Two new alkaloids from Narcissus serotinus L. [PDF]
, 2010 The Amaryllidaceae family is well known for the presence of an exclusive group of alkaloids with a wide range of biological activities. Narcissus serotinus L.
Bastida Armengol, Jaume +6 more
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Effect of lycorine on the structure and function of hepatoma cell membrane in vitro and in vivo
Biotechnology & Biotechnological Equipment, 2020 Lycorine is an isoquinoline alkaloid in Amaryllidaceae with antitumor, antibacterial, antiviral, diuretic and cardiovascular effects. This study explored the antitumor mechanism of lycorine in vitro and in vivo by focusing on its effects on tumor cell ...
Guosong Xin +8 more
doaj +1 more source
Elucidating the enzyme network driving Amaryllidaceae alkaloids biosynthesis in Leucojum aestivum. [PDF]
Plant Biotechnol JSchematic representation of Amaryllidaceae alkaloid biosynthesis in Leucojum aestivum. Norbelladine synthase (LaNBS) and noroxomaritidine/norcraugsodine reductase (LaNRII) catalyze the condensation of tyramine and 3,4‐dihydroxybenzaldehyde to form norbelladine, which is subsequently O‐methylated by norbelladine‐4′‐O‐methyltransferase (LaN4′OMT ...
Lamichhane B +6 more
europepmc +2 more sources
Image Guided Biodistribution of Drugs and Drug Delivery [PDF]
, 2012 Image guided technique is playing an increasingly important role in the investigation of the biodistribution and pharmacokinetics of drugs or drug delivery systems.
Ding, Hong, Wu, Fang
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Identification of Alkaloids from Hippeastrum aulicum (Ker Gawl.) Herb.(Amaryllidaceae) Using CGC-MS and Ambient Ionization Mass Spectrometry (PS-MS and LS-MS) [PDF]
, 2017 Amaryllidaceae alkaloids are well-known isoquinolines which have demonstrated a wide range of biological activities such as antiviral, anticancer, acetylcholinesterase inhibition, antimalarial, among others.
Andrade, Jean Paulo de +7 more
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Alkaloid Compound Identification of Rhodomyrtus Tomentosa Stem as Biology Instructional Material for Senior High School X Grade [PDF]
, 2016 Rhodomyrtus tomentosais one of herbs which belongs to myrtaceaefamily. This plant possessesalkaloid which is efficacious as anti diarrhea, anti diabetes, anti microbial, and anti malaria, however some alkaloid compoundsare poisonous. Thus,it is necessity
Ningrum, R. (Retno) +2 more
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Lycorine induces cell-cycle arrest in the G0/G1 phase in K562 cells via HDAC inhibition
Cancer Cell International, 2012 Background Lycorine, a natural alkaloid extracted from Amaryllidaceae, has shown various pharmacological effects. Recent studies have focused on the potential antitumor activity of lycorine. In our previous study, we found that lycorine decrease the cell
Li Lv +8 more
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ERK Inhibition Promotes Engraftment of Allografts by Reprogramming T‐Cell Metabolism
Advanced Science, 2023 Extracellular regulated protein kinases (ERK) signaling is a master regulator of cell behavior, life, and fate. Although ERK pathway is shown to be involved in T‐cell activation, little is known about its role in the development of allograft rejection ...
Xiaosheng Tan +15 more
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Horticulturae, 2023 Lycorine is an important Amaryllidaceae alkaloid showing anti-cancerous activity on numerous cell lines; and it also demonstrates antiviral activity against several viruses including SARS-CoV-2 responsible for COVID-19.
Rukaya Syeed +8 more
doaj +1 more source
Kaohsiung Journal of Medical Sciences, 2023 Much is known about the significance of lycorine, a natural alkaloid, in combating various types of cancer, including breast cancer (BC), but whether it participates in regulating tamoxifen (TAM) resistance and its underlying mechanism remain to be ...
Jing Zhai, Jun‐Feng Jiang, Lei Shi
doaj +1 more source