Results 11 to 20 of about 1,985,960 (297)
Stiffness in human joints [PDF]
, 1993 Articular stiffness is an important symptom in most arthritic diseases and appears to be a useful marker of disease activity in rheumatoid arthritis.
Helliwell, Philip Stephen
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Matrix stiffness, endothelial dysfunction and atherosclerosis
Molecular Biology Reports, 2022 Abstract Background Atherosclerosis (AS) is the leading cause of the human cardiovascular disease (CVDs). Endothelial dysfunction promotes the monocytes infiltration and inflammation that participate fundamentally in atherogenesis. Endothelial cells (EC) have been recognized as mechanosensitive cells and have different responses to distinct ...
Zichen Xu +7 more
openaire +2 more sources
Nonswelling and Hydrolytically Stable Hydrogels Uncover Cellular Mechanosensing in 3D
Advanced Science, 2022 While matrix stiffness regulates cell behavior on 2D substrates, recent studies using synthetic hydrogels have suggested that in 3D environments, cell behavior is primarily impacted by matrix degradability, independent of stiffness.
Hongyan Long +4 more
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Targeting extracellular matrix stiffness for cancer therapy
Frontiers in ImmunologyThe physical characteristics of the tumor microenvironment (TME) include solid stress, interstitial fluid pressure, tissue stiffness and microarchitecture.
Xiuqin Feng +6 more
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Bioactive Materials, 2021 In the three-dimensional (3D) tumor microenvironment, matrix stiffness is associated with the regulation of tumor cells behaviors. In vitro tumor models with appropriate matrix stiffness are urgently desired.
Yonggang Lv +3 more
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Nanomaterials, 2022 The typically-used element torsional stiffness GJ/L (where G is the shear modulus, J the St. Venant torsion constant, and L the element length) may severely underestimate the torsional stiffness of thin-walled nanostructural members, due to neglecting ...
Wen-Hao Pan +3 more
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Journal of Translational Medicine, 2022 Background Solid tumors are stiffer than their surrounding normal tissues; however, their interior stiffness is not uniform. Under certain conditions, cancer cells can acquire stem-like phenotypes.
Jiayun Wei +11 more
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Free vibration of a three-layered sandwich beam using the dynamic stiffness method and experiment [PDF]
, 2007 In this paper, an accurate dynamic stiffness model for a three-layered sandwich beam of unequal thicknesses is developed and subsequently used to investigate its free vibration characteristics.
Morishima, R. +4 more
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EFNA2 Mediates Stiffness-Regulated Hypopharyngeal Cancer Progression [PDF]
Clinical and Experimental OtorhinolaryngologyObjectives Hypopharyngeal cancer (HPC), originating from the hypopharyngeal mucosa, is associated with a poor prognosis. Extracellular matrix (ECM) stiffness is closely linked to tumor progression and patient outcomes. This study aimed to investigate the
Songqun Hu +10 more
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Tumor matrix stiffness provides fertile soil for cancer stem cells
Cancer Cell International, 2023 Matrix stiffness is a mechanical characteristic of the extracellular matrix (ECM) that increases from the tumor core to the tumor periphery in a gradient pattern in a variety of solid tumors and can promote proliferation, invasion, metastasis, drug ...
Sadegh Safaei +7 more
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