Results 111 to 120 of about 34,914 (256)
Systemic and local decorin levels mirror the clinical course of pancreatic cancer
Abstract Despite significant progress in oncology research, pancreatic cancer remains inherently difficult to treat, and the mechanisms underlying therapeutic resistance remain unresolved. Decorin (DCN), a member of the family of small leucine‐rich proteoglycans, has emerged as a versatile actor in various malignant diseases.
Maja Svensson +6 more
wiley +1 more source
ABSTRACT Objective Cognitive impairment (CI) affects the quality of life in multiple sclerosis (MS). Identifying influencing factors is key to improving CI monitoring. This systematic review and meta‐analysis examines clinical and sociodemographic variables impacting the cognitive screening Symbol Digit Modalities Test (SDMT) performance across MS ...
Katalin Lugosi +8 more
wiley +1 more source
CD30 as a Target Molecule in the Diagnosis and Therapy of Lymphomas
ABSTRACT The tumor necrosis factor (TNF)‐receptor superfamily 8 receptor CD30 molecule is expressed in all tumor cells of Hodgkin lymphoma and anaplastic large cell lymphoma but is only weakly expressed in a small subset of large lymphoid cells in normal peripheral lymphoid tissues.
Harald Stein, Brunangelo Falini
wiley +1 more source
A novel pathogenic MLH1 missense mutation, c.112A > C, p.Asn38His, in six families with Lynch syndrome [PDF]
E. van Riel +12 more
openalex +1 more source
Silk Fibroin‐Stabilized Lapachol Microemulsion Enhances Antiglioma Activity In Vitro
Silk fibroin‐stablized lapachol microformulation antiglioma activity. ABSTRACT Gliomas are the most prevalent of the brain tumors, and are associated with high mortality and limited therapeutic options. This study introduces, for the first time, a silk fibroin (SF)‐based microemulsion as a nanocarrier for lapachol (LP).
Jardel P. Queiroz +10 more
wiley +1 more source
Bevacizumab in ovarian cancer: Clinical data and predictive and prognostic biomarkers
Evidence supporting bevacizumab in ovarian cancer and predictive biomarkers: highlighting opportunities to improve patient selection and advance personalised treatment strategies. Abstract Angiogenesis, driven by the vascular endothelial growth factor (VEGF)/VEGFR signalling axis under hypoxic conditions, is one of the hallmarks of ovarian cancer (OC),
Maria Rosaria Lamia +6 more
wiley +1 more source
1526 Nous-209 genetic vaccine encoding shared cancer neoantigens is safe and elicits robust immune response in healthy Lynch syndrome carriers: interim results from Phase 1 cancer interception trial [PDF]
Morena D’Alise +21 more
openalex +1 more source
ABSTRACT Hippocampal Area CA2, with some exceptions, had long been neglected in in vivo studies, due largely to its small size, and in in vitro studies because of its general similarity to CA3 and CA1. Increasing evidence showing that CA2 was molecularly distinct led to the increased appreciation of CA2 as a separate region, and as such, that it likely
Serena M. Dudek
wiley +1 more source
Endoscopic full thickness resection for early colon cancer in Lynch syndrome [PDF]
Alexandra M. J. Langers +5 more
openalex +1 more source

