Results 41 to 50 of about 281,396 (208)
Cell cycle regulation by long non-coding RNAs [PDF]
, 2013 The mammalian cell cycle is precisely controlled by cyclin-dependent kinases (CDKs) and related pathways such as the RB and p53 pathways. Recent research on long non-coding RNAs (lncRNAs) indicates that many lncRNAs are involved in the regulation of ...
Hiroyuki Niida +4 more
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Cardiomyopathies: The Role of Non-Coding RNAs
Non-Coding RNACardiomyopathies are the structural and functional disorders of the myocardium. Etiopathogenesis is complex and involves an interplay of genetic, environmental, and lifestyle factors eventually leading to myocardial abnormalities.
Nicole Carabetta +7 more
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Non-coding RNAs in Transcriptional Regulation [PDF]
, 2015 Transcriptional gene silencing guided by small RNAs is a process conserved from protozoa to mammals. Small RNAs loaded into Argonaute family proteins direct repressive histone modifications or DNA cytosine methylation to homologous regions of the genome.
Aravin, Alexei A., Chen, Yung-Chia Ariel
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Molecular Therapy: Nucleic Acids, 2017 The popularization of genome-wide analyses and RNA sequencing led to the discovery that a large part of the human genome, while effectively transcribed, does not encode proteins. Long non-coding RNAs have emerged as critical regulators of gene expression
Clarissa P.C. Gomes +7 more
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Long Non-Coding RNAs as “MYC Facilitators”
Pathophysiology, 2023 In this article, we discuss a class of MYC-interacting lncRNAs (long non-coding RNAs) that share the following criteria: They are direct transcriptional targets of MYC. Their expression is coordinated with the expression of MYC.
Daniel García-Caballero +2 more
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Long non-coding RNAs as novel components in the TP53 pathway [PDF]
, 2016 C
Koster, Jan +8 more
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Variable performance of lncRNA in breast cancer
Journal of Current Oncology and Medical Sciences, 2021 Breast cancer, is one of most frequent cancers across women, is recognized as a diverse and difficult disease that continues to be a serious public health problem.
Sogand Vahidi +3 more
doaj
Long non-coding RNA expression profiling in the NCI60 cancer cell line panel using high-throughput RT-qPCR [PDF]
, 2016 Long non-coding RNAs (lncRNAs) form a new class of RNA molecules implicated in various aspects of protein coding gene expression regulation. To study lncRNAs in cancer, we generated expression profiles for 1707 human lncRNAs in the NCI60 cancer cell line
Derveaux, Stefaan +5 more
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Noncoder : a web interface for exon array-based detection of long non-coding RNAs [PDF]
, 2012 Due to recent technical developments, a high number of long non-coding RNAs (lncRNAs) have been discovered in mammals. Although it has been shown that lncRNAs are regulated differently among tissues and disease statuses, functions of these transcripts ...
Braun, Thomas +3 more
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Cancer Cell InternationalAutophagy is a cellular process that involves the degradation and recycling of cellular components, including damaged proteins and organelles. It is an important mechanism for maintaining cellular homeostasis and has been implicated in various diseases ...
Yan Dong +6 more
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