Results 221 to 230 of about 36,927 (297)

Chronic Scrotal Content Pain: A Practical Guide to Diagnosis and Management

Trends in Urology &Men's Health, Volume 17, Issue 6, December 2026.
ABSTRACT Chronic scrotal content pain (CSCP) is a common but often poorly understood condition that presents a significant diagnostic and therapeutic challenge. The broad differential diagnosis and frequent absence of an identifiable cause can lead to repeated investigations, delayed treatment and unnecessary surgery.
Mahin Chowdhury, Mohammad Arabiyat, Ibrahim Abuelbeh, Theodora Stasinou, Peter Grice, Vaibhav Modgil, Ian Pearce   +6 more
wiley   +1 more source

XBP1 signaling from tumor metabolic stress to myeloid driven immunotherapy resistance (Review). [PDF]

Int J Mol Med
Chen Z, Wu J, Liu W, Tan J, Peng X, Zhang Y, Liang G.   +6 more
europepmc   +1 more source

Further Insights Into the Mechanisms of Lymph Node Metastasis

Cancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Metastasis of malignant tumors arising from epithelial organs to sentinel lymph nodes has important implications for prognosis, staging, and therapeutic decision‐making. Recent insights into anatomic pathways, pathogenesis, molecular interactions, and genetic factors have encouraged scientists and clinicians to develop drugs that target ...
S. David Nathanson, Meghan J. O'Melia, Kelly C. Rosso, Ian S. Wood, Drishti Lall, Jenny T. Bui   +5 more
wiley   +1 more source

Myeloid-Derived Suppressor Cells: Function, Migration, and Therapeutic Opportunities in Glioblastoma. [PDF]

Cells
Figg JW, Love C, West I, Jin D, Engelbart M, Ware D, Bessey R, Flores CT.   +7 more
europepmc   +1 more source

RNA‐Binding Protein NOVA1 Restrains Immune Escape and Liver Metastasis in Colorectal Cancer via Stabilizing NRXN1 mRNA

The Journal of Gene Medicine, Volume 28, Issue 11, November 2026.
The RNA‐binding protein neuro‐oncological ventral antigen 1 (NOVA1) is downregulated in colorectal cancer (CRC) and is associated with poor prognosis. NOVA1 binds and stabilizes neurexin 1 (NRXN1) messenger RNA (mRNA), thereby increasing NRXN1 expression and suppressing tumor cell proliferation, invasion, immune evasion, and liver metastasis; NRXN1 ...
ZhiXing Wei, Xing Wei, LinSai Cui, YaXin Pang, Guang Cui, Zhen Wei, ZhaoCai He, BuQiang Wu   +7 more
wiley   +1 more source

RelB/ILF2-GM-CSF loop sustains tumor-MDSC communication in prostate cancer immunosuppression. [PDF]

Cell Death Dis
Xu F, Li M, Zhang Y, Xu Z, Yin Q, Zhang S, Wu F, Ma Y, Jia Z, Wang X, Dong J, Zhou Z, Li JJ, Li X, Zhang Y.   +14 more
europepmc   +1 more source

Exosomes in Cancer: The Biology, Function, Diagnosis, and Therapy

MedComm, Volume 7, Issue 11, November 2026.
Tumor‐derived exosomes and nonmembranous extracellular nanoparticles (exomeres/supermeres) constitute a heterogeneous communication network that drives cancer progression. By shuttling functional biomolecules across tissue‐specific barriers, these nanoparticles orchestrate local microenvironmental remodeling, immune suppression, premetastatic niche ...
Jun Wu, Lei Wu, Kang Yang, Kang Xie, Tao Lu, Tiangxiang Huang, Dengfeng Wan, Tao Song, Longbo Zhang   +8 more
wiley   +1 more source

Neutrophils: Heterogeneity, Biology, Diseases, and Therapeutic Strategies

MedComm, Volume 7, Issue 11, November 2026.
Neutrophils exhibit remarkable functional plasticity and play dual roles in tissue protection and disease progression. This review summarizes their key biological functions and highlights the shift from conventional broad‐spectrum interventions to neutrophil‐based drug delivery systems.
Yibing Zhang, Siwen Wu, Yusi Wang, Die Hu, Li Yang   +4 more
wiley   +1 more source

Myeloid-derived suppressor cells in multiple myeloma: mechanistic insights and therapeutic implications. [PDF]

Front Immunol
Wen J, Zhou Q, Yue J, Zhang Y, Zheng Y, Xu F.   +5 more
europepmc   +1 more source