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RNA methylation and breast cancer: insights into m6A, m7G and m5C

Molecular Biology Reports
Breast cancer remains the most commonly diagnosed cancer in female worldwide, marked by its molecular diversity and complex subtypes. Despite progress in targeted therapies, tumor heterogeneity and treatment resistance continue to present major challenges. Recent studies emphasize the crucial role of RNA modifications in cancer biology, with nearly 200
Yuhan, Dai   +6 more
openaire   +2 more sources

The Role of RNA m5C Modification in Central Nervous System Diseases

Discovery Medicine
As advances in RNA modification research progress, the significance of 5-methylcytosine (m5C) modification is being increasingly acknowledged. m5C undergoes modification by the methyltransferase NOP2/Sun domain (NSUN) family/DNA methyltransferase (DNMT) family (writer) and is removed by demethylases (eraser), including the ten-eleven translocation (TET)
Peiyan, Wu   +3 more
openaire   +2 more sources

Identification of Human RNA m5C sites using CapsuleNet Architecture

2022 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), 2022
Mobeen Ur Rehman   +2 more
openaire   +1 more source

FMRP promotes transcription-coupled homologous recombination via facilitating TET1-mediated m5C RNA modification demethylation

Proceedings of the National Academy of Sciences of the United States of America, 2022
Haibo Yang, Yumin Wang, Yufei Xiang
exaly  

Vital roles of m5C RNA modification in cancer and immune cell biology

Frontiers in Immunology, 2023
, Haihong Zhu, Gu Xinyu
exaly  

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