Results 21 to 30 of about 1,695,806 (215)

Quantitative Polymerase Chain Reaction Identified a Multitude of mcr-1 to mcr-5 Genes in Fresh Cow Dung in Bangladesh: An Urgent Public Health Concern

Advances in Human Biology
Introduction: The emergence of antimicrobial resistance (AMR) in the food industry is a serious global public health threat. Colistin is frequently used as a growth promoter in livestock, which is a concern.
Shomaia Yasmin Mitu, Marnusa Binte Habib, Sumia Alam, Mamun Al Asad, Kakoli Akter, Shamsun Nahar, Brian Godman, Salequl Islam   +7 more
doaj   +2 more sources

Co-Occurrence of the mcr-1.1 and mcr-3.7 Genes in a Multidrug-Resistant Escherichia coli Isolate from China

Infection and Drug Resistance, 2020
Chongtao Du,1,* Yuyang Feng,1,* Guizhen Wang,2 Zhiyuan Zhang,1 Huimin Hu,1 Yu Yu,1 Jiayang Liu,1 Lihao Qiu,1 Hongtao Liu,1 Zhimin Guo,3 Jing Huang,3 Jiazhang Qiu1 1Key Laboratory of Zoonosis, Ministry of Education, College of Veterinary Medicine, Jilin ...
Du C, Feng Y, Wang G, Zhang Z, Hu H, Yu Y, Liu J, Qiu L, Liu H, Guo Z, Huang J, Qiu J   +11 more
doaj   +4 more sources

Rapid detection of human origin colistin-resistance genes mcr-1, mcr-3, mcr-8, mcr-10 in clinical fecal samples [PDF]

Archives of Microbiology, 2021
Plasmid-mediated colistin-resistance genes have been reported in human origin clinical samples worldwide which raises its threats to human infections. Notably, mcr-1, mcr-3, mcr-8, and mcr-10 have been reported isolated directly from clinical samples which creates more seriously threaten to human health than other mcr gene types. A multiplex polymerase
Shuangfang Hu, Ziquan Lv, Yang Wang, Jianzhong Shen, Yuebin Ke   +4 more
openaire   +5 more sources

Prevalence of mcr-type genes among colistin-resistant Enterobacteriaceae collected in 2014-2016 as part of the INFORM global surveillance program. [PDF]

PLoS ONE, 2018
A set of 908 clinically derived colistin-resistant Enterobacteriaeae isolates collected worldwide in 2014-2016 were screened for the presence of the plasmid-borne mcr-1, mcr-2, mcr-3, mcr-4 and mcr-5 genes.
Mark G Wise, Mark A Estabrook, Daniel F Sahm, Gregory G Stone, Krystyna M Kazmierczak   +4 more
doaj   +1 more source

High Fecal Prevalence of mcr-Positive Escherichia coli in Veal Calves at Slaughter in France

Antibiotics, 2022
The aim of this study was to determine the percentage of healthy veal calves carrying mcr-positive E. coli strains at the time of slaughter in France. Fecal samples were selectively screened for mcr-positive E. coli isolates using media supplemented with
Maryse Michèle Um, Véronique Dupouy, Nathalie Arpaillange, Clémence Bièche-Terrier, Frédéric Auvray, Eric Oswald, Hubert Brugère, Delphine Bibbal   +7 more
doaj   +1 more source

Epidemiology of mobile colistin resistance genes mcr-1 to mcr-9

Journal of Antimicrobial Chemotherapy, 2020
Abstract The identification of the first mobile colistin resistance (MCR) gene, mcr-1, in 2015 triggered a rash of mcr screening reports. Subsequently, nine MCR-family genes and their variants have been described. However, a comprehensive overview concerning the epidemiology of the whole MCR family, which is essential for facilitating ...
Zhuoren, Ling, Wenjuan, Yin, Zhangqi, Shen, Yang, Wang, Jianzhong, Shen, Timothy R, Walsh   +5 more
openaire   +2 more sources

Molecular epidemiology of mcr gene group [PDF]

Clinical Microbiology and Antimicrobial Chemotherapy, 2020
Colistin and polymyxin B are the “last reserve” antimicrobials for the treatment of extensively drug-resistant Gram-negative bacterial infections. The rapidly increasing prevalence of polymyxin resistance mediated by the mcr gene localized on plasmid DNA currently poses a high epidemiological threat.
Elizaveta D. Shedko, O.Yu. Timoshina, Ilya Sulejmanovich Azyzov   +2 more
openaire   +2 more sources

Virulence and antimicrobial resistance profiles of Escherichia coli encoding mcr gene from diarrhoeic weaned piglets in Korea during 2007–2016

Journal of Global Antimicrobial Resistance, 2020
Objective: This study aimed to analyse the presence of mcr genes and virulence genes in Escherichia coli (E. coli) isolates from diarrhoeic piglets between 2007–2016 in Korea. Methods: A total of 364 E.
Kyung-Hyo Do, Ho-Eun Park, Jae-Won Byun, Wan-Kyu Lee   +3 more
doaj   +1 more source

Convergence of Plasmid-Mediated tmexCD-toprJ With Critical Resistance Genes Fuels Spread of Multidrug Resistant Bacteria. [PDF]

Adv Sci (Weinh)
Global dissemination of tmexCD‐toprJ across bacterial hosts and ecological niches is accompanied by its convergence with blaKPC, blaNDM, and mcr on mobile plasmids. Recombination and acquisition of resistance modules generate distinct multidrug resistant plasmid architectures, facilitating the emergence and spread of high‐risk bacterial populations ...
Song K, Wang M, Wu X, Cai M, Li B, Wang Q, Guan X, Ding Q, Wang R, Wang H.   +9 more
europepmc   +2 more sources

mcr-1 regulatory variants

, 2023
Associated paper:    Regulatory fine-tuning and horizontal gene transfer stabilize mobile colistin resistance  Lois Ogunlana, Liam P. Shaw, Divjot Kaur, Pramod Jangir, Timothy Walsh, Stephan Uphoff, and R.C. MacLean.  Preprint version: https://doi.org/10.
Liam Shaw (5487083)
core   +1 more source