Quantitative Polymerase Chain Reaction Identified a Multitude of mcr-1 to mcr-5 Genes in Fresh Cow Dung in Bangladesh: An Urgent Public Health Concern [PDF]
Introduction: The emergence of antimicrobial resistance (AMR) in the food industry is a serious global public health threat. Colistin is frequently used as a growth promoter in livestock, which is a concern.
Shomaia Yasmin Mitu +7 more
doaj +2 more sources
The co-transfer of plasmid-borne colistin-resistant genes mcr-1 and mcr-3.5, the carbapenemase gene blaNDM-5 and the 16S methylase gene rmtB from Escherichia coli [PDF]
AbstractWe found an unusual Escherichia coli strain with resistance to colistin, carbapenem and amikacin from sewage. We therefore characterized the strain and determined the co-transfer of the resistance determinants. Whole genome sequencing was performed using both Illumina HiSeq X10 and MinION sequencers.
Haiyan Long +5 more
openaire +4 more sources
Camels (Camelus dromedarius) are known to harbor multidrug resistant Gram-negative bacteria and to be involved in the transmission of various microorganisms to humans.
Mohamed Rhouma +5 more
doaj +2 more sources
Chongtao Du,1,* Yuyang Feng,1,* Guizhen Wang,2 Zhiyuan Zhang,1 Huimin Hu,1 Yu Yu,1 Jiayang Liu,1 Lihao Qiu,1 Hongtao Liu,1 Zhimin Guo,3 Jing Huang,3 Jiazhang Qiu1 1Key Laboratory of Zoonosis, Ministry of Education, College of Veterinary Medicine, Jilin ...
Du C +11 more
doaj +4 more sources
Rapid detection of human origin colistin-resistance genes mcr-1, mcr-3, mcr-8, mcr-10 in clinical fecal samples [PDF]
Plasmid-mediated colistin-resistance genes have been reported in human origin clinical samples worldwide which raises its threats to human infections. Notably, mcr-1, mcr-3, mcr-8, and mcr-10 have been reported isolated directly from clinical samples which creates more seriously threaten to human health than other mcr gene types. A multiplex polymerase
Shuangfang Hu +4 more
openaire +5 more sources
Epidemiology of mobile colistin resistance genes mcr-1 to mcr-9
Abstract The identification of the first mobile colistin resistance (MCR) gene, mcr-1, in 2015 triggered a rash of mcr screening reports. Subsequently, nine MCR-family genes and their variants have been described. However, a comprehensive overview concerning the epidemiology of the whole MCR family, which is essential for facilitating ...
Zhuoren, Ling +5 more
openaire +2 more sources
High Fecal Prevalence of mcr-Positive Escherichia coli in Veal Calves at Slaughter in France
The aim of this study was to determine the percentage of healthy veal calves carrying mcr-positive E. coli strains at the time of slaughter in France. Fecal samples were selectively screened for mcr-positive E. coli isolates using media supplemented with
Maryse Michèle Um +7 more
doaj +1 more source
Molecular epidemiology of mcr gene group [PDF]
Colistin and polymyxin B are the “last reserve” antimicrobials for the treatment of extensively drug-resistant Gram-negative bacterial infections. The rapidly increasing prevalence of polymyxin resistance mediated by the mcr gene localized on plasmid DNA currently poses a high epidemiological threat.
Elizaveta D. Shedko +2 more
openaire +2 more sources
Rapid detection and differentiation of mobile colistin resistance (mcr-1 to mcr-10) genes by real-time PCR and melt-curve analysis [PDF]
Background The emergence of multi-drug-resistant (MDR) micro-organisms prompted new interest in older antibiotics, such as colistin, that had been abandoned previously due to limited efficacy or high toxicity.
David, S. +13 more
core +1 more source
Objective: This study aimed to analyse the presence of mcr genes and virulence genes in Escherichia coli (E. coli) isolates from diarrhoeic piglets between 2007–2016 in Korea. Methods: A total of 364 E.
Kyung-Hyo Do +3 more
doaj +1 more source

