Results 141 to 150 of about 23,657 (254)

Prostate Cancer Development, Progression, and Therapy

MedComm – Oncology, Volume 5, Issue 3, September 2026.
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin, Zicheng Xiao, Zexian Ding, Wei Li, Ruijiang Zeng, Yujun Shuai, Weimin Ci, Dan Xia, Xu Zhang, Haojie Huang   +9 more
wiley   +1 more source

METTL3 inhibition alleviates neuroinflammation and apoptosis by reducing ETV4 m6A modification. [PDF]

Front Immunol
He D, Jiang X, Guo G, Ma J, Chen J, Zhang Y, Zhuang J, Xie P, Zhang Z.   +8 more
europepmc   +1 more source

Deciphering the Functional Mechanisms of eIF3f in Tumors and Exploring Targeted Therapies

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Eukaryotic translation initiation factor 3 subunit F (eIF3f) is a critical component of the eIF3 complex and plays a pivotal role in diverse biological processes, including cell proliferation, apoptosis, adhesion, and transcriptional regulation.
Yujinpeng Hao, Jun Shao, Naqi Lian, Mianli Bian   +3 more
wiley   +1 more source

m6A modification on ncRNAs and underlying mechanisms of exercise in the regulation of pathological cardiac remodeling. [PDF]

Eur J Med Res
Yin G, He X, Chen N.
europepmc   +1 more source

Mechanisms of Resistance, Insights From Case Reports, and Future Prospects in Mycobacteriophage Therapy

Journal of the Royal Society of New Zealand, Volume 56, Issue 4, August 2026.
Evolution of drug‐resistant mycobacterial infections warrants renewed efforts in identifying more efficient preventive and control strategies as well as alternative treatment options. Interest in phage therapy is regaining significant traction, especially in cases of failed conventional therapy.
Buhari Yusuf, Abdul Malik, Md Shah Alam, Lijie Li, Haftay Abraha Tadesse, Aweke Mulu Belachew, Cuiting Fang, Xirong Tian, Htin Lin Aung, Shuai Wang, Tianyu Zhang   +10 more
wiley   +1 more source

Research progress on the characteristics and functions of m6A modification in lung cancer tumor stem cells. [PDF]

Am J Cancer Res
Jiang G, Sun X, Wang F, Li Y, Liu X, Sun P.   +5 more
europepmc   +1 more source

Tumor‐educated platelets in cancer diagnostics and prognostics: A critical appraisal and roadmap for clinical translation

International Journal of Cancer, Volume 159, Issue 2, Page 302-319, 15 July 2026.
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon, Min‐Kyung Lee, Eunyong Ahn, Heeyeon Kim, Yong Sang Song, Taejin Ahn   +5 more
wiley   +1 more source

Genetic Variations in the M6A Modification Pathway as Potential Predictors of Imatinib Secondary Resistance in Gastrointestinal Stromal Tumors. [PDF]

J Clin Med
Zhou B, Chen Z, Zhang G, Guan S, Zhuang W, Huang M, Qiu H, Wang X.   +7 more
europepmc   +1 more source

Development of Quorum Sensing Modulators of Streptococcus constellatus

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
Using a rational design approach, novel Streptococcus constellatus competence stimulating peptide (CSP) analogs with enhanced potencies were developed. These newly identified CSP analogs provide a rational framework for the development of CSP‐based quorum sensing modulators with translational potential in attenuating virulence processes in this ...
Keely M. Rodriguez, Daniel N. Elliott, Ella R. Lemieux, Oscar S. Liu, Yftah Tal‐Gan   +4 more
wiley   +1 more source

Molecular mechanism of RBM15-mediated m6A modification in hepatitis B virus replication. [PDF]

Virol J
Ni M, Li B, Wang L, Ma S, Ma K.
europepmc   +1 more source