Results 181 to 190 of about 10,390 (221)
The Role of Innate T Cells in Inflammatory Disorders in Asthma and Chronic Rhinosinusitis. [PDF]
Clin Exp OtorhinolaryngolLee MS, Kim DW, Lee YJ.
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The antigen-presenting molecule MR1 binds host-generated riboflavin catabolites. [PDF]
J Exp MedAbdelaal MR +10 more
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Editorial: Epigenetic regulation of T cell function in type 1 diabetes. [PDF]
Front ImmunolKalim UU, Grieco GE.
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Role of MAIT cells in metabolic diseases
Molecular Immunology, 2021MAIT cells are innate-like T cells that are enriched in mucosal sites and tissues including adipose tissue and liver. They play an important role in immunity against microbial pathogens. Recently, it has been reported that MAIT cells could also be important in metabolic diseases and can be involved in setting up and maintaining chronic inflammation. In
Amine, Toubal, Agnès, Lehuen
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MAIT cells in infectious diseases
Current Opinion in Immunology, 2017In humans, MAIT cells represent the most abundant T cell subset reacting against bacteria. Their frequency in the blood is decreased in a large variety of infectious diseases of either bacterial or viral origin. MAIT cells accumulate at the site of bacterial infection and are protective in experimental infection models.
Marion, Salou +2 more
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2007
In this chapter, we propose a multi-agent-based information technology (IT) security approach (MAITS) as a holistic solution to the increasing needs of securing computer systems. Each specialist task for security requirements is modeled as a specialist agent.
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In this chapter, we propose a multi-agent-based information technology (IT) security approach (MAITS) as a holistic solution to the increasing needs of securing computer systems. Each specialist task for security requirements is modeled as a specialist agent.
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MAIT cell development in mice and humans
Molecular Immunology, 2021MAIT cells arise in the thymus following rearrangement of a T cell receptor (TCR) reactive against microbial vitamin B2-derived metabolites presented by the MHC-Ib molecule, MR1. Mechanisms that are conserved in mammals ensure the frequent production of MR1-restricted TCRs and the intra-thymic differentiation of MR1-restricted thymocytes into effector ...
Marion, Salou +2 more
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MAIT cells and pathogen defense
Cellular and Molecular Life Sciences, 2014Mucosa-associated invariant T (MAIT) cells are a unique population of innate T cells that are abundant in humans. These cells possess an evolutionarily conserved invariant T cell receptor α chain restricted by the nonpolymorphic class Ib major histocompatibility (MHC) molecule, MHC class I-related protein (MR1). The recent discovery that MAIT cells are
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Nature Reviews Immunology, 2019
Commensal bacteria at mucosal surfaces can remotely control the thymic maturation of mucosal-associated invariant T cells through the production of microbial factors that enter the circulation and are taken up by thymic cells.
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Commensal bacteria at mucosal surfaces can remotely control the thymic maturation of mucosal-associated invariant T cells through the production of microbial factors that enter the circulation and are taken up by thymic cells.
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