Results 21 to 30 of about 6,251 (206)

A novel nasal co-loaded loratadine and sulpiride nanoemulsion with improved downregulation of TNF-α, TGF-β and IL-1 in rabbit models of ovalbumin-induced allergic rhinitis

open access: yesDrug Delivery, 2021
Purpose The work aimed to develop a co-loaded loratadine and sulpiride nasal nanoemulsion for allergic rhinitis management. Methods Compatibility studies were conducted adopting differential scanning calorimetry and Fourier transform infrared ...
Soad A. Mohamad   +5 more
doaj   +1 more source

Ginger extract versus Loratadine in the treatment of allergic rhinitis: a randomized controlled trial

open access: yesBMC Complementary Medicine and Therapies, 2020
Background Allergic rhinitis (AR) is a non-infectious immune disease and incidents of the disease has continuously increased in Thailand. Ginger, a Thai herb, is used in food and Thai traditional medicine.
Rodsarin Yamprasert   +3 more
doaj   +1 more source

The identification and the quantitative determination of loratadine by the HPLC method

open access: yesЖурнал органічної та фармацевтичної хімії, 2021
Aim. To develop the unified method of the HPLC analysis of loratadine, which can allow obtaining reliable and reproducible results of the studies of pharmaceuticals and biological matrices for monitoring the treatment effectiveness.
Olena O. Mamina   +3 more
doaj   +1 more source

The Effects of Combined Therapeutic Protocol on Allergic Rhinitis Symptoms and Molecular Determinants

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2022
Current medications to treat allergic rhinitis (AR) include antihistamines, corticosteroids, and anti-leukotrienes. In the present study, we investigated the effects of combination therapy; using these drugs, and evaluates the AR-related markers and ...
Yuanfeng Shen   +3 more
doaj  

IMPACT OF DIFFERENT EXCIPIENTS ON DISSOLUTION IMPROVEMENT OF LORATADINE BY SOLID DISPERSION

open access: yes, 2022
Loratadine is one of the most commonly used anti-histamine. It is practically insoluble in water. The onset of the action of the Loratadine is delayed due to its poor aqueous solubility.
Mohammed Raihan Chowdhury (11160018)
core   +1 more source

Loratadine Alleviates Advanced Glycation End Product-Induced Activation of NLRP3 Inflammasome in Human Chondrocytes

open access: yesDrug Design, Development and Therapy, 2020
Feng Gao,1 Shanyong Zhang2 1Department of Orthopedics, The Second Hospital of Jilin University, Changchun City, Jilin Province 130041, People’s Republic of China; 2Department of Spine Surgery, The Second Hospital of Jilin University, Changchun City,
Gao F, Zhang S
doaj  

The Effectiveness of Levocetirizine in Comparison with Loratadine in Treatment of Allergic Rhinitis —A Meta-Analysis

open access: yesAllergology International, 2011
Background: Oral antihistamines are considered the gold standard therapy for allergic rhinitis to date. The goal of this investigation is to make an indirect comparison between loratadine, an oral antihistamine available over-the-counter (OTC) in the USA,
Ralph Mösges   +2 more
doaj   +1 more source

Acupuncture Alleviates Allergic Rhinitis by Activating the AMPK/PGC‐1α Pathway to Attenuate Mitochondrial Oxidative Stress and Restore Epithelial Barrier Function

open access: yesFlavour and Fragrance Journal, EarlyView.
Acupuncture at Feishu (BL13), Shenshu (BL23), Yingxiang (LI20), and Dazhui (GV14) alleviates allergic rhinitis by activating the AMPK/PGC‐1α/NRF1/TFAM signalling axis. This activation improves mitochondrial biogenesis and function, reduces mtROS‐mediated oxidative stress, restores ATP production and respiratory complex I/IV activity, suppresses IgE and
Fengying Zhang   +3 more
wiley   +1 more source

Assessing satisfaction with desloratadine and fexofenadine in allergy patients who report dissatisfaction with loratadine

open access: yesBMC Family Practice, 2003
Background The FDA recently moved loratadine (Claritin) from prescription only status to over-the-counter (OTC). In response to the availability of an OTC non-sedating antihistamine, many managed care organizations are reevaluating which if any ...
Harper Anne S, Glass Daniel J
doaj   +1 more source

Neurological Adverse Effects Associated With Commonly Used H1‐Antihistamines: A Narrative Review of Age‐Stratified Risk Profiles in Paediatric and Geriatric Populations

open access: yesMedicine Advances, EarlyView.
This narrative review examines the neurological adverse effects associated with commonly used H1‐antihistamines, focusing on how blood–brain barrier (BBB) penetration and patient age influence central nervous system (CNS) toxicity. The major finding is that first‐generation antihistamines, because of higher CNS penetration, are associated with ...
Syeda Samia Fatima   +6 more
wiley   +1 more source

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