Results 91 to 100 of about 4,884 (228)
Efficient chromosomal-scale DNA looping in Escherichia coli using multiple DNA-looping elements [PDF]
, 2017 Genes are frequently regulated by interactions between proteins that bind to the DNA near the gene and proteins that bind to DNA sites located far away, with the intervening DNA looped out.
Dodd, I. +3 more
core +2 more sources
Differential management of the replication terminus regions of the two Vibrio cholerae chromosomes during cell division. [PDF]
PLoS Genetics, 2014 The replication terminus region (Ter) of the unique chromosome of most bacteria locates at mid-cell at the time of cell division. In several species, this localization participates in the necessary coordination between chromosome segregation and cell ...
Gaëlle Demarre +6 more
doaj +1 more source
High-Throughput Activity Assay for Screening Inhibitors of the SARS-CoV-2 Mac1 Macrodomain
bioRxiv, 2021 Macrodomains are a class of conserved ADP-ribosylhydrolases expressed by viruses of pandemic concern, including coronaviruses and alphaviruses. Viral macrodomains are critical for replication and virus-induced pathogenesis; therefore, these enzymes are a
Morgan Dasovich +14 more
semanticscholar +1 more source
Prokaryotic defense systems: Diversity and evolutionary adaptation
mLife, Volume 5, Issue 1, Page 3-16, February 2026.Abstract Bacteriophages and archaeal viruses are the most abundant biological entities on Earth. Through a long‐standing co‐evolutionary arms race, they have driven the emergence of a diverse repertoire of prokaryotic defense systems. This review summarizes these systems, highlighting their diverse antiviral mechanisms across distinct stages of viral ...
Changjialian Yang +3 more
wiley +1 more source
Magnetostrictive hysteresis of TbCo/CoFe multilayers and magnetic domains
, 2005 Magnetic and magnetostrictive hysteresis loops of TbCo/CoFe multilayers under field applied along the hard magnetization axis are studied using vectorial magnetization measurements, optical deflectometry and magneto optical Kerr microscopy.
A. Thiaville +10 more
core +2 more sources
ITM2B Truncation Promotes Migrasome Formation to Accelerate Renal Cell Carcinoma Growth
Advanced Science, Volume 13, Issue 4, 19 January 2026.This study identifies truncated ITM2B as a regulator of migrasome formation in renal cell carcinoma (RCC) cells. The ITM2B truncation not only facilitates migrasome formation by recruiting TSPAN4, but also sorts active caspase‐7 into migrasomes. The internalization of active caspase‐7‐enriched migrasomes by macrophages stimulates IL‐6 secretion to ...
Qi‐tao Chen +10 more
wiley +1 more source
The macrodomain family: Rethinking an ancient domain from evolutionary perspectives [PDF]
Chinese Science Bulletin, 2013 The reasons why certain domains evolve much slower than others is unclear. The notion that functionally more important genes evolve more slowly than less important genes is one of the few commonly believed principles of molecular evolution. The macro-domain (also known as the X domain) is an ancient, slowly evolving and highly conserved structural ...
Li, XiaoLei, Wu, ZhiQiang, Han, WeiDong
openaire +2 more sources
Microbiology Spectrum, 2023 Chikungunya virus (CHIKV) hijacks host cell machinery to support its replication. Nucleophosmin 1 (NPM1/B23), a nucleolar phosphoprotein, is one of the host proteins known to restrict CHIKV infection; however, the mechanistic details of the antiviral ...
Parvanendhu Pradeep +2 more
doaj +1 more source
Journal of the American Ceramic Society, Volume 109, Issue 1, January 2026.In BiFeO3‐based lead‐free ceramics, ferroelectric polarization is suppressed by a polishing‐induced surface damage layer through the inhibition of Bi3⁺ off‐centering and nanoscale domain formation. Upon thermal annealing, the damaged layer is relaxed, Bi3⁺ displacement is restored, and nanoscale domains are reactivated, resulting in the recovery of the
Sangwook Kim, Hyunwook Nam, Hae In Choi
wiley +1 more source
Physical descriptions of the bacterial nucleoid at large scales, and their biological implications. [PDF]
, 2012 Recent experimental and theoretical approaches have attempted to quantify the physical organization (compaction and geometry) of the bacterial chromosome with its complement of proteins (the nucleoid).
Bassetti, B. +7 more
core +3 more sources