it is reported that
Weiqian Li, Yue Huo, Yue Ren, Chenxi Han, Shuo Li, Kangning Wang, Manman He, Yiying Chen, Yanran Wang, Lingjie Xu, Yuehong Guo, Yanmin Si, Yufeng Gao, Jiayue Xu, Xiaoshuang Wang, Yanni Ma, Jia Yu, Fang Wang   +17 more
doaj   +1 more source