Results 51 to 60 of about 1,695,806 (215)

Emergence of Escherichia coli harbouring mcr-1 and mcr-3 genes in North West Algerian farmlands

Journal of Global Antimicrobial Resistance, 2020
Colistin resistance has emerged worldwide, threatening the efficacy of colistin treatment of Gram-negative bacterial infections. Farms have been recognised as an important reservoir of genes conferring resistance to colistin. This study aimed to isolate and characterise colistin-resistant bacteria in farmlands located in the region of Oran, northwest ...
Touati, Meriem, Hadjadj, Linda, Berrazeg, Meryem, Baron, Sophie, Rolain, Jean Marc   +4 more
openaire   +3 more sources

Distribution and Transmission of Colistin Resistance Genes mcr-1 and mcr-3 among Nontyphoidal Salmonella Isolates in China from 2011 to 2020

Microbiology Spectrum, 2023
Mobile colistin resistance (mcr) genes are present mainly in plasmids and can disseminate clonally or horizontally via either plasmids or insertion sequences in different genomic locations among the Enterobacteriaceae.
Tingting Yang, Weiwei Li, Qingpo Cui, Xiaoxia Qin, Bosheng Li, Xiugui Li, Huayun Jia, Xiaorong Yang, Chengwei Liu, Yang Wang, Shaolin Wang, Jianzhong Shen, Yunchang Guo, Zhangqi Shen   +13 more
doaj   +1 more source

Image_1_Occurrence of mcr-1 and mcr-2 colistin resistance genes in porcine Escherichia coli isolates (2010–2020) and genomic characterization of mcr-2-positive E. coli.pdf

, 2022
IntroductionThe global emergence of plasmid-mediated colistin resistance is threatening the efficacy of colistin as one of the last treatment options against multi-drug resistant Gram-negative bacteria.
Torsten Semmler (106650), Christa Ewers (106664), Lisa Göpel (14239190), Katharina Kerner (3563780), Ellen Prenger-Berninghoff (617468), Rolf Bauerfeind (14239193)   +5 more
core   +1 more source

Rapid detection and differentiation of mobile colistin resistance (mcr-1 to mcr-10) genes by real-time PCR and melt-curve analysis [PDF]

, 2021
Background The emergence of multi-drug-resistant (MDR) micro-organisms prompted new interest in older antibiotics, such as colistin, that had been abandoned previously due to limited efficacy or high toxicity.
Sands, K, Khan, S, David, S., Turner, L., Wootton, M., Khan, S., Turner, L, Mentasti, M, Wootton, M, Davies, L, David, S, Sands, K., Mentasti, M., Davies, L.   +13 more
core   +1 more source

Global Dissemination of the mcr-1 gene

Archives of Pediatric Infectious Diseases, 2016
: Antimicrobial resistance is one of the most severe threats to human health. The first report of plasmid-mediated colistin resistance in Escherichia coli from animals, food, and humans was in 2015 from China. The current increasing trend of resistance is extremely troubling because polymyxins are the last-resort antibiotics for treating infections with
Soroor Erfanimanesh, Ali Hashemi
openaire   +1 more source

Molecular mechanisms of polymyxin resistance and detection of mcr genes [PDF]

Biomedical Papers, 2019
Antibiotic resistance is an ever-increasing global problem. Major commercial antibiotics often fail to fight common bacteria, and some pathogens have become multi-resistant. Polymyxins are potent bactericidal antibiotics against gram-negative bacteria.
Mlynárčik, Patrik, Kolář, Milan
openaire   +4 more sources

Occurrence and Characteristics of Mcrs among Gram-Negative Bacteria Causing Bloodstream Infections of Infant Inpatients between 2006 and 2019 in China

Microbiology Spectrum, 2022
The aim of this study was to determine the occurrence of mobilized colistin resistance (mcr) genes in Gram-negative bacteria causing bloodstream infections of child inpatients in China.
Lijuan Wu, Tingting Xu, Yang Ji, Jingjie Song, Feiling Wang, Junxi Huang, Kai Zhou   +6 more
doaj   +1 more source

Image_1_The occurrence and molecular detection of mcr-1 and mcr-5 genes in Enterobacteriaceae isolated from poultry and poultry meats in Malaysia.pdf

, 2023
The advent of antimicrobials-resistant (AMR), including colistin-resistant bacteria, poses a significant challenge to animal and human health, food safety, socio-economic growth, and the global environment.
Md Rezaul Karim (5263895), Nur Indah Ahmad (7460207), Nik Mohd Faiz (16736982), Zunita Zakaria (310270), Latiffah Hassan (310272)   +4 more
core   +1 more source

Molecular Genetic Characteristics of Plasmid-Borne mcr-9 in Salmonella enterica Serotype Typhimurium and Thompson in Zhejiang, China

Frontiers in Microbiology, 2022
Salmonella enterica is a zoonotic food-borne pathogen threatening public health around the world. As is the case with many other pathogens, the spread of mobilized colistin resistance (mcr) alleles is of grave concern. In this study, totally 689 clinical
Jianzhong Fan, Heng Cai, Heng Cai, Heng Cai, Youhong Fang, Jintao He, Jintao He, Jintao He, Linghong Zhang, Linghong Zhang, Linghong Zhang, Qingye Xu, Yunxing Yang, Sebastian Leptihn, Sebastian Leptihn, Yunsong Yu, Yunsong Yu, Yunsong Yu, Dongdong Zhao, Dongdong Zhao, Dongdong Zhao, Xiaoting Hua, Xiaoting Hua, Xiaoting Hua   +23 more
doaj   +1 more source

Water‐Activated Phospholipid Phase‐Separation Gel as an Immunomodulatory Anti‐Adhesion Barrier for Postoperative Adhesion Prevention

Advanced Healthcare Materials, EarlyView.
A water‐activated phospholipid phase‐separation gel is repurposed as a drug‐free surgical barrier for postoperative adhesion prevention. Propylene glycol promotes rapid lamellar gel reinforcement, prolonged local retention, and tissue coverage, while phosphatidylcholine‐mediated immunomodulation suppresses inflammatory and fibrotic responses. This dual‐
Jong‐Ju Lee, Yulseung Sung, Yeji Kim, Heesang Yang, Suyeon Pyo, Byeol Yun, Sung‐Joo Hwang   +6 more
wiley   +1 more source