Results 141 to 150 of about 21,524 (239)

m6A mRNA methylation sustains Treg suppressive functions [PDF]

Cell Research, 2018
Jiyu, Tong, Guangchao, Cao, Ting, Zhang, Esen, Sefik, Maria Carolina, Amezcua Vesely, James P, Broughton, Shu, Zhu, Huabin, Li, Bin, Li, Lei, Chen, Howard Y, Chang, Bing, Su, Richard A, Flavell, Hua-Bing, Li   +13 more
openaire   +2 more sources

The crucial role of m6A methylation modification in nasopharyngeal carcinoma. [PDF]

Discov Oncol
Jin L, Song J.
europepmc   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

RNA m6A methylation fine-tunes the jasmonic acid biosynthesis pathway to modulate plant aging. [PDF]

Plant Cell
Zhang Y, Li P, Hua C, Ma J, Kong KN, Zhang S, Wu X, Loi J, Choi IKY, He C, Jang IC, Shen L.   +11 more
europepmc   +1 more source

Patterns of Drug Resistance, Drug Resistance Conferring Mutations and Genomic DNA Methylation Revealed in Mycobacterium tuberculosis From South Africa

Tropical Medicine &International Health, EarlyView.
ABSTRACT Tuberculosis remains a major public health threat globally, with drug‐resistant strains undermining treatment efficacy. We analyzed 126 Mycobacterium tuberculosis (M. tuberculosis) isolates with diverse drug resistance spectra and selected 35 for whole genome sequencing (WGS) using Illumina NextSeq, SMRT PacBio Onso and SMRT PacBio Revio ...
Unarine Matodzi, Awelani Mutshembele, Eric Mensah, Dillon Muzondiwa, Ndivhuho A. Makhado, Oleg N. Reva   +5 more
wiley   +1 more source

IDH1-Associated m6A Methylation Is Linked to Transcriptomic Heterogeneity in Glioma. [PDF]

Cancers (Basel)
Batool SM, Lee H, Muralidharan K, Khan SM, Escobedo AK, Gashi D, Faber K, Barretts NR, Ekanayake E, Hsia T, Al-Inaya Y, Kosgi A, Miller JJ, Cahill DP, Dunn GP, Choi BD, Petti AA, Carter BS, Balaj L.   +18 more
europepmc   +1 more source

Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities

The Journal of Physiology, EarlyView.
Abstract figure legend Hypoxia and hypercapnia cause overlapping skeletal muscle phenotypes, including atrophy, change in myofibre metabolic profile and myogenic response to injury. Both signals operate via distinct cellular pathways. Abstract Skeletal muscle dysfunction is strongly associated with elevated mortality in acute and chronic pulmonary ...
Joseph Balnis, Ariel Jaitovich
wiley   +1 more source

KIAA1429 knockdown alleviates osteosarcoma  progression by destabilizing SLC7A11 mRNA via m6A methylation to promote ferroptosis. [PDF]

Int J Oncol
Zeng H, Zhong Y, Zeng D, Xiao S, Zou S.
europepmc   +1 more source

The novel regulatory influence of Argonaute 1 on messenger RNA 5‐methylcytosine modification in Arabidopsis thaliana

The Plant Genome, Volume 19, Issue 4, December 2026.
Abstract 5‐Methylcytidine (m5C) modifications play a critical role in RNA metabolism. TRM4B (tRNA‐specific methytransferase 4B) is the only known component of the plant m5C machinery that mediates mRNA (messenger RNA) methylation. To date, no regulators governing site‐specific m5C modifications have been identified, apart from several degenerated ...
Zedi Feng, Xiu Yin, Zhifang Jiang, Jia Yao, Yiling Dong, Xiaoxia Ma, Yijun Meng   +6 more
wiley   +1 more source

Bone Marrow Mesenchymal Stem Cells Rescue Tendon Injury by Regulating FTO-Mediated m6A Methylation of ELOB. [PDF]

J Biochem Mol Toxicol
Dai ZR, Luo GH, Xie YQ.
europepmc   +1 more source