Genome-wide analysis of long non-coding RNA expression and function in colorectal cancer
Tumor Biology, 2017 Long non-coding RNAs (lncRNAs) are widely transcribed in the genome, but their expression profile and roles in colorectal cancer are not well understood.
Fangyuan Jing +6 more
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Deciphering the Functional Long Non‐Coding RNAs Derived from MicroRNA Loci
Advanced Science, 2023 Albeit the majority of eukaryotic genomes can be pervasively transcribed to a diverse population of lncRNAs and various subtypes of lncRNA are discovered. However, the genome‐wide study of miRNA‐derived lncRNAs is still lacking. Here, it is reported that
Weiqian Li +17 more
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Angiogenesis-related non-coding RNAs and gastrointestinal cancer
Molecular Therapy: Oncolytics, 2021 Gastrointestinal (GI) cancers are among the main reasons for cancer death globally. The deadliest types of GI cancer include colon, stomach, and liver cancers.
Zahra Sadat Razavi +7 more
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Long non-coding RNAs in C. elegans [PDF]
, 2012 Thousands of long non-coding RNAs (lncRNAs) have been found in vertebrate animals, a few of which have known biological roles. To better understand the genomics and features of lncRNAs in invertebrates, we used available RNA-seq, poly(A)-site, and ...
Bartel, David, Nam, Jin-Wu
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Studies on the role of non-coding RNAs in controlling the activity of T cells in asthma
Non-coding RNA Research, 2023 Bronchial asthma, commonly known as asthma, is a chronic inflammatory disease characterized by airway inflammation, increased responsiveness and changes in airway structure. T cells, particularly T helper cells, play a crucial role in the disease.
Albert Sufianov +8 more
doaj +1 more source
PLIT: An alignment-free computational tool for identification of long non-coding RNAs in plant transcriptomic datasets [PDF]
, 2019 Long non-coding RNAs (lncRNAs) are a class of non-coding RNAs which play a significant role in several biological processes. RNA-seq based transcriptome sequencing has been extensively used for identification of lncRNAs.
Deshpande, Sumukh +4 more
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Lithium alters expression of RNAs in a type-specific manner in differentiated human neuroblastoma neuronal cultures, including specific genes involved in Alzheimer's disease. [PDF]
, 2019 Lithium (Li) is a medication long-used to treat bipolar disorder. It is currently under investigation for multiple nervous system disorders, including Alzheimer's disease (AD).
Balaraman, Yokesh +7 more
core +3 more sources
Long Non-Coding RNAs in Cardiac Hypertrophy [PDF]
Frontiers in Molecular Medicine, 2022 Heart disease represents one of the main challenges in modern medicine with insufficient treatment options. Whole genome sequencing allowed for the discovery of several classes of non-coding RNA (ncRNA) and widened our understanding of disease regulatory circuits.
Mangraviti, Nicolò, De Windt, Leon J
openaire +2 more sources
Long Non-Coding RNAs in Endometrial Carcinoma [PDF]
International Journal of Molecular Sciences, 2015 Endometrial carcinoma (EC), the second most common form of gynaecological malignancy, can be divided into two distinct sub-types: Type I tumours arise from hyperplastic endometrium and typically effect women around the time of menopause, whereas type II tumours arise in postmenopausal women from atrophic endometrium.
Maria Smolle +4 more
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Non-Coding RNAs Including miRNAs and lncRNAs in Cardiovascular Biology and Disease [PDF]
, 2014 It has been recognized for decades that proteins, which are encoded by our genome and produced via transcription and translation steps, are building blocks that play vital roles in almost all biological processes.
Kataoka, Masaharu, Wang, Da-Zhi
core +2 more sources