Results 121 to 130 of about 713,910 (249)

Integrative characterization of G-Quadruplexes in the three-dimensional chromatin structure

Epigenetics, 2019
DNA molecules are highly compacted in the eukaryotic nucleus where distal regulatory elements reach their targets through three-dimensional chromosomal interactions.
Yue Hou, Fuyu Li, Rongxin Zhang, Sheng Li, Hongde Liu, Zhaohui S. Qin, Xiao Sun   +6 more
doaj   +1 more source

A Constraint‐Based Analytical Framework for Design‐Space Analysis and Material Screening of Tubular Multilayer Dielectric Elastomer Pumps for Extracorporeal Circulatory Applications

Advanced Materials Technologies, EarlyView.
A constraint‐based analytical framework maps the coupled effects of material properties, structural parameters, and operating conditions in tubular dielectric elastomer pumps for extracorporeal circulatory applications. The approach defines performance boundaries through mechanical, electrical, and hydraulic constraints and identifies feasible design ...
Yan Zhang, Amine Benouhiba, Yoan Civet, Yves Perriard   +3 more
wiley   +1 more source

Silk Fibroin Nanofiber–Immobilized Horseradish Peroxidase Enables Continuous Preparation of Injectable Hydrogels With Negligible Residual Enzyme for Drug Delivery

Advanced Materials Technologies, EarlyView.
Overcoming the immunogenicity challenges of enzyme‐mediated crosslinking, a flow‐through reactor utilizing SFNF‐HRP enables the continuous production of injectable hydrogels. This continuous platform ensures homogeneous crosslinking while minimizing residual HRP in the resulting hydrogels.
Ayari Miyawaki, Shinji Sakai
wiley   +1 more source

Programming Actuation in 3D‐Printed Micro‐Architectures via Interfacial Adhesion Control

Advanced Materials Technologies, EarlyView.
A two‐phase meniscus‐guided 3D printing method directly fabricates microscale poly(3,4‐ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS) and poly(vinyl alcohol) (PVA) bilayers with in situ programmable interfaces. Modulating the meniscus stretching speed switches the interface between separated and bonded states, which controls the mechanical ...
Xiao Huan, Juhyung Kim, Yujin Park, Shiqi Hu, Jihyuk Yang, Nan Huang, Feipeng Chen, Yu Liu, Sixi Cao, Zhuoran Wang, Ho Cheung Shum, Barbara Pui Chan, Dongwoon Shin, Ji Tae Kim   +13 more
wiley   +1 more source

Zero‐Waste Manufacturing of Ophthalmic Lenses by Direct Fluidic Shaping in Arbitrary Domains

Advanced Materials Technologies, EarlyView.
Conventional ophthalmic lens manufacturing discards up to 97% of material through subtractive processes. The Cookie Cutter algorithm extends Fluidic Shaping to arbitrary rim geometries. The framework prescribes a spatially varying boundary height that, under neutral buoyancy and surface tension, shapes curable polymer into spherocylindrical lenses that
Yotam Katzman, Mor Elgarisi, Amos A. Hari, Jonathan Ericson, Omer Luria, Valeri Frumkin, Moran Bercovici   +6 more
wiley   +1 more source

Closed Loop Reference Optimization for Extrusion Additive Manufacturing

CoRR
Various defects occur during material extrusion additive manufacturing processes that degrade the quality of the 3D printed parts and lead to significant material waste. This motivates feedback control of the extrusion process to mitigate defects and prevent print failure. We propose a linear quadratic regulator (LQR) for closed-loop control with force
Rawan Hoteit, Andrea Balestra, Nathan Mingard, Efe C. Balta, John Lygeros   +4 more
openaire   +2 more sources

Spatial Stiffness Programming in Single‐Filament Material Extrusion Through Data‐Driven Thermal Foaming

Advanced Materials Technologies, EarlyView.
Single‐filament material extrusion enables spatial stiffness programming through locally controlled thermal foaming of TPU. A data‐driven G‐code framework tunes porosity from 15.7% to 40.7% and hardness from 90 to 63 Shore A within and across layers. Monolithic hands and soft actuators consequently achieve distinct programmed motions without material ...
Rosanna Rifino, Gianni Stano, Mahdi Bodaghi, Gianluca Percoco   +3 more
wiley   +1 more source

Exuberant long noncoding RNA expression may sculpt Igh locus topology

Frontiers in Immunology
Diverse Igh repertoires require successful V(D)J recombination allowing B cell receptor expression and Ig secretion for humoral immune responses. Igh locus contraction has been implicated in generating spatial proximity between distal VH segments and the
Ellen B. Drake, Sarah Naiyer, Xinyan Qu, Khalid Bhat, Hammad Farooq, Mark Maienschein-Cline, Jie Liang, Amy L. Kenter   +7 more
doaj   +1 more source

3D‐Printed Actuator Powered by Liquid Crystal Elastomer Muscles at the Water–Air Interface

Advanced Materials Technologies, EarlyView.
Soft robots for unstructured environments require responsive, durable actuators. Liquid crystal elastomers (LCEs) provide large reversible deformations under thermal or optical stimuli. Direct ink writing enables fabrication of LCE actuators integrated with silicone, with mesogen chemistry and oligomers optimized for printable inks.
Cecilie Ryberg, Stefan Pendlmayr, Jan Skov Pedersen, Jens Vinge Nygaard, Jan P. F. Lagerwall, Brigitte Städler   +5 more
wiley   +1 more source

Extrusion‐Based Bioprinting of Living Bioinks for Tissue and Organ Engineering

Advanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting is presented as the most versatile route for fabricating living, heterogeneous tissues. Its ability to combine diverse bioinks, support matrices, and advanced printhead geometries transforms familiar constraints into powerful biofabrication opportunities.
Eric Silberman, Ester Sapir Baruch, Roni Cohen, Assaf Shapira, Tal Dvir   +4 more
wiley   +1 more source