Results 141 to 150 of about 12,732 (162)

Flunarizine as a Candidate for Drug Repurposing Against Human Pathogenic Mammarenaviruses. [PDF]

Viruses
Ofodile CA, Uzochukwu IC, Ezebuo FC, Ejiofor I, Adebola M, Okpoli I, Cubitt B, Witwit H, Okwuanaso CB, Onyemelukwe N, de la Torre JC.   +10 more
europepmc   +1 more source

Lassa virus circumvents macrophage and dendritic cell antiviral defences in its natural reservoir, the Natal multimammate mouse (Mastomys natalensis). [PDF]

Npj Viruses
Corrales N, Wozniak DM, Yordanova IA, Suder EL, Morales AE, Lander A, Hansen-Kant K, Hiller M, Prescott JB.   +8 more
europepmc   +1 more source

A STAT1-Knockout Mouse Model for Chapare Virus Infection and Pathogenesis. [PDF]

Viruses
Monticelli SR, Kuehne AI, Batchelor TG, Richardson JB, Lapoint Z, Williams JL, Coyne SR, Raymond JLW, Zeng X, Stefan CP, Koehler JW, Kugelman JR, Herbert AS.   +12 more
europepmc   +1 more source

U-73122, a phospholipase C inhibitor, impairs lymphocytic choriomeningitis virus virion infectivity. [PDF]

J Gen Virol
Mizuma K, Hashizume M, Urata S, Shindo K, Takashima A, Mizuta S, Iwasaki M.   +6 more
europepmc   +1 more source

Characterization of bi-segmented and tri-segmented recombinant Pichinde virus particles. [PDF]

J Virol
Murphy H, Huang Q, Jensen J, Weber N, Mendonça L, Ly H, Liang Y.   +6 more
europepmc   +1 more source

Türkiye’de saptanan ilk Mammarenavirus soyu

, 2019
Erdin, Mert, MATUR, FERHAT, Çoğal, Muhsin, SÖZEN, MUSTAFA, Kalkan, Kürşat Kenan, ÇOLAK, FARUK, ÖKTEM, İBRAHİM MEHMET ALİ, ÇETİNTAŞ, ORTAÇ, POLAT, CEYLAN   +8 more
core  

Complete Genome Sequence of a Novel Variant of Wenzhou Mammarenavirus [PDF]

Genome Announcements, 2017
ABSTRACT Wenzhou mammarenavirus (WENV) is a novel species of Arenavirus that was first detected in China. We report here a novel WENV variant (WENV G107) from liver samples of Rattus norvegicus that shares 84.7% to 86.8% (large [L] segment) and 84.2% to 87.8% (small [S] segment ...
Zhaojun Duan
exaly   +4 more sources

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Pseudotyped Viruses for Mammarenavirus

Advances in Experimental Medicine and Biology, 2023
Mammarenaviruses are classified into New World arenaviruses (NW) and Old World arenaviruses (OW). The OW arenaviruses include the first discovered mammarenavirus-lymphocytic choriomeningitis virus (LCMV) and the highly lethal Lassa virus (LASV). Mammarenaviruses are transmitted to human by rodents, resulting in severe acute infections and hemorrhagic ...
Youchun Wang, Wang Youchun
exaly   +3 more sources

Molecular Engineering of a Mammarenavirus with Unbreachable Attenuation

Journal of Virology, 2023
Several mammarenaviruses cause severe disease in humans and pose important public health problems in their regions of endemicity. Currently, no FDA-licensed mammarenavirus vaccines are available, and anti-mammarenaviral therapy is limited to an off-label use of ribavirin whose efficacy is controversial.
Saori Sakabe, Beatrice Cubitt, Luis Martinez-Sobrido   +2 more
exaly   +3 more sources

Development of Reverse Genetics for the Prototype New World Mammarenavirus Tacaribe Virus

Journal of Virology, 2020
To date, no Food and Drug Administration (FDA)-approved vaccines are available to combat hemorrhagic fever caused by mammarenavirus infections in humans. Treatment of mammarenavirus infections is limited to the off-label use of ribavirin, which is partially effective and associated with significant side effects.
Chengjin Ye, Juan CARLOS De La Torre, Luis Martinez-Sobrido   +2 more
exaly   +4 more sources