Results 141 to 150 of about 43,753 (301)
Novel Organelle‐Based Intracellular Immunity With Mechanistic and Therapeutic Implications
Barrier Immunity, EarlyView.A conceptual framework illustrating how PAMPs/DAMPs initiate barrier, innate, adaptive, and intracellular immune responses, with organelle‐based intracellular immunity serving as a central integrator linking metabolism, inflammatory signaling, and therapeutic interventions to restore immune homeostasis.
Keman Xu +9 more
wiley +1 more source
Pengaruh Konsentrasi Ekstrak Etanol Daun Salam (Syzygium Polyanthum) Terhadap Hambatan Pertumbuhan Bakteri Enterococcus Faecalis Dominan di Saluran Akar In Vitro [PDF]
, 2015 Enterococcus faecalis is a Gram-positive anaerobic bacteria which usually found on periapical lesion. It is known as phatogenic bacteria often cause failure on root canal treatment. Herbs usage as an antibacterial agent has been widely applied by people,
, drg. Mahmud Kholifa, MDSc +2 more
core
iMetaMed, EarlyView.This study employed multi‐omics approaches to investigate the regulatory mechanism of Mycobacterium PknG on host cell processes. We found that host lysine‐tRNA ligase (KARS) is a potential substrate of PknG; and PknG can regulate the immune response by catalyzing the phosphorylation of KARS at T592 and T595 sites, affecting the phosphorylation level in
Nana Tian +13 more
wiley +1 more source
Perbedaan Pasta Gigi dengan dan Tanpa Tambahan Ekstrak Etanol Daun Belimbing Wuluh (Averrhoa Bilimbi L.) Konsentrasi 10,5% Terhadap Hambatan Pertumbuhan Streptococcus Mutans [PDF]
, 2015 Streptococcus mutans is known as the main bacteria causes dental caries. Dental caries can be avoided by applying toothpaste contains antibacteria and this antibacteria ability can be enhanced by adding herbal materials with 10,5% consentration of ...
, drg. Mahmud Kholifa, MDSc +2 more
core
iNew Medicine, EarlyView.ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu +5 more
wiley +1 more source
iNew Medicine, EarlyView.ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid +4 more
wiley +1 more source
N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential
iNew Medicine, EarlyView.ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen +6 more
wiley +1 more source
Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure
Journal of Applied Toxicology, EarlyView.ABSTRACT The tumor microenvironment (TME) influences prostate cancer (PCa) progression through stromal and immune interactions. Adipose‐derived mesenchymal stromal cells (ASCs) modulate immune tone, while inorganic arsenic (iAs), a widespread toxicant, is linked to immune suppression and carcinogenesis.
Joseph J. Shearer +4 more
wiley +1 more source
Journal of Clinical Laboratory Analysis, EarlyView.This study utilizes a two‐sample Mendelian randomization framework to establish a causal link between circulating inflammatory proteins, blood metabolites, and the risk of serous ovarian carcinoma. Our findings identify Interleukin‐8 as a significant risk factor and demonstrate that 1‐Palmitoyl‐GPG (16:0) acts as a metabolic mediator within this ...
Chong‐ze Yang +6 more
wiley +1 more source