Results 131 to 140 of about 4,884 (228)
The study of dynamic characteristics during the vibration processing of parts
MATEC Web of Conferences, 2018 The results of theoretical studies on the dynamic characteristics of the process of vibroprocessing are presented, the essence of which is to create conservative zones limited by the current lines of a certain fixed vector field, which contributes to the
Levchenko Elena
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mBio, 2019 Division ring formation at midcell is controlled by various mechanisms in Escherichia coli, one of them being the linkage between the chromosomal Ter macrodomain and the Z-ring mediated by MatP, a DNA binding protein that organizes this macrodomain and ...
Begoña Monterroso +9 more
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READDI protocol: Crystallisation of CHIKV nsP3 macrodomain v1
Chikungunya virus (CHIKV) causes severe fever, rash and debilitating joint pain that can last for months or even years. Millions of people have been infected with CHIKV, mostly in low- and middle-income countries, and the virus continues to spread into new areas due to the geographical expansion of its mosquito hosts.
Jasmin Aschenbrenner +4 more
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Proximal ADP-ribose Hydrolysis in Trypanosomatids is Catalyzed by a Macrodomain
Scientific Reports, 2016 AbstractADP-ribosylation is a ubiquitous protein modification utilized by both prokaryotes and eukaryotes for several cellular functions, such as DNA repair, proliferation and cell signaling. Higher eukaryotes, such as humans, utilize various enzymes to reverse the modification and to regulate ADP-ribose dependent signaling.
Lehtiö Lari, Haikarainen Teemu Johannes
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PARP14 and PARP9/DTX3L regulate interferon-induced ADP-ribosylation
The EMBO JournalPARP-catalysed ADP-ribosylation (ADPr) is important in regulating various cellular pathways. Until recently, PARP-dependent mono-ADP-ribosylation has been poorly understood due to the lack of sensitive detection methods.
Pulak Kar +18 more
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The MacroH2A1.1 – PARP1 Axis at the Intersection Between Stress Response and Metabolism
Frontiers in Genetics, 2018 The exchange of replication-coupled canonical histones by histone variants endows chromatin with specific features. The replacement of the canonical H2A histone for the histone variant macroH2A is one of the most remarkable epigenetic modifications.
Sarah Hurtado-Bagès +5 more
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In silico studies of phycobilins as potential candidates for inhibitors of viral proteins associated with COVID-19 [PDF]
Journal of the Serbian Chemical SocietyIn this in silico study, it was investigated whether phycobilins (phycocyanobilin, phycoerythrobilin and phycourobilin) could be inhibitors of the activity of the main proteins of the SARS-CoV-2 virus. All chromophores exhibited a binding energy value of
Jovanović Vesna B. +2 more
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Observation of Macrodomain Structures by Laser Scanning Confocal Microscopy.
KOBUNSHI RONBUNSHU, 1996 マクロ相分離したポリスチレン-ポリイソプレンジブロックコポリマー/ホモポリスチレンブレンド (重量比5/95) の三次元構造を, 共焦点レーザー顕微鏡を用いて観察した. また超薄切片の透過型電子顕微鏡観察も合わせて行った. ブロックコポリマーが形成するミクロドメイン界面からの反射を利用してブロックコポリマーリッチなマクロドメインを観察し, 得られた共焦点レーザー顕微鏡データより構造のさまざまな断面像を再構築することにより, その3次元形態およびその内部構造を明らかにすることができた.
Eiji NAKAMURA +2 more
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Poly(ADP-Ribosyl)ation affects stabilization of CHE-1 protein in response to DNA damage [PDF]
, 2011 Post-translation modifications play a crucial role in coordinating the cellular response to DNA damage. Double strand DNA breaks (DSBs) trigger the activation of ATM and Chk2 kinases, which represent the primary transducers in the signalling cascade ...
BACALINI, MARIA GIULIA
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CHD1L: a new candidate gene for congenital anomalies of the kidneys and urinary tract (CAKUT) [PDF]
, 2017 Background. Recently, we identified a microduplication in chromosomal band 1q21.1 encompassing the CHD1L/ALC1 gene encoding a chromatin-remodelling enzyme in congenital anomalies of the kidneys and urinary tract (CAKUT) patient. Methods.
Brockschmidt, Antje +14 more
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