Results 1 to 10 of about 331,204 (356)
Journal of Orofacial Sciences, 2010 Matrix metalloproteinases (MMPs), also known as matrixins, belong to a group of zinc-dependent proteins, which are thought to play a central role in the breakdown of extracellular matrix. Collagen, elastin, gelatin and casein are major components cleaved by MMPs.
S Sahitya +2 more
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Matrix Metalloproteinases and Glaucoma
Biomolecules, 2022 Matrix metalloproteinases (MMPs) are enzymes that decompose extracellular matrix (ECM) proteins. MMPs are thought to play important roles in cellular processes, such as cell proliferation, differentiation, angiogenesis, migration, apoptosis, and host ...
Moo Hyun Kim, Su-Ho Lim
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Analysis of inflammatory biomarkers IL-6, vascular endothelial growth factor and matrix metalloproteinases-9 expression in endometriosis [PDF]
SAGE Open MedicineObjective: Special attention has been paid to genetic mechanisms that might have a significant impact on the context of the risk of developing endometriosis, in recent years.
Maofang Hua +6 more
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Journal of UOEH, 1997 Matrix-degrading enzymes, matrix metalloproteinases, are members of a unique family of Zinc-binding endopeptidases that are responsible for the metabolism of extracellular components in the tissue stroma. Their controlled expression is essential for normal processes such as wound healing and tissue remodeling, including embryogenesis.
Susan A. Watson +4 more
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Direct electrochemical reduction of graphene oxide thin film for aptamer-based selective and highly sensitive detection of Matrix metalloproteinase 2 [PDF]
Talanta, V. 274, 1 July 2024, 126079, 2023 Simple and low-cost biosensing solutions are suitable for point-of-care applications aiming to overcome the gap between scientific concepts and technological production. To compete with sensitivity and selectivity of golden standards, such as liquid chromatography, the functionalization of biosensors is continuously optimized to enhance the signal and ...
arxiv +1 more source
Biomedicines, 2021 Collagen cleavage by matrix metalloproteinase (MMP) is considered a major cause of dental resins long term failure. Most MMP inhibitors display significant toxicity and are unsuitable for dental resins’ applications. Here we report a study of a new class
Helena Laronha +8 more
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Matrix metalloproteinases-9 and tissue inhibitor of matrix metalloproteinases-1 in sarcoidosis patients [PDF]
Arhiv za farmaciju, 2017 Matrix metaloproteinases (MMPs) and their specific inhibitors - tissue inhibitors of matrix metalloproteinases (TIMPs) play an important role in pulmonary extracellular matrix destruction. Sarcoidosis is an inflammatory disease affecting multiple organs.
Ivanišević Jasmina +6 more
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Extracellular Matrix Enzymes and Immune Cell Biology
Frontiers in Molecular Biosciences, 2021 Remodelling of the extracellular matrix (ECM) by ECM metalloproteinases is increasingly being associated with regulation of immune cell function. ECM metalloproteinases, including Matrix Metalloproteinases (MMPs), A Disintegrin and Metalloproteinases ...
Meagan McMahon +4 more
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Matrix Metalloproteinases in Predicting Nonproliferative Diabetic Retinopathy in Old Age
Oftalʹmologiâ, 2023 The development of diabetic retinopathy is associated with matrix metalloproteinases, but they are rarely used to predict this pathology. The purpose of the study is to predict the development of nonproliferative diabetic retinopathy in old age based on ...
O. L. Fabikantov +3 more
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Challenges in Matrix Metalloproteinases Inhibition
Biomolecules, 2020 Matrix metalloproteinases are enzymes that degrade the extracellular matrix. They have different substrates but similar structural organization. Matrix metalloproteinases are involved in many physiological and pathological processes and there is a need ...
Helena Laronha +7 more
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