Results 11 to 20 of about 6,251 (206)

RESVERATROL AND LORATADINE EFFECTS ON OXIDATIVE STRESS INDUCED BY EXPERIMENTAL INFLAMMATION [PDF]

open access: yesStudia Universitatis Babes-Bolyai Chemia, 2017
Resveratrol is a polyphenol with important antioxidant and anti-inflammatory roles. Loratadine, as a selective inverse-agonist of peripheral receptor H1, is described as an anti-allergic substance with potential anti-inflammatory effects.
Daniela-Rodica MITREA   +7 more
doaj   +2 more sources

Development, stability and in vitro delivery profile of new loratadine-loaded nanoparticles

open access: yesSaudi Pharmaceutical Journal, 2017
Purpose: Loratadine is used as antihistaminic without side effects in nervous systems. This drug is a weak base and it is absorbed from the intestine. The nitrogen of the pyridine ring is protonated in the stomach affecting the oral bioavailability.
Jesus Rafael Rodriguez Amado   +7 more
doaj   +2 more sources

Simultaneous determination of loratadine and preservatives in syrups by thin-layer chromatography

open access: yes, 2007
Simple, rapid, and precise densitometric TLC methods have been established for simultaneous determination of loratadine and preservatives in loratadine-sodium benzoate and loratadine-methylparaben-propylparaben mixtures.
Popović, Gordana   +2 more
core   +6 more sources

Transcriptomic Analysis of Loratadine as an Antibiotic Adjuvant Against MRSA [PDF]

open access: yes, 2023
Methicillin-resistant Staphylococcus aureus (MRSA) has evolved to become resistant to multiple classes of antibiotics. New antibiotics are costly to develop and deploy, and they have a limited effective lifespan.
Heather, Miller   +9 more
core   +2 more sources

Loratadine dysregulates cell cycle progression and enhances the effect of radiation in human tumor cell lines

open access: yesRadiation Oncology, 2010
Background The histamine receptor-1 (H1)-antagonist, loratadine has been shown to inhibit growth of human colon cancer xenografts in part due to cell cycle arrest in G2/M.
Cook John A   +5 more
doaj   +1 more source

Solubility and Physical Stability Enhancement of Loratadine by Preparation of Co-Amorphous Solid Dispersion with Chlorpheniramine and Polyvinylpyrrolidone

open access: yesPharmaceutics, 2023
Loratadine (LRD), a non-sedating and slow-acting antihistamine, is often given in combination with short-onset chlorpheniramine maleate (CPM) to increase efficacy. However, LRD has poor water solubility resulting in low bioavailability.
Krit Suknuntha   +3 more
doaj   +1 more source

DataSheet1_A systematic review and meta-analysis of loratadine combined with montelukast for the treatment of allergic rhinitis.PDF

open access: yes, 2023
Background: Loratadine and montelukast are clinical first-line drugs in the treatment of allergic rhinitis (AR). However, there is no clear evidence of the efficacy of loratadine combined with montelukast in the treatment of AR.
Li Tian (207552)   +3 more
core   +1 more source

Loratadine Combats Methicillin-Resistant Staphylococcus aureus by Modulating Virulence, Antibiotic Resistance, and Biofilm Genes

open access: yes, 2023
Methicillin-resistant Staphylococcus aureus (MRSA) has evolved to become resistant to multiple classes of antibiotics. New antibiotics are costly to develop and deploy, and they have a limited effective lifespan.
Owee K. Kirpekar (17708388)   +11 more
core   +3 more sources

Polarographic determination of loratadine in pharmaceutical preparations [PDF]

open access: yes, 1996
Loratadine, a potent antihistamine drug, is not directly electroreducible at a dropping mercury electrode; however, by means of a nitration procedure it is possible to obtain a nitro-loratadine derivative which has been identified as 4(8-chloro-7-nitro-5,
Squella Serrano, Juan   +9 more
core   +1 more source

Developmental Pharmacogenetics of CYP2D6 in Chinese Children: Loratadine as a Substrate Drug

open access: yesFrontiers in Pharmacology, 2021
Objective: The elucidation of CYP2D6 developmental pharmacogenetics in children has improved, however, these findings have been largely limited to studies of Caucasian children.
Qian Li   +12 more
doaj   +1 more source

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