Results 51 to 60 of about 1,822,998 (209)
Epidemiology of mobile colistin resistance (mcr) genes in aquatic environments
Journal of Global Antimicrobial Resistance, 2021 Colistin is one of the last-line therapies against multidrug-resistant Gram-negative pathogens, especially carbapenemase-producing isolates, making resistance to this compound a major global public-health crisis. Until recently, colistin resistance in Gram-negative bacteria was known to arise only by chromosomal mutations.
Cherak, Zineb +3 more
openaire +4 more sources
, 2022 IntroductionThe global emergence of plasmid-mediated colistin resistance is threatening the efficacy of colistin as one of the last treatment options against multi-drug resistant Gram-negative bacteria.
Torsten Semmler (106650) +5 more
core +1 more source
Emergence of Escherichia coli harbouring mcr-1 and mcr-3 genes in North West Algerian farmlands
Journal of Global Antimicrobial Resistance, 2020 Colistin resistance has emerged worldwide, threatening the efficacy of colistin treatment of Gram-negative bacterial infections. Farms have been recognised as an important reservoir of genes conferring resistance to colistin. This study aimed to isolate and characterise colistin-resistant bacteria in farmlands located in the region of Oran, northwest ...
Touati, Meriem +4 more
openaire +3 more sources
Microbiology Spectrum, 2023 Mobile colistin resistance (mcr) genes are present mainly in plasmids and can disseminate clonally or horizontally via either plasmids or insertion sequences in different genomic locations among the Enterobacteriaceae.
Tingting Yang +13 more
doaj +1 more source
Global Dissemination of the mcr-1 gene
Archives of Pediatric Infectious Diseases, 2016 : Antimicrobial resistance is one of the most severe threats to human health. The first report of plasmid-mediated colistin resistance in Escherichia coli from animals, food, and humans was in 2015 from China. The current increasing trend of resistance is extremely troubling because polymyxins are the last-resort antibiotics for treating infections with
Soroor Erfanimanesh, Ali Hashemi
openaire +1 more source
Molecular mechanisms of polymyxin resistance and detection of mcr genes [PDF]
Biomedical Papers, 2019 Antibiotic resistance is an ever-increasing global problem. Major commercial antibiotics often fail to fight common bacteria, and some pathogens have become multi-resistant. Polymyxins are potent bactericidal antibiotics against gram-negative bacteria.
Mlynárčik, Patrik, Kolář, Milan
openaire +4 more sources
, 2022 IntroductionThe global emergence of plasmid-mediated colistin resistance is threatening the efficacy of colistin as one of the last treatment options against multi-drug resistant Gram-negative bacteria.
Torsten Semmler (106650) +5 more
core +1 more source
Rapid detection and quantification of plasmid-mediated colistin resistance genes (mcr-1 to mcr-5) by real-time PCR in bacterial and environmental samples [PDF]
, 2020 Aim: The aim of the study was to validate a rapid method to detect and quantify colistin resistance genes (mcr-1 to mcr-5) by real-time polymerase chain reaction (RT-PCR) in diverse matrices. Methods and results: The detection limit of two newly designed
Grilli G. +13 more
core +1 more source
Microbiology Spectrum, 2022 The aim of this study was to determine the occurrence of mobilized colistin resistance (mcr) genes in Gram-negative bacteria causing bloodstream infections of child inpatients in China.
Lijuan Wu +6 more
doaj +1 more source
Microbiology Spectrum, 2022 Mobile colistin resistance (mcr) genes mediated by plasmids have widely disseminated throughout the world. Recently, 10 mcr genes (mcr-1 to mcr-10) and a large number of variants have been identified in more than 60 countries.
Yi Yin +6 more
doaj +1 more source