Results 181 to 190 of about 11,326 (215)

Recent research advances in RNA m5C methylation modification in liver diseases. [PDF]

Front Mol Biosci
Chen W, Zhang L, Gu X, Liu Y, Zhang S, Hu X, Li P.   +6 more
europepmc   +1 more source

RNA 5-Methylcytosine Modification in Myocardial Fibrosis. [PDF]

Rev Cardiovasc Med
Li B, Hao Y, Tian W, Liu W.
europepmc   +1 more source

Study of m5C as a regulator of mRNA stability

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mRNA m5C inhibits adipogenesis and promotes myogenesis by respectively facilitating YBX2 and SMO mRNA export in ALYREF-m5C manner

Cellular and Molecular Life Sciences, 2022
Although 5-methylcytosine (m5C) has been identified as a novel and abundant mRNA modification and associated with energy metabolism, its regulation function in adipose tissue and skeletal muscle is still limited. This study aimed at investigating the effect of mRNA m5C on adipogenesis and myogenesis using Jinhua pigs (J), Yorkshire pigs (Y) and their ...
Ruifan Wu, Xinxia Wang
exaly   +3 more sources

Staem5: A novel computational approach for accurate prediction of m5C site [PDF]

Molecular Therapy - Nucleic Acids, 2021
5-Methylcytosine (m5C) is an important post-transcriptional modification that has been extensively found in multiple types of RNAs. Many studies have shown that m5C plays vital roles in many biological functions, such as RNA structure stability and metabolism.
Cang-Zhi Jia, Quan Zou, Fuyi Li
exaly   +5 more sources

Emerging Role of RNA m5C Modification in Cardiovascular Diseases

Journal of Cardiovascular Translational Research, 2022
Epitranscriptomics is the emerging field of research that comprises the study of epigenetics changes in RNAs. Progressing development in the field of epigenetics has helped to manage and comprehend human diseases. RNA methylation regulates all aspects of RNA functions, which are involved in the pathogenesis of human diseases.
Kannan, Balachander, Jayaseelan Vijayashree, Priyadharsini, Anitha, Roy, Arumugam, Paramasivam   +3 more
openaire   +2 more sources

mRNA m5C controls adipogenesis by promoting CDKN1A mRNA export and translation

RNA Biology, 2021
5-Methylcytosine (m5C) is a type of RNA modification that exists in tRNAs and rRNAs and was recently found in mRNA. Although mRNA m5C modification has been reported to regulate diverse biological process, its function in adipogenesis remains unknown.
Ruifan Wu, Xinxia Wang
exaly   +3 more sources

m5C mRNAs on the move

Nature Reviews Molecular Cell Biology, 2019
Cytosine methylation (m5C) in mRNAs is important for their transport to distant tissues in plants.
exaly   +3 more sources

Trans-m5C: A transformer-based model for predicting 5-methylcytosine (m5C) sites

Methods
5-Methylcytosine (m5C) plays a pivotal role in various RNA metabolic processes, including RNA localization, stability, and translation. Current high-throughput sequencing technologies for m5C site identification are resource-intensive in terms of cost, labor, and time. As such, there is a pressing need for efficient computational approaches.
Fu, Haitao, Ding, Zewen, Wang, Wen
exaly   +4 more sources