Results 121 to 130 of about 19,057 (244)

Investigating Phase Separation in Genome Folding via Multiscale Computational Modeling

Advanced Science
The 3D organization of the genome is central to gene regulation, and phase separation has emerged as an important physical principle for this architecture.
Jiahu Tang, Cibo Feng, Haibin Su, Xiakun Chu   +3 more
doaj   +1 more source

A High‐Resolution THz‐PCF Sensing Framework: Precise Identification of Food Preservatives Through Refractive Index Analysis

Advanced Materials Interfaces, EarlyView.
As presented in the graphical abstract, it depicts an image of a terahertz photonic crystal fiber (THz‐PCF) sensor with a polygonal shape in the core, which is filled with an analyte, and air slots in the cladding. The THz waves will travel through the fiber, and due to increased light‐matter interaction in the sensing region, changes in refractive ...
T. H. M. Sumon Rashid, Md. Nayem Hossain, Md. Golam Kibria, A. H. M. Iftekharul Ferdous, Jabin Tasnin Upoma, Md. Lalon Hossain, Sajad Ali   +6 more
wiley   +1 more source

Negotiating in a Foreign Land: Understanding the Curious Interactions Between Intracellular Mitochondria and Internalized Nanoparticles

Advanced Materials Interfaces, EarlyView.
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley   +1 more source

Condensin complexes: from chromatin organization to disease

Nucleus
Condensin complexes are indispensable for mitotic chromosome condensation. In this review, we summarize their structural and functional features, focusing on ATP-dependent loop extrusion and mitotic chromatin folding. We discuss current models of mitotic
Lirong Shu, Haoyue Zhang
doaj   +1 more source

Integrative characterization of G-Quadruplexes in the three-dimensional chromatin structure

Epigenetics, 2019
DNA molecules are highly compacted in the eukaryotic nucleus where distal regulatory elements reach their targets through three-dimensional chromosomal interactions.
Yue Hou, Fuyu Li, Rongxin Zhang, Sheng Li, Hongde Liu, Zhaohui S. Qin, Xiao Sun   +6 more
doaj   +1 more source

Additive‐Manufactured, Multifunctional Bioreactor Technology for Dynamic Culture of 3D Bioprinted Tissue Models

Advanced Materials Technologies, EarlyView.
We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger, Johann Schorzmann, Hsuan‐Heng Lu, Muhammad Osama, Julian Bauer, Michael Haug, Oliver Friedrich, Aldo R. Boccaccini, Frank Döpper, Sahar Salehi   +9 more
wiley   +1 more source

Exuberant long noncoding RNA expression may sculpt Igh locus topology

Frontiers in Immunology
Diverse Igh repertoires require successful V(D)J recombination allowing B cell receptor expression and Ig secretion for humoral immune responses. Igh locus contraction has been implicated in generating spatial proximity between distal VH segments and the
Ellen B. Drake, Sarah Naiyer, Xinyan Qu, Khalid Bhat, Hammad Farooq, Mark Maienschein-Cline, Jie Liang, Amy L. Kenter   +7 more
doaj   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

Advanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le, Anh Tuan Trong Tran, Ammara Waheed, Tran Thanh Tung, Dusan Losic   +4 more
wiley   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Soft Robotic Snake with Tunable Undulatory Gait for Efficient Underwater Locomotion

Advanced Robotics Research, EarlyView.
This study designs an underwater soft snake robot using 3D‐printed soft actuators, controlled by specific signals to generate sinusoidal undulation. Results show a positive correlation between speed and swing amplitude, with optimal performance at 2/3π phase offset, PLA tail, 1.2 voltage growth rate, and 6s undulation period achieving a maximum speed ...
Huichen Ma, Junjie Zhou, Raye Yeow
wiley   +1 more source