Results 81 to 90 of about 713,910 (249)

Anisotropic scrunching of SMC with a baton-pass mechanism

Communications Biology
DNA-loop extrusion is considered to be a universal principle of structural maintenance of chromosome (SMC) proteins with regard to chromosome organization.
Kyoung-Wook Moon, Do-Gyun Kim, Je-Kyung Ryu   +2 more
doaj   +1 more source

2D Skeletal Muscle Thin Film Actuators Enhance Efficiency of Biohybrid Robots

Advanced Functional Materials, EarlyView.
2D skeletal muscle thin film actuators generate millinewton‐scale forces and millimeter‐scale strokes while remaining functional for over 30 days. Their force density is 20‐fold higher than 3D skeletal muscle actuators, enabling multi‐fin robots with tunable speed and multidirectional steering.
Maheera Bawa, Arielle Berman, Laura Schwendeman, Ferdows Afghah, Seanbiron Johnson, Ritu Raman   +5 more
wiley   +1 more source

Closed-Loop Control of Extrusion-Based Bioprinting Through Real-Time Computer Vision

Bioprinting is the technology that combines the use of living matter and biomaterials to manufacture biological models, tissues, and structures layer by layer for applications in regenerative medicine, drug testing, and tissue engineering.
Javier Arduengo, Nicolas Hascoët, Jean-Yves Hascoet, Francisco Chinesta   +3 more
core   +1 more source

ATP‐Mediated Bidirectional Communication Between Natural and Artificial Cells for Controlled Bioreactions

Advanced Functional Materials, EarlyView.
Establishment of bidirectional communication behavior between natural and artificial cells. The first type of communication from natural dendritic cells to artificial polymeric cells was achieved via ATP release after cell lysis. The released ATP was taken up via gated UV‐controlled permeability increase of the polymeric membrane for performing ...
Ilona Kalte, Tsvetomir Ivanov, Leonhard Seufert, Shoupeng Cao, Lucas Caire da Silva, Volker Mailänder, Katharina Landfester   +6 more
wiley   +1 more source

High-resolution CTCF footprinting reveals impact of chromatin state on cohesin extrusion

Nature Communications
Cohesin-mediated DNA loop extrusion enables gene regulation by distal enhancers through the establishment of chromosome structure and long-range enhancer-promoter interactions.
Corriene E. Sept, Y. Esther Tak, Viraat Goel, Mital S. Bhakta, Christian G. Cerda-Smith, Haley M. Hutchinson, Marco Blanchette, Christine E. Eyler, Sarah E. Johnstone, J. Keith Joung, Anders S. Hansen, Martin J. Aryee   +11 more
doaj   +1 more source

Scc2 counteracts a Wapl-independent mechanism that releases cohesin from chromosomes during G1

eLife, 2019
Cohesin’s association with chromosomes is determined by loading dependent on the Scc2/4 complex and release due to Wapl. We show here that Scc2 also actively maintains cohesin on chromosomes during G1 in S. cerevisiae cells. It does so by blocking a Wapl-
Madhusudhan Srinivasan, Naomi J Petela, Johanna C Scheinost, James Collier, Menelaos Voulgaris, Maurici B Roig, Frederic Beckouët, Bin Hu, Kim A Nasmyth   +8 more
doaj   +1 more source

Mechanics of Telson Ridges in Mantis Shrimp for Impact Analysis and Implications for Bioinspired Elastic Shell Designs

Advanced Functional Materials, EarlyView.
The mantis shrimp telson reveals how ridged biological shields control deformation under impact. Inspired by this architecture, telson‐inspired ridged curved shells transform ridge geometry and macroscopic curvature into bidirectional snap‐through, tunable stiffness, and enhanced hysteretic energy dissipation for multifunctional architected materials ...
Phani Saketh Dasika, Adwait Trikanad, Wei Huang, Taige Hao, David Kisailus, Pablo D. Zavattieri   +5 more
wiley   +1 more source

Adam Wyeth: a patron of LOOP

Loop is delighted and honoured to announce that poet and playwright Adam Wyeth, who lives and works in Dublin, is as of June 2024 a patron of Loop. We look forward to continuing our conversation with Adam, begun at the excellent 2024 SAES Congress at ...
The LOOP team
core   +1 more source

Additively Manufactured Geometry‐Reconfigurable Soft Neural Probes With Monolithic Multifunctionality

Advanced Functional Materials, EarlyView.
A geometry‐reconfigured additive manufacturing strategy converts planar printed soft materials into soft compact neural probes with integrated hydrogel electrodes and microfluidic channels. The resulting NeuroMAP platform enables scalable multichannel recording, localized chemical delivery, stable in vivo electrophysiological recording, and reduced ...
Hyunjin Lee, Xinyi Wang, Sirui Li, Jihyang Park, Hyunseok Lee, Jianting Yao, Kedar Narayan, Yuqi Wang, Jiashu Ren, Yueqi Deng, Salahuddin Ahmed, Denver I. Greenawalt, Archana Pandiyan, Loganathan Veeramuthu, Chi‐Ching Kuo, Tao Zhou   +15 more
wiley   +1 more source

Fundamental roles of chromatin loop extrusion in antibody class switching [PDF]

Nature, 2019
Antibody class switch recombination (CSR) in B lymphocytes replaces immunoglobulin heavy chain locus (Igh) Cμ constant region exons (CHs) with one of six CHs lying 100-200 kb downstream1. Each CH is flanked upstream by an I promoter and long repetitive switch (S) region1.
Zhang, Xuefei, Zhang, Yu, Ba, Zhaoqing, Kyritsis, Nia, Alt, Frederick, Casellas, Rafael   +5 more
openaire   +4 more sources