Results 121 to 130 of about 4,884 (228)

Reentrant Phenomenon in Barium Titanate Zirconate‐Based Relaxor Ferroelectrics

open access: yesSmall, Volume 21, Issue 35, September 4, 2025.
This study explores reentrant relaxor behavior in (1 − x)Ba(Ti0.85Zr0.15)O3‐xBi(Zn2/3Nb1/3)O3 (BTZr‐BZNb). Substituting with BZNb disrupts long‐range polar order, creating nanometer‐scale “antipolar clusters” within a polar matrix. The competition between polar modes and antiferrodistortive rotations leads to low‐temperature relaxor anomalies ...
Eva Kröll   +5 more
wiley   +1 more source

PARP14 is an interferon-induced host factor that promotes IFN production and affects the replication of multiple viruses

open access: yesmBio
PARP14 is a 203 kDa multi-domain protein that is primarily known as an ADP-ribosyltransferase and is involved in a variety of cellular functions, including DNA damage, microglial activation, inflammation, and cancer progression.
Srivatsan Parthasarathy   +16 more
doaj   +1 more source

Re‐evaluation of PTEN as an ADP‐ribosylated tankyrase binding partner

open access: yesThe FEBS Journal, Volume 292, Issue 17, Page 4611-4630, September 2025.
We reveal that PTEN and its conserved putative tankyrase‐binding motif (pTBM) originated before tankyrases in evolution. We demonstrate that the pTBM shows no binding to tankyrase ARC domains, but it has structural and functional roles. We show, using recombinant proteins, that PTEN is not a tankyrase binding partner and substrate, and that catalytic ...
Chiara Bosetti   +5 more
wiley   +1 more source

Achievement of high energy density and efficiency in Bi(Mg0.5Hf0.5)O3 modified Ba0.55Sr0.45TiO3 ceramics

open access: yesInternational Journal of Applied Ceramic Technology, Volume 22, Issue 5, September/October 2025.
BMH introduction in BST lattice disrupted the long range ferroelectric domains transforming it to polar nano regions (PNRs) that lead to increased bandgap and hence increaed the dielectric breakdown field with slimer P‐E loop. Abstract (1 ‒ x)Ba0.55Sr0.45TiO3‒xBi(Mg0.5Hf0.5)O3 [(1 ‒ x)BST‒xBMH] (x = 0, 0.05, 0.10, 0.15, and 0.20) ceramics were ...
Ihsan Ullah   +7 more
wiley   +1 more source

Poly(ADP-ribose) Polymerase-1 (PARP1) in Atherosclerosis: From Molecular Mechanisms to Therapeutic Potential [PDF]

open access: yes, 2014
Poly(ADP-ribosyl)ation reactions, carried out by poly(ADP-ribose) polymerases (PARPs/ARTDs), are reversible posttranslational modifications impacting on numerous cellular processes (e.g., DNA repair, transcription, metabolism, or immune functions). PARP1
Bay, Péter, Little, P., Liu, P., Xu, S.
core   +1 more source

Large High‐Temperature Piezoelectric Response of Lead‐free BiFeO3–BaTiO3 Originating from Relaxor Disorder

open access: yesSmall, Volume 21, Issue 31, August 7, 2025.
In situ, temperature‐dependent analysis of the piezoelectric response of the 0.67BFO‐0.33BTO system reveals an exceptionally high piezoelectric response of ≈1200 pm V−1. Detailed temperature‐dependent examination uncovers three distinct stages, mutually contributing to the overall response.
Antonio Iacomini   +6 more
wiley   +1 more source

Synthesis of Amphiphilic Naphthalenediimides and Investigation of their Bioimaging Potential in Large Unilamellar Vesicles

open access: yesEuropean Journal of Organic Chemistry, Volume 28, Issue 28, July 29, 2025.
The efficient synthesis of a small library of nonsymmetrical panchromatic naphthalenediimides is reported. The electron‐donating groups on the aromatic core are varied to tune the fluorophores' photophysical properties . The ability of the dyes to partition and light up inside the lipid bilayer membrane in liposomal models is investigated to evaluate ...
Francesca Cardano   +5 more
wiley   +1 more source

Acid Sphingomyelinase Promotes Endothelial Stress Response in Systemic Inflammation and Sepsis

open access: yesMolecular Medicine, 2016
The pathophysiology of sepsis involves activation of acid sphingomyelinase (SMPD1) with subsequent generation of the bioactive mediator ceramide. We herein evaluate the hypothesis that the enzyme exerts biological effects in endothelial stress response ...
Ha-Yeun Chung   +9 more
doaj   +1 more source

Functions of Alphavirus Macrodomain-containing protein nsP3 [PDF]

open access: yes, 2011
Alphaviruses are positive strand RNA viruses that replicate in association with cellular membranes. The viral RNA replication complex consists of four non-structural proteins nsP1-nsP4 which are essential for viral replication.
Neuvonen, Maarit
core  

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