Results 101 to 110 of about 19,057 (244)

Numerical modelling of the aluminium extrusion process [PDF]

The extrusion of aluminium alloys involves the shaping of the product from an homogenised billet into a complex shape. In addition the properties of the extrudate are closely related to the processing parameters (temperature, stain rate, and material ...
Peng, Z.
core  

Rapid Fabrication of Self‐Propelled and Steerable Magnetic Microcatheters for Precision Medicine

Advanced Materials, EarlyView.
A rapid Joule heating fabrication method for the production of self‐propelling, adaptive microcatheters, with tunable stiffness and integrated microfluidic channels is presented. Demonstrated through three microrobotic designs, including a steerable guiding catheter, an untethered wave‐crawling TubeBot, and a distal‐end propelled microcatheter, it was ...
Zhi Chen, Boris Rivkin, David Castellanos‐Robles, Ivan Soldatov, Lukas Beyer, Mariana Medina‐Sánchez   +5 more
wiley   +1 more source

USP7 promotes IgA class switching through stabilizing RUNX3 for germline transcription activation

Cell Reports
Summary: Class switch recombination (CSR) diversifies the effector functions of antibodies and involves complex regulation of transcription and DNA damage repair.
Bo Zhao, Zhigang Xia, Beibei Yang, Yao Guo, Ruizhi Zhou, Mingyu Gu, Meiling Liu, Qingcheng Li, Wanyu Bai, Junbin Huang, Xuefei Zhang, Chengming Zhu, Kam Tong Leung, Chun Chen, Junchao Dong   +14 more
doaj   +1 more source

A DNA tension-dependent tug-of-war between dimeric SMC motors governs loop extrusion directionality [PDF]

Structural maintenance of chromosome (SMC) complexes organize and regulate genomes via DNA loop extrusion. During this process, the complexes increase the loop size by reeling in DNA from one or both sides of the loop. The factors governing this symmetry
Pradhan B, Pinto A, Tetiker D, Kanno T, Fisher GLM, Baaske MD, Cutts EE, Chatzicharlampous C, Schüler H, Deep A, Corbett KD, Aragon L, Virnau P, Björkegren C, Kim E.   +14 more
europepmc   +2 more sources

Ammonium Salts as Curing Agents to Obtain Ionic Epoxy Resins With a Thermoplastic‐to‐Thermoset Transition

Advanced Materials, EarlyView.
Ionic epoxy networks are prepared using ammonium salts as hardeners, leading to a two‐stage curing process with a thermoplastic‐like intermediate. This uncommon behavior enables extrusion and fabrication of thermoplastic prepregs that can be cured into thermoset composites.
Izabela Kurowska, Leire Unanue, Itxaso Calafel, Dorleta Otaegui, Jorge L. Olmedo‐Martínez, Lourdes Irusta, Daniel Vinagre, Nora Aranburu, Nerea Casado, Ibon Odriozola, David Mecerreyes   +10 more
wiley   +1 more source

Cohesin Disrupts Polycomb-Dependent Chromosome Interactions in Embryonic Stem Cells

Cell Reports, 2020
Summary: How chromosome organization is related to genome function remains poorly understood. Cohesin, loop extrusion, and CCCTC-binding factor (CTCF) have been proposed to create topologically associating domains (TADs) to regulate gene expression. Here,
James D.P. Rhodes, Angelika Feldmann, Benjamín Hernández-Rodríguez, Noelia Díaz, Jill M. Brown, Nadezda A. Fursova, Neil P. Blackledge, Praveen Prathapan, Paula Dobrinic, Miles K. Huseyin, Aleksander Szczurek, Kai Kruse, Kim A. Nasmyth, Veronica J. Buckle, Juan M. Vaquerizas, Robert J. Klose   +15 more
doaj   +1 more source

Self‐Assembled Monolayers in p–i–n Perovskite Solar Cells: Molecular Design, Interfacial Engineering, and Machine Learning–Accelerated Material Discovery

Advanced Materials, EarlyView.
This review highlights the role of self‐assembled monolayers (SAMs) in perovskite solar cells, covering molecular engineering, multifunctional interface regulation, machine learning (ML) accelerated discovery, advanced device architectures, and pathways toward scalable fabrication and commercialization for high‐efficiency and stable single‐junction and
Asmat Ullah, Ying Luo, Stefaan De Wolf
wiley   +1 more source

Stable Protein‐Based G‐Quadruplex‐Derived Supramolecular Bioinks as Tunable ECM‐Mimetic Constructs Assembled by Combining Non‐Covalent and Covalent Strategies

Advanced Materials, EarlyView.
Harnessing the synergistic interplay of supramolecular self‐assembly, under macromolecular crowding conditions, and enzymatic‐mediated covalent crosslinking toward a stable protein‐based G‐quadruplex‐derived supramolecular bioink. This bioinspired strategy enables the biofabrication of complex and tunable ECM‐mimetic constructs, providing a platform ...
Vera Sousa, Rita Sobreiro‐Almeida, Bart W. L. van den Bersselaar, E. W. Meijer, Ghislaine Vantomme, João Borges, João F. Mano   +6 more
wiley   +1 more source

Open-Loop Control System for High Precision Extrusion-Based Bioprinting Through Machine Learning Modeling [PDF]

Bioprinting is a process that uses 3D printing techniques to combine cells, growth factors, and biomaterials to create biomedical components, often with the aim of imitating natural tissue characteristics.
Javier Arduengo, CHINESTA SORIA, Francisco, Chinesta, Francisco, HASCOËT, Nicolas, ARDUENGO, Javier, Jean-Yves Hascoet, Francisco Chinesta, HASCOET, Jean-Yves, Nicolas Hascoet   +8 more
core   +1 more source

Loop extrusion by cohesin plays a role in enhancer-activated gene expression early in differentiation

Nature Communications
Enhancers and their target promoters often come into close physical proximity when activated. This may be explained by a variety of mechanisms, including cohesin-mediated chromatin loop extrusion.
Rosa J. Stolper, Felice H. Tsang, Emily Georgiades, Lars L. P. Hanssen, Edward A. J. Tunnacliffe, Damien J. Downes, Caroline L. Harrold, Jim R. Hughes, Robert A. Beagrie, Benjamin Davies, Mira T. Kassouf, Douglas R. Higgs   +11 more
doaj   +1 more source