Results 31 to 40 of about 1,822,998 (209)

Potential spread of mcr-9-carrying IncHI2 plasmids in Enterobacter hormaechei in Vietnam

open access: yesJournal of Global Antimicrobial Resistance, 2021
: Objectives: Mobile colistin resistance (mcr) genes are widely distributed around the world. To date, ten major variants of mcr genes are known (mcr-1 to mcr-10).
Van Thi Thu Ha   +7 more
doaj   +1 more source

Genetic Characterisation of Colistin Resistant Klebsiella pneumoniae Clinical Isolates From North India

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
BackgroundIncreasing use of colistin has led to the world-wide emergence of mobile colistin resistant gene (mcr). The present study aimed to identify and characterise mcr and other drug-resistant genes in colistin resistant Klebsiella pneumoniae clinical
Sanjay Singh   +7 more
doaj   +1 more source

Rapid multiplex polymerase chain reaction for detection of mcr-1 to mcr-5 genes [PDF]

open access: yesDiagnostic Microbiology and Infectious Disease, 2018
A rapid (total time 
Lescat M, Poirel L, Nordmann P
openaire   +4 more sources

Comparative genomic analysis of Colistin resistant Escherichia coli isolated from pigs, a human and wastewater on colistin withdrawn pig farm

open access: yesScientific Reports, 2023
In this study, genomic and plasmid characteristics of Escherichia coli were determined with the aim of deducing how mcr genes may have spread on a colistin withdrawn pig farm. Whole genome hybrid sequencing was applied to six mcr-positive E. coli (MCRPE)
Nwai Oo Khine   +4 more
doaj   +1 more source

Putative mobilized colistin resistance genes in the human gut microbiome

open access: yesBMC Microbiology, 2021
Background The high incidence of bacterial genes that confer resistance to last-resort antibiotics, such as colistin, caused by mobilized colistin resistance (mcr) genes, poses an unprecedented threat to human health. Understanding the spread, evolution,
Bruno G. N. Andrade   +5 more
doaj   +1 more source

Prevalence and Genetic Analysis of Chromosomal mcr-3/7 in Aeromonas From U.S. Animal-Derived Samples

open access: yesFrontiers in Microbiology, 2021
The prevalence of mcr-positive bacteria in 5,169 domestic animal-derived samples collected by USDA Food Safety and Inspection Service between October 2018 and May 2019 was investigated.
Yan Wang   +5 more
doaj   +1 more source

Characterisation of Colistin -Resistant Enterobacterales and Acinetobacter Strains Carrying mcr Genes from Asian Aquaculture Products. [PDF]

open access: yesAntibiotics (Basel), 2021
Aquaculture systems are widely recognised as hotspots for horizontal gene transfer, and the need for screening for bacteria carrying antimicrobial resistance genes in aquaculture systems is becoming more important.
Kalová A   +4 more
europepmc   +2 more sources

Convergence of Plasmid-Mediated tmexCD-toprJ With Critical Resistance Genes Fuels Spread of Multidrug Resistant Bacteria. [PDF]

open access: yesAdv Sci (Weinh)
Global dissemination of tmexCD‐toprJ across bacterial hosts and ecological niches is accompanied by its convergence with blaKPC, blaNDM, and mcr on mobile plasmids. Recombination and acquisition of resistance modules generate distinct multidrug resistant plasmid architectures, facilitating the emergence and spread of high‐risk bacterial populations ...
Song K   +9 more
europepmc   +2 more sources

Molecular Detection of the mcr Genes by Multiplex PCR.

open access: yesInfection and drug resistance, 2020
The emergence and prevalence of plasmid-mediated colistin-resistant bacterial strains in recent years have raised great concerns in clinical medicine. It is urgently needed to develop a cheaper, faster, simpler, sensitive, and specific molecular detection method to identify and monitor the dissemination of the transferable resistant determinants.Herein,
Liu,Jiayang   +10 more
openaire   +4 more sources

Emergence of mcr-9.1 in Extended-Spectrum-β-Lactamase-Producing Clinical Enterobacteriaceae in Pretoria, South Africa: Global Evolutionary Phylogenomics, Resistome, and Mobilome

open access: yesmSystems, 2020
Extended-spectrum-β-lactamase (ESBL)-producing Enterobacteriaceae are critical-priority pathogens that cause substantial fatalities. With the emergence of mobile mcr genes mediating resistance to colistin in Enterobacteriaceae, clinicians are now left ...
John Osei Sekyere   +3 more
doaj   +3 more sources

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