Results 1 to 10 of about 142,106 (266)

Matrix Metalloproteinases and Glaucoma

open access: yesBiomolecules, 2022
Matrix metalloproteinases (MMPs) are enzymes that decompose extracellular matrix (ECM) proteins. MMPs are thought to play important roles in cellular processes, such as cell proliferation, differentiation, angiogenesis, migration, apoptosis, and host ...
Moo Hyun Kim, Su-Ho Lim
doaj   +1 more source

Polymerizable Matrix Metalloproteinases’ Inhibitors with Potential Application for Dental Restorations

open access: yesBiomedicines, 2021
Collagen cleavage by matrix metalloproteinase (MMP) is considered a major cause of dental resins long term failure. Most MMP inhibitors display significant toxicity and are unsuitable for dental resins’ applications. Here we report a study of a new class
Helena Laronha   +8 more
doaj   +1 more source

Matrix metalloproteinases-9 and tissue inhibitor of matrix metalloproteinases-1 in sarcoidosis patients [PDF]

open access: yesArhiv za farmaciju, 2017
Matrix metaloproteinases (MMPs) and their specific inhibitors - tissue inhibitors of matrix metalloproteinases (TIMPs) play an important role in pulmonary extracellular matrix destruction. Sarcoidosis is an inflammatory disease affecting multiple organs.
Ivanišević Jasmina   +6 more
doaj   +1 more source

Extracellular Matrix Enzymes and Immune Cell Biology

open access: yesFrontiers in Molecular Biosciences, 2021
Remodelling of the extracellular matrix (ECM) by ECM metalloproteinases is increasingly being associated with regulation of immune cell function. ECM metalloproteinases, including Matrix Metalloproteinases (MMPs), A Disintegrin and Metalloproteinases ...
Meagan McMahon   +4 more
doaj   +1 more source

Matrix Metalloproteinases in Predicting Nonproliferative Diabetic Retinopathy in Old Age

open access: yesOftalʹmologiâ, 2023
The development of diabetic retinopathy is associated with matrix metalloproteinases, but they are rarely used to predict this pathology. The purpose of the study is to predict the development of nonproliferative diabetic retinopathy in old age based on ...
O. L. Fabikantov   +3 more
doaj   +1 more source

Challenges in Matrix Metalloproteinases Inhibition

open access: yesBiomolecules, 2020
Matrix metalloproteinases are enzymes that degrade the extracellular matrix. They have different substrates but similar structural organization. Matrix metalloproteinases are involved in many physiological and pathological processes and there is a need ...
Helena Laronha   +7 more
doaj   +1 more source

The relationship between the first episode of wheezing and matrix metalloproteinases-9 and MMP-2 and tissue inhibitors of MMP-1 levels in preterm infants

open access: yesAnnals of Thoracic Medicine, 2013
Aims: Matrix metalloproteinases (MMP) have been associated with neonatal lung morbidity and MMP dysregulation contributes to the pathology of chronic and acute lung disorders.
Rabia Gonul Sezer   +5 more
doaj   +1 more source

Osteoarticular complications of brucellosis: The diagnostic value and importance of detection matrix metalloproteinases [PDF]

open access: yesActa Medica Academica, 2015
Objectives. Matrix metalloproteinases (MMPs) has been implicated in the pathogenesis of infective, cancer and autoimmune diseases. In this study, we investigated the serum level of MMPs and its clinical importance in human brucellosis.
Maida Šiširak, Mirsada Hukić
doaj   +1 more source

MT4-MMP deficiency increases patrolling monocyte recruitment to early lesions and accelerates atherosclerosis

open access: yesNature Communications, 2018
Matrix metalloproteinases (MMP) are involved in vascular remodeling associated with plaque progression. Little is known about their immune regulatory role in vascular disorders.
Cristina Clemente   +14 more
doaj   +1 more source

Role of matrix Metalloproteinases in pituitary adenoma invasion

open access: yesChinese Neurosurgical Journal, 2018
Though pituitary adenomas are benign tumors in most cases, a considerable fraction of PAs behave in a malignant-like manner and invade to the adjacent structures in sellar region, especially the cavernous sinuses.
Chengxian Yang, Xinjie Bao, Renzhi Wang
doaj   +1 more source

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