Results 181 to 190 of about 29,619 (221)
Some of the next articles are maybe not open access.
Related searches:
Related searches:
MAIT Cells in Health and Disease
Annual Review of Immunology, 2020Mucosal-associated invariant T (MAIT) cells have been attracting increasing attention over the last few years as a potent unconventional T cell subset. Three factors largely account for this emerging interest. Firstly, these cells are abundant in humans, both in circulation and especially in some tissues such as the liver.
Nicholas M Provine, Paul Klenerman
exaly +3 more sources
Immunology and Cell Biology, 2018 AbstractMucosal associated invariant T cells (MAIT cells) bear a T cell receptor (TCR) that specifically targets microbially derived metabolites. Functionally, they respond to bacteria and yeasts, which possess the riboflavin pathway, essential for production of such metabolites and which are presented on MR1.
James E Ussher +2 more
exaly +3 more sources
MAIT cells in infectious diseases
Current Opinion in Immunology, 2017In humans, MAIT cells represent the most abundant T cell subset reacting against bacteria. Their frequency in the blood is decreased in a large variety of infectious diseases of either bacterial or viral origin. MAIT cells accumulate at the site of bacterial infection and are protective in experimental infection models.
Marion, Salou +2 more
openaire +2 more sources
2007
In this chapter, we propose a multi-agent-based information technology (IT) security approach (MAITS) as a holistic solution to the increasing needs of securing computer systems. Each specialist task for security requirements is modeled as a specialist agent.
openaire +1 more source
In this chapter, we propose a multi-agent-based information technology (IT) security approach (MAITS) as a holistic solution to the increasing needs of securing computer systems. Each specialist task for security requirements is modeled as a specialist agent.
openaire +1 more source
MAIT cells as attractive vaccine targets
FEBS Letters, 2019Mucosal‐associated invariant T (MAIT) cells are a subset of T cells that perform innate‐like immunity functions upon recognition of small molecule vitamin B metabolites presented by the MHC, class I‐related protein‐1 (MR1). MAIT cells are profuse in humans, but especially abundant in blood, liver, lungs, and mucosal layers.
A. Michael Downey +2 more
openaire +3 more sources
MAIT cell subtypes in multiple sclerosis
Journal of Neuroimmunology, 2020In patients with multiple sclerosis (MS) and healthy controls (HC) we studied circulating MAIT cells and MAIT cell subtypes expressing CXCR3 and CCR6 by flow cytometry. Absolute numbers of MAIT cells and specifically Tc17-like MAIT cells were lower in patients with primary progressive MS (PPMS) than in controls. Low numbers of Tc17-like MAIT cells were
Ammitzbøll, Cecilie +5 more
openaire +3 more sources
MAITs, MR1 and vitamin B metabolites
Current Opinion in Immunology, 2014αβT-cell mediated immunity is traditionally characterised by recognition of peptides or lipids presented by the major histocompatibility complex (MHC) or the CD1 family respectively. Recently the antigenic repertoire of αβT-cells has been expanded with the observation that mucosal-associated invariant T-cells (MAIT cells), an abundant population of ...
Richard W, Birkinshaw +4 more
openaire +2 more sources
Nature Reviews Immunology, 2019
Commensal bacteria at mucosal surfaces can remotely control the thymic maturation of mucosal-associated invariant T cells through the production of microbial factors that enter the circulation and are taken up by thymic cells.
openaire +2 more sources
Commensal bacteria at mucosal surfaces can remotely control the thymic maturation of mucosal-associated invariant T cells through the production of microbial factors that enter the circulation and are taken up by thymic cells.
openaire +2 more sources
MAIT cells and pathogen defense
Cellular and Molecular Life Sciences, 2014Mucosa-associated invariant T (MAIT) cells are a unique population of innate T cells that are abundant in humans. These cells possess an evolutionarily conserved invariant T cell receptor α chain restricted by the nonpolymorphic class Ib major histocompatibility (MHC) molecule, MHC class I-related protein (MR1). The recent discovery that MAIT cells are
openaire +2 more sources