Results 171 to 180 of about 504,468 (237)

Progression of lumbar disc degeneration: A 14-year follow-up study examining Pfirrmann grading and its individual disc components. [PDF]

Acta Radiol Open
Murto N, Lund T, Kautiainen H, Luoma K, Kerttula L.   +4 more
europepmc   +1 more source

Affective Predictions in Chronic Pain: Differential Associations With Pain Interference and Intensity

European Journal of Pain, Volume 30, Issue 8, September 2026.
ABSTRACT Background Expectations have an important impact on emotion‐pain interactions. Previous studies have primarily focused on the influence of pain‐related expectations on perceived pain intensity. However, expectations regarding negative‐valence information more broadly may impact perception beyond pain and be altered when pain becomes chronic ...
Tal Ivancovsky, Salvatore Cajiao, Juan R. Castaño‐Asins, Antonio Montes‐Pérez, Eva Cortés‐Velasco, Juan V. Luciano, Lorena Chanes   +6 more
wiley   +1 more source

Age- and sex-related differences in lumbar disc degeneration and multifidus muscle atrophy: a retrospective MRI study of 238 patients with chronic low back pain. [PDF]

BMC Musculoskelet Disord
Tian M, Qi B, Zeng J, Chen J, Lin M.
europepmc   +1 more source

Association Between Conservative Treatment Modalities and Clinical Outcomes in Patients With Lumbosacral Disc Herniation Following Short Term and Long Term Treatments: A Retrospective Cohort Study

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Lumbar disc herniation (LDH), a leading cause of low back pain, necessitates effective conservative management to mitigate surgical interventions. This retrospective observational study evaluated the short‐term (6 months–2 years) and long‐term (3–6 years) efficacy of conservative therapies in 194 LDH patients from Iran ...
Bina Eftekharsadat, Shadi Khodaei, Raha Markazi‐Movaghar, Fatemeh ojaghlou, Azizeh Farshbaf‐Khalili, Soraya Babaie   +5 more
wiley   +1 more source

Association between lumbar disc degeneration at L4-L5 level and atrophy of paraspinal muscles and gluteus medius: a cross-sectional study using 3T quantitative magnetic resonance imaging. [PDF]

BMC Med Imaging
Wen Q, Wang J, Tan G, Huang Y, Wang H, Ding X, Liu K, Zhang Y, Tan W.   +8 more
europepmc   +1 more source

A Standardized Perioperative Care Program and Postoperative Pain, Disability, and Knowledge Among Patients Undergoing Lumbar Spine Surgery in Erbil, Iraq: A Non‐Randomized Controlled Study

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aim Patients recovering from lumbar spine surgery frequently report persistent pain, functional limitation, and limited understanding of postoperative self‐care. This study examined whether participation in a standardized perioperative care program was associated with differences in pain, functional disability, and patient ...
Vian Afan Naqshbandi, Sideeq Sadir Ali, Nuraddin Hamad Mhammad, Abdulmalik Fareeq Saber   +3 more
wiley   +1 more source

Presence of sacralized lumbar vertebra predisposes to adjacent level lumbar disc degeneration: A cross-sectional study. [PDF]

Acta Orthop Traumatol Turc
Bayram S, Altin YF, Kahraman A, Yağci TF, Korkmaz M, Akgül T.   +5 more
europepmc   +1 more source

Juanbi Tang Attenuates Intervertebral Disc Degeneration by Suppressing p38MAPK/NF‐κB Signaling and Activating Atg5‐Dependent Autophagy to Promote Macrophage M2 Polarization: In Vivo and In Vitro Evidence

Immunity, Inflammation and Disease, Volume 14, Issue 9, September 2026.
Graphical Abstract. Juanbi Tang (JBT) suppresses the p38MAPK/NF‐κB signaling pathway in disc‐infiltrating macrophages, simultaneously activating Atg5‐dependent autophagy. Autophagic degradation of p62/SQSTM1 consolidates NF‐κB inhibition through an autophagy–p62–NF‐κB regulatory module, facilitating macrophage M1‐to‐M2 polarization.
Ye‐Hui Wang, Wei Hou, Guo‐Sheng Tang, Xuan‐Geng Deng, Si‐Mao Song, Wei Cui, Yang Ye, Yang Yu   +7 more
wiley   +1 more source

Cell-Free Fat Extract for the Treatment of Lumbar Disc Degeneration: A Novel Approach Using Adipose-Derived Biologic. [PDF]

Biomedicines
Xu C, Zhou X, Yang C, Zhou F, Xie Y.
europepmc   +1 more source

Neural Stem Cell‐Derived Extracellular Vesicles Improve CNS Delivery and Therapeutic Efficacy of Antisense Oligonucleotide in Amyotrophic Lateral Sclerosis

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
Passive ASO association with NSC‐EVs enhances neuronal uptake and CNS accumulation. NSC‐EV‐ASOs suppress pathogenic targets in ALS cellular models and, following intranasal administration, delay disease onset and improve motor function in SOD1‐G93A mice. These findings provide proof‐of‐concept evidence supporting NSC‐EVs as a platform for enhancing CNS
Yaochao Zheng, Taylor Jade Ellison, Robert Garrard, Jinghui Gao, Xinning Lai, Lin Lan, Jin Xie, Jie Jiang, Yao Yao   +8 more
wiley   +1 more source