Results 11 to 20 of about 76,328 (190)
SPOTing Acetyl-Lysine Dependent Interactions [PDF]
Microarrays, 2015 Post translational modifications have been recognized as chemical signals that create docking sites for evolutionary conserved effector modules, allowing for signal integration within large networks of interactions. Lysine acetylation in particular has attracted attention as a regulatory modification, affecting chromatin structure and linking to ...
Picaud, Sarah, Filippakopoulos, Panagis
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Characterizing lysine acetylation of glucokinase. [PDF]
Protein Sci, 2023 AbstractGlucokinase (GK) catalyzes the phosphorylation of glucose to form glucose‐6‐phosphate as the substrate of glycolysis for energy production. Acetylation of lysine residues in Escherichia coli GK has been identified at multiple sites by a series of proteomic studies, but the impact of acetylation on GK functions remains largely unknown.
Fatema N, Li X, Gan Q, Fan C.
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Bromodomain: an acetyl‐lysine binding domain [PDF]
FEBS Letters, 2002 Bromodomains, an extensive family of evolutionarily conserved protein modules originally found in proteins associated with chromatin and in nearly all nuclear histone acetyltransferases, have been recently discovered to function as acetyl‐lysine binding domains.
Zeng, Lei, Zhou, Ming-Ming
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Lysine acetylation modulates mouse sperm capacitation [PDF]
Scientific Reports, 2018 AbstractMammalian sperm are unable to fertilize the egg immediately after ejaculation. To gain fertilization competence, they need to undergo a series of modifications inside the female reproductive tract, known as capacitation. Capacitation involves several molecular events such as phosphorylation cascades, hyperpolarization of the plasma membrane and
Ritagliati, Carla +5 more
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Protein Lysine Acetylation by p300/CBP [PDF]
Chemical Reviews, 2015 Since their discovery in the 1980s and 1990s, the human protein lysine acetyltransferase encoded by the paralogous p300 and CBP genes has received much interest. p300/CBP functions in regulating the expression of genes controlling several basic cellular processes, such as proliferation and homeostasis, and plays a role in a variety of human diseases ...
Dancy, Beverley M., Cole, Philip A.
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Modulation of plant acetyl-CoA synthetase activity by post-translational lysine acetylation. [PDF]
Front Mol Biosci, 2023 Acetyl-CoA synthetase (ACS) is one of several enzymes that generate the key metabolic intermediate, acetyl-CoA. In microbes and mammals ACS activity is regulated by the post-translational acetylation of a key lysine residue. ACS in plant cells is part of a two-enzyme system that maintains acetate homeostasis, but its post-translational regulation is ...
Sofeo N +3 more
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The Cardiac Acetyl-Lysine Proteome
PLoS ONE, 2013 In the heart, lysine acetylation has been implicated in processes ranging from transcriptional control of pathological remodeling, to cardioprotection arising from caloric restriction. Given the emerging importance of this post-translational modification, we used a proteomic approach to investigate the broader role of lysine acetylation in the heart ...
D Brian Foster +6 more
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Proteomics profiling asthma induced-lysine acetylation
EXCLI journal, 2020 EXCLI Journal;Vol.
Su, Xin-ming +6 more
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Lysine acetylation in cyanobacteria: emerging mechanisms and functions. [PDF]
Biochem Soc TransCyanobacteria are ancient and abundant photosynthetic prokaryotes that play crucial roles in global carbon and nitrogen cycles. They exist in a variety of environments and have been used extensively as model organisms for studies of photosynthesis and environmental adaptation.
Liu X, Yang M, Ge F, Zhao J.
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Abnormal lysine acetylation with postovulatory oocyte aging [PDF]
Reproductive Medicine and Biology, 2013 AbstractBackgroundA postovulatory mammalian oocyte decreases developmental potential with in vivo aging in the oviduct or in vitro aging in the culture dish. The mechanism underlying oocyte aging still largely remains an enigma. Accumulating data suggest that the epigenetic alterations such as histone acetylation are also associated with postovulatory ...
Ah Reum, Lee +3 more
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