Diagnostic value of monocyte chemoattractant Protein-1, soluble mannose receptor, Presepsin, and Procalcitonin in critically ill children admitted with suspected sepsis [PDF]
BMC Pediatrics, 2021 Introduction The differentiation between systemic inflammatory response syndrome and sepsis is very important as it determines essential treatment decisions, such as selection, initiation, and duration of antibiotic therapy.
Noha A. Hassuna +7 more
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Cooperative stimulation of dendritic cells by Cryptococcus neoformans mannoproteins and CpG oligodeoxynucleotides. [PDF]
PLoS ONE, 2008 While mannosylation targets antigens to mannose receptors on dendritic cells (DC), the resultant immune response is suboptimal. We hypothesized that the addition of toll-like receptor (TLR) ligands would enhance the DC response to mannosylated antigens ...
Jennifer M Dan +3 more
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The Mannose Receptor: From Endocytic Receptor and Biomarker to Regulator of (Meta)Inflammation [PDF]
Frontiers in Immunology, 2021 The mannose receptor is a member of the C-type lectin (CLEC) family, which can bind and internalize a variety of endogenous and pathogen-associated ligands.
Hendrik J. P. van der Zande +4 more
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Detoxified pneumolysin derivative ΔA146Ply inhibits triple- negative breast cancer metastasis mainly via mannose receptor-mediated autophagy inhibition [PDF]
VirulenceThe detoxified pneumolysin derivative ΔA146Ply has been proven to have a direct anti-triple negative breast cancer effect by our group, but its work model remains unclear.
Hong Zhang +6 more
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Chronic mucocutaneous candidiasis associated with paracoccidioidomycosis in a patient with mannose receptor deficiency: First case reported in the literature [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 2021 We describe the first report of a patient with chronic mucocutaneous candidiasis associated with disseminated and recurrent paracoccidioidomycosis. The investigation demonstrated that the patient had a mannose receptor deficiency, which would explain the
Dewton de Moraes Vasconcelos +2 more
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Decoding the mannose receptor-mAb interaction: the importance of high-mannose N-glycans and glycan-pairing [PDF]
mAbsDuring the development process of therapeutic monoclonal antibodies (mAbs), it is crucial to control (critical) quality attributes such as N-glycosylation influencing pharmacokinetics (PK) and Fc effector functions.
Julia Baumeister +7 more
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Mannose receptor is an HIV restriction factor counteracted by Vpr in macrophages [PDF]
eLife, 2020 HIV-1 Vpr is necessary for maximal HIV infection and spread in macrophages. Evolutionary conservation of Vpr suggests an important yet poorly understood role for macrophages in HIV pathogenesis.
Jay Lubow +11 more
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Mannose Receptor Mediates the Activation of Chitooligosaccharides on Blunt Snout Bream (Megalobrama amblycephala) Macrophages. [PDF]
Front Immunol, 2021 Ouyang A, Wang H, Su J, Liu X.
europepmc +3 more sources
Mannose Receptor-Mediated Carbon Nanotubes as an Antigen Delivery System to Enhance Immune Response Both In Vitro and In Vivo. [PDF]
Int J Mol Sci, 2022 Feng H +10 more
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Targeted macrophage mannose receptor (CD206)-specific protein delivery via engineered extracellular vesicles. [PDF]
HeliyonOvchinnikova LA +6 more
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