Results 11 to 20 of about 3,794 (236)

Amaryllidaceae Alkaloids and Phenolic Acids Identification in Leucojum aestivum L. Plant Cultures Exposed to Different Temperature Conditions [PDF]

Molecules
Amaryllidaceae alkaloids are of notable pharmacological relevance. For instance, galanthamine is used in the treatment of Alzheimer’s disease, while other alkaloids (lycorine, crinine, etc.) derived from Amaryllidaceae plants are also of great interest ...
Agata Ptak, Marzena Warchoł, Emilia Morańska, Dominique Laurain-Mattar, Rosella Spina, François Dupire, Piotr Waligórski, Magdalena Simlat   +7 more
doaj   +2 more sources

Application of HPLC-DAD for the quantification of Lycorine in Galanthus elwesii Hook [PDF]

Brazilian Journal of Pharmaceutical Sciences, 2017
In the present study, a reversed-phase high-performance liquid chromatographic method has been used for the quantitative determination of lycorine in the aerial parts and bulbs of G. elwesii Hook.
Ahmet Emir, Ceren Emir, Buket Bozkurt, Mustafa Ali Onur, Nehir Unver Somer, Gulen Irem Kaya   +5 more
doaj   +2 more sources

Lycorine inhibits glioblastoma multiforme growth through EGFR suppression [PDF]

Journal of Experimental & Clinical Cancer Research, 2018
Background Lycorine has been revealed to inhibit the development of many kinds of malignant tumors, including glioblastoma multiforme (GBM). Although compelling evidences demonstrated Lycorine’s inhibition on cancers through some peripheral mechanism, in-
Jia Shen, Tao Zhang, Zheng Cheng, Ni Zhu, Hua Wang, Li Lin, Zexia Wang, Haotian Yi, Meichun Hu   +8 more
doaj   +3 more sources

Up-regulation of p21 and TNF-α is mediated in lycorine-induced death of HL-60 cells [PDF]

Cancer Cell International, 2010
Background Leukemia is one of the most life-threatening cancers today, and acute promyelogenous leukemia (APL) is a common type of leukemia. Many natural compounds have already been found to exhibit significant anti-tumor effects.
He Yan, Shi Bi-Wei, Hu Ji-liang, Liu Jing, Hu Wei-Xin   +4 more
doaj   +5 more sources

Apoptosis Induction of Lycorine on Lung Cancer NCI-H460 Cells and Related Mechanism

Zhongliu Fangzhi Yanjiu, 2018
Objective To investigate the effect of lycorine on the proliferation inhibition and apoptosis induction in human lung cancer NCI-H460 cells, and to explore the anti-tumor mechanism of lycorine.
LI Juwei, YANG Yang
doaj   +2 more sources

Exploring the safety of lycorine in the central nervous system and its impact on pain-like behaviors in mice [PDF]

Scientific Reports
Alkaloid analgesics have been associated with adverse effects on the central nervous system (CNS). Therefore, it is crucial to characterize the effects of alkaloid analgesics.
Hasriadi Hasriadi, Peththa Wadu Dasuni Wasana, Wisuwat Thongphichai, Suchada Sukrong, Pasarapa Towiwat   +4 more
doaj   +2 more sources

Lycorine affects tamoxifen resistance of breast cancer via m⁶A-based HAGLR. [PDF]

Transl Cancer Res
Shi L, Jiang JF, Zhai J.
europepmc   +2 more sources

Lycorine Pre-Treatment Alleviates Microglia Inflammation After Cerebral Ischemia by Inhibiting NF-κB Phosphorylation [PDF]

Brain Sciences
Background: Middle-aged and elderly individuals may experience detrimental health effects due to ischemic stroke (IS). The inflammatory response triggered during IS exacerbates neuronal damage, becoming a barrier to effective IS treatment and leading to ...
Wuyan Zheng, Wanyu Wu, Yuhan Li, Bo Qin, Yuping Wang, Yunhan Zeng, Betty Yuen Kwan Law, Vincent Kam Wai Wong   +7 more
doaj   +2 more sources

Retraction: Lycorine displays potent antitumor efficacy in colon carcinoma by targeting STAT3. [PDF]

Front Pharmacol
Frontiers Editorial Office.
europepmc   +3 more sources

Lycorine hydrochloride inhibits cholangiocarcinoma through cholesterol biosynthesis and PTPN11 nuclear translocation. [PDF]

Cell Commun Signal
Zhao F, Peng S, Zou L, Zhong M, Huang Y, Wang P, Ji M, Ma X, Li F.   +8 more
europepmc   +3 more sources