Results 11 to 20 of about 156,207 (304)
Biological role of matrix stiffness in tumor growth and treatment
Journal of Translational Medicine, 2022 In recent years, the biological role of changes in physical factors in carcinogenesis and progression has attracted increasing attention. Matrix stiffness, also known as ECM stress, is a critical physical factor of tumor microenvironment and remains ...
Boer Deng +5 more
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Targeting extracellular matrix stiffness for cancer therapy [PDF]
Frontiers in ImmunologyThe physical characteristics of the tumor microenvironment (TME) include solid stress, interstitial fluid pressure, tissue stiffness and microarchitecture.
Xiuqin Feng +6 more
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Analytical Stiffness Matrix for Curved Metal Wires [PDF]
Procedia Structural Integrity, 2018 The paper presents an analytic stiffness matrix for curved thin metal wires, derived by the application of the second Castigliano’s Theorem. The matrix accounts both bending and axial stiffness contributions in plane.
Marotta, E +5 more
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Influence of the Order Exchange of the Node Connection in the Force Analysis of Steel Structures
Frontiers in Materials, 2022 In the mechanical analysis of steel structures, whether it is static analysis or dynamic analysis, it is necessary to establish the structural stiffness matrix first.
Shuai Luo +4 more
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Stiffness of Woven Ceramic Matrix Composites with Matrix Cracks
40th Structures, Structural Dynamics, and Materials Conference and Exhibit, 1999 An account is given of an ongoing study aimed at the analysis of plain weave ceramic matrix woven composites (CMC) with matrix cracks. The issues important for the analysis of such composites and for a development of an analytical model of thermography ...
Larry Byrd +3 more
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Matrix stiffness, endothelial dysfunction and atherosclerosis
Molecular Biology Reports, 2022 Abstract Background Atherosclerosis (AS) is the leading cause of the human cardiovascular disease (CVDs). Endothelial dysfunction promotes the monocytes infiltration and inflammation that participate fundamentally in atherogenesis. Endothelial cells (EC) have been recognized as mechanosensitive cells and have different responses to distinct ...
Zichen Xu +7 more
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Nonswelling and Hydrolytically Stable Hydrogels Uncover Cellular Mechanosensing in 3D
Advanced Science, 2022 While matrix stiffness regulates cell behavior on 2D substrates, recent studies using synthetic hydrogels have suggested that in 3D environments, cell behavior is primarily impacted by matrix degradability, independent of stiffness.
Hongyan Long +4 more
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Bioactive Materials, 2021 In the three-dimensional (3D) tumor microenvironment, matrix stiffness is associated with the regulation of tumor cells behaviors. In vitro tumor models with appropriate matrix stiffness are urgently desired.
Yonggang Lv +3 more
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Nanomaterials, 2022 The typically-used element torsional stiffness GJ/L (where G is the shear modulus, J the St. Venant torsion constant, and L the element length) may severely underestimate the torsional stiffness of thin-walled nanostructural members, due to neglecting ...
Wen-Hao Pan +3 more
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Stiffness analysis of a 3-DOF parallel mechanism for engineering special machining [PDF]
Mechanical Sciences, 2022 There are considerably rigorous requirements for accuracy and stability of the mechanism to accomplish large-scale and complex surface machining tasks in the aerospace field.
H. Zhang +7 more
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