Results 61 to 70 of about 281,396 (208)

Circular RNAs as novel regulators of β-cell functions in normal and disease conditions. [PDF]

, 2018
There is strong evidence for an involvement of different classes of non-coding RNAs, including microRNAs and long non-coding RNAs, in the regulation of β-cell activities and in diabetes development.
Guay, C., Kjems, J., Laybutt, D.R., Lee, K., Regazzi, R., Rodriguez-Trejo, A., Sobel, J., Stoll, L., Venø, M.T.   +8 more
core   +2 more sources

Uncovering RNA Editing Sites in Long Non-Coding RNAs [PDF]

Frontiers in Bioengineering and Biotechnology, 2014
RNA editing is an important co/post-transcriptional molecular process able to modify RNAs by nucleotide insertions/deletions or substitutions. In human, the most common RNA editing event involves the deamination of adenosine (A) into inosine (I) through the adenosine deaminase acting on RNA proteins. Although A-to-I editing can occur in both coding and
Ernesto ePicardi, Ernesto ePicardi, Anna Maria D'Erchia, Anna Maria D'Erchia, Angela eGallo, Antonio eMontalvo, Antonio eMontalvo, Graziano ePesole, Graziano ePesole   +8 more
openaire   +5 more sources

Long Non-Coding RNAs in Haematological Malignancies [PDF]

International Journal of Molecular Sciences, 2013
Long non-coding RNAs (lncRNAs) are functional RNAs longer than 200 nucleotides in length. LncRNAs are as diverse as mRNAs and they normally share the same biosynthetic machinery based on RNA polymerase II, splicing and polyadenylation. However, lncRNAs have low coding potential.
Andoni Garitano-Trojaola, Xabier Agirre, Felipe Prósper, Puri Fortes   +3 more
openaire   +2 more sources

Peptidomic discovery of short open reading frame-encoded peptides in human cells [PDF]

, 2014
The amount of the transcriptome that is translated into polypeptides is of fundamental importance. We developed a peptidomic strategy to detect short ORF (sORF)-encoded polypeptides (SEPs) in human cells. We identified 90 SEPs, 86 of which are novel, the
Budnik, Bogdan A., Cabili, Moran N., Karger, Amir, Levin, Joshua Z., Ma, Jiao, Mitchell, Andrew J., Rinn, John L., Saghatelian, Alan, Schwaid, Adam G., Slavoff, Sarah A.   +9 more
core   +1 more source

Long non-coding RNAs: The key players in glioma pathogenesis [PDF]

, 2015
published_or_final_versio
Kiang, KMY, Leung, GKK, Zhang, XQ
core   +2 more sources

Potential prognostic long non-coding RNA identification and their validation in predicting survival of patients with multiple myeloma

Tumor Biology, 2017
Multiple myeloma, a typical hematological malignancy, is characterized by malignant proliferation of plasma cells. This study was to identify differently expressed long non-coding RNAs to predict the survival of patients with multiple myeloma efficiently.
Ai-Xin Hu, Zhi-Yong Huang, Lin Zhang, Jian Shen   +3 more
doaj   +1 more source

Integrated Analysis of Long Non-Coding RNA and mRNA Expression Profiles in Testes of Calves and Sexually Mature Wandong Bulls (Bos taurus)

Animals, 2021
The mRNAs and long non-coding RNAs axes are playing a vital role in the regulating of post-transcriptional gene expression. Thereby, elucidating the expression pattern of mRNAs and long non-coding RNAs underlying testis development is crucial.
Hongyu Liu, Ibrar Muhammad Khan, Huiqun Yin, Xinqi Zhou, Muhammad Rizwan, Jingyi Zhuang, Yunhai Zhang   +6 more
doaj   +1 more source

miRcode: A map of putative microRNA target sites in the long non-coding transcriptome [PDF]

, 2012
Summary: Although small non-coding RNAs, such as microRNAs, have well-established functions in the cell, long non-coding RNAs (lncRNAs) have only recently started to emerge as abundant regulators of cell physiology, and their functions may be diverse.
Jeggari, Ashwini, Larsson, Erik, Marks, Debora   +2 more
core   +1 more source

Viruses hijack a long non-coding RNA [PDF]

Nature, 2017
Manipulation of host-cell metabolism is an essential aspect of viral replication cycles. Viral co-option of a cellular long non-protein-coding RNA has now been found to be a key step in this process. Manipulation of host-cell metabolism is an essential aspect of viral replication cycles. Viral co-option of a cellular long non-protein-coding RNA has now
Nicholas S, Heaton, Bryan R, Cullen
openaire   +2 more sources

Direct and indirect role of non-coding RNAs in company with amyloid and tau protein in promoting neuroinflammation in post-ischemic brain neurodegeneration

Frontiers in Cellular Neuroscience
Post-ischemic brain neurodegeneration with subsequent neuroinflammation is a major cause of mortality, permanent disability, and the development of Alzheimer’s disease type dementia in the absence of appropriate treatment.
Ryszard Pluta
doaj   +1 more source