Results 71 to 80 of about 19,848 (176)
A Perspective of Soy Isoflavones on Analytical, Biological, and Chemical Attributes
Legume Science, Volume 8, Issue 3, September 2026.ABSTRACT This review covers key aspects of soybean (Glycine max), with a particular focus on its isoflavone content and biological properties. Soybeans maintain their position as both a nutraceutical and a pharmaceutical crop, with a broad range of dietary items used worldwide, including soy milk, fermented soy products, and various dietary supplements.
Sristy Suman +4 more
wiley +1 more source
Dietary α-linolenic acid reduces COX-2 expression and induces apoptosis of hepatoma cells
Journal of Lipid Research, 2004 Fatty acid synthetase (FAS) is overexpressed in various tumor tissues, and its inhibition and/or malonyl-CoA accumulation have been correlated to apoptosis of tumor cells.
A. Vecchini +11 more
doaj +1 more source
Prevention of Myc‐Driven Prostate Cancer in Mice by Oral Administration of Sulforaphane
Molecular Carcinogenesis, Volume 65, Issue 9, Page 1052-1062, September 2026.ABSTRACT Prevention is desirable to reduce suffering and death from prostate cancer. However, a clinical‐grade intervention for the prevention of this malignancy is still lacking. This study was undertaken to determine the feasibility of prostate cancer prevention by broccoli constituent sulforaphane (SFN) because epidemiological studies have suggested
Krishna B. Singh +3 more
wiley +1 more source
The Journal of Pathology, Volume 270, Issue 1, Page 98-113, September 2026.Abstract Acquired lipodystrophy in the dermal white adipose tissue (DWAT) is an early phenotype of skin fibrosis, followed by the accumulation of extracellular matrix (ECM). Lipodystrophy syndromes are estimated to affect 1 in 20,000 people and are associated with metabolic comorbidities.
Suneeti R Madhavan +10 more
wiley +1 more source
Phytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.Obesity and hypertension co‐exist and share molecular mechanisms in terms of dietary therapy, modulated by food bioactive constituents. ABSTRACT Obesity and hypertension are among the most pressing global public health challenges. They frequently co‐exist, with obesity‐related hypertension accounting for an estimated 75% of the hypertension burden ...
Samuel Oluwasegun Maccarthy +3 more
wiley +1 more source
Environmental Toxicology, Volume 41, Issue 9, Page 709-729, September 2026.ABSTRACT Prostate cancer (PCa) is an endocrine‐related cancer highly dependent on androgenic signaling. Beyond hormone dependence, extrinsic factors play a significant role in the risk of developing PCa, which raises concern about the influence of environmental compounds such as endocrine‐disrupting chemicals (EDCs). Tributyltin (TBT) is an EDC used in
Mariana Feijó +9 more
wiley +1 more source
Autophagy in MASLD: A Metabolic and Precision Medicine Perspective
Liver International, Volume 46, Issue 9, September 2026.ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common chronic liver condition worldwide and a major contributor to cirrhosis and hepatocellular carcinoma (HCC). While metabolic triggers such as obesity and insulin resistance are key drivers of MASLD, growing evidence has identified defects in intracellular quality
Alessandra Cazzaniga +4 more
wiley +1 more source
New Phytologist, Volume 251, Issue 6, Page 3507-3521, September 2026.Synthetic community complexity reduction designs. Summary Plant growth is influenced by the composition of its associated microbiome. The inherent complexity and functional redundancy of natural plant microbiomes present a formidable barrier to understanding the myriad biological interactions therein.
Dean Pettinga +8 more
wiley +1 more source
Nature Communications, 2016 Polyketides are typically assembled from a starter unit and malonyl- and/or methylmalonyl-CoA-derived extender units, but the macrolide antibiotics stambomycins incorporate non-standard alkylmalonyl-CoA extender units.
Lauren Ray +9 more
doaj +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, Volume 16, Issue 8, Page 1537-1549, August 2026.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source