Results 21 to 30 of about 156,207 (304)

Heterogeneous matrix stiffness regulates the cancer stem-like cell phenotype in hepatocellular carcinoma

open access: yesJournal of Translational Medicine, 2022
Background Solid tumors are stiffer than their surrounding normal tissues; however, their interior stiffness is not uniform. Under certain conditions, cancer cells can acquire stem-like phenotypes.
Jiayun Wei   +11 more
doaj   +1 more source

Absence of HDAC3 by Matrix Stiffness Promotes Chromatin Remodeling and Fibroblast Activation in Idiopathic Pulmonary Fibrosis

open access: yesCells, 2023
Idiopathic pulmonary fibrosis (IPF) is a chronic and fatal disease characterized by progressive and irreversible lung scarring associated with persistent activation of fibroblasts.
Fernanda Toscano-Marquez   +3 more
doaj   +1 more source

Free vibration of a three-layered sandwich beam using the dynamic stiffness method and experiment [PDF]

open access: yes, 2007
In this paper, an accurate dynamic stiffness model for a three-layered sandwich beam of unequal thicknesses is developed and subsequently used to investigate its free vibration characteristics.
Morishima, R.   +4 more
core   +1 more source

Paradigms of endothelial stiffening in cardiovascular disease and vascular aging

open access: yesFrontiers in Physiology, 2023
Endothelial cells, the inner lining of the blood vessels, are well-known to play a critical role in vascular function, while endothelial dysfunction due to different cardiovascular risk factors or accumulation of disruptive mechanisms that arise with ...
Victor M. Aguilar   +5 more
doaj   +1 more source

Image2_Novel Brain-Stiffness-Mimicking Matrix Gel Enables Comprehensive Invasion Analysis of 3D Cultured GBM Cells.jpg

open access: yes, 2022
Glioblastoma (GBM) is the most common malignant primary brain tumor in adults, which is fast growing and tends to invade surrounding normal brain tissues.
Jin Xiong (3359327)   +12 more
core   +1 more source

EFNA2 Mediates Stiffness-Regulated Hypopharyngeal Cancer Progression [PDF]

open access: yesClinical and Experimental Otorhinolaryngology
Objectives Hypopharyngeal cancer (HPC), originating from the hypopharyngeal mucosa, is associated with a poor prognosis. Extracellular matrix (ECM) stiffness is closely linked to tumor progression and patient outcomes. This study aimed to investigate the
Songqun Hu   +10 more
doaj   +1 more source

Etiology of Oral Potentially Malignant Disorders and Squamous Cell Carcinoma Based on Cellular Stress Regulation and Matrix Stiffness

open access: yesFrontiers in Bioscience-Landmark, 2023
The oral cavity serves as the initial segment of the digestive system and is responsible for both nutritional supplementation and the mechanical breakdown of food.
Toshihiro Hasegawa   +4 more
doaj   +1 more source

A numerical study on impact and compression after impact behaviour of variable angle tow laminates [PDF]

open access: yes, 2013
Recent developments of variable angled tow (VAT) technology have indicated that variable stiffness composite laminates offer a strong potential for structural tailoring.
Dang, Thi D., Hallett, Stephen R.
core   +1 more source

Image4_Novel Brain-Stiffness-Mimicking Matrix Gel Enables Comprehensive Invasion Analysis of 3D Cultured GBM Cells.jpg

open access: yes, 2022
Glioblastoma (GBM) is the most common malignant primary brain tumor in adults, which is fast growing and tends to invade surrounding normal brain tissues.
Jin Xiong (3359327)   +12 more
core   +1 more source

Protein Phosphatase 2A Mediates YAP Activation in Endothelial Cells Upon VEGF Stimulation and Matrix Stiffness

open access: yesFrontiers in Cell and Developmental Biology, 2021
Angiogenesis is an essential process during development. Abnormal angiogenesis also contributes to many disease conditions such as tumor and retinal diseases.
Xiao Jiang   +12 more
doaj   +1 more source

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