Results 1 to 10 of about 76,328 (190)

Targeting lysine acetylation readers and writers. [PDF]

Nat Rev Drug Discov
Lysine acetylation is a major post-translational modification in histones and other proteins that is catalysed by the 'writer' lysine acetyltransferases (KATs) and mediates interactions with bromodomains (BrDs) and other 'reader' proteins. KATs and BrDs play key roles in regulating gene expression, cell growth, chromatin structure, and epigenetics and ...
Zhou MM, Cole PA.
europepmc   +3 more sources

Protein lysine acetylation regulates oral microorganisms. [PDF]

Front Cell Infect Microbiol
Post-translational modifications (PTMs) are integral to the regulation of protein function, stability, and cellular processes. Lysine acetylation, a widespread PTM, has been extensively characterized for its role in eukaryotic cellular functions, particularly in metabolism, gene expression, and disease progression.
Yang Y, He H, Liu B, Li Z, Sun J, Zhao Z, Yang Y.   +6 more
europepmc   +3 more sources

Systematic proteomics analysis of lysine acetylation reveals critical features of renal proteins in kidney calculi formation. [PDF]

PLoS One
Zhang S, Wang Z, Jiang H, Wang J, Jin M, Liang H, Deng Q.   +6 more
europepmc   +1 more source

Dynamic lysine acetylation and succinylation of platelet proteins regulates platelet storage lesion: mechanistic insights from multi-omics. [PDF]

Ann Med
Liao X, Zhang C, Chen M, Zhou J, Luo X, Zhang Y, Hu X, Wang Z, Wang L.   +8 more
europepmc   +1 more source

Integration of ploidy, Orc1/Cdc6 homolog function, and lysine acetylation with phosphate limitation and UV stress responses of Haloferax volcanii. [PDF]

Extremophiles
Gal D, Smith C, Cooper K, Couto-Rodríguez RL, Maupin-Furlow JA.   +4 more
europepmc   +1 more source

Nicotinamide mononucleotide treatment improves spermatogenesis in obese mice by reducing lysine acetylation of lactate dehydrogenase C. [PDF]

Commun Biol
Liu K, Nong W, Huang H, Wei Y, Wang J, Youzhu L, Huang G, Tang Z, Yu J, Huo P, Hu L, Chen X, Wang X, Lei X.   +13 more
europepmc   +1 more source

Role of lysine acetylation-related genes in the diagnosis and prognosis of glioma. [PDF]

Sci Rep
Zhou M, Wang B, Liang R, Luan X.
europepmc   +1 more source

MSTL-Kace: Prediction of Prokaryotic Lysine Acetylation Sites Based on Multistage Transfer Learning Strategy. [PDF]

ACS Omega, 2023
Wang GA, Yan X, Li X, Liu Y, Xia J, Zhu X.   +5 more
europepmc   +1 more source

DNA Polymerase Delta Exhibits Altered Catalytic Properties on Lysine Acetylation. [PDF]

Genes (Basel), 2023
Njeri C, Pepenella S, Battapadi T, Bambara RA, Balakrishnan L.   +4 more
europepmc   +1 more source

NAD⁺-Dependent Lysine Acetylation Regulates Glucose Uptake and Fatty Acid Oxidation in Cardiomyocytes. [PDF]

Metabolites
Vanni E, Montessuit C.
europepmc   +1 more source