Results 31 to 40 of about 51,191 (308)
Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards [PDF]
, 2016 Myeloid-derived suppressor cells (MDSCs) have emerged as major regulators of immune responses in cancer and other pathological conditions. In recent years, ample evidence supports key contributions of MDSC to tumour progression through both immune ...
Brandau, Sven +14 more
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OncoImmunology, 2017 CD39/CD73-adenosine pathway has been recently defined as an important tumor-induced immunosuppressive mechanism. We here documented a fraction of CD11b+CD33+ myeloid-derived suppressor cells (MDSCs) in peripheral blood and tumor tissues from non-small ...
Jieyao Li +21 more
doaj +1 more source
Frontiers in Oncology, 2023 PurposeMalignant head and neck squamous cell carcinoma (HNSCC) is characterized by a poor prognosis and resistance to conventional radiotherapy. Infiltrating myeloid-derived suppressive cells (MDSCs) is prominent in HNSCC and is linked to immune ...
Chun-Hsiang Chang +7 more
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Immunotherapy of targeting MDSCs in tumor microenvironment
Frontiers in Immunology, 2022 Myeloid-derived suppressor cells (MDSCs) are a group of heterogeneous cells which are abnormally accumulated during the differentiation of myeloid cells. Immunosuppression is the main functional feature of MDSCs, which inhibit T cell activity in the tumor microenvironment (TME) and promote tumoral immune escape.
Hongshu Sui +14 more
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Frontiers in Immunology, 2021 The accumulation of myeloid-derived suppressor cells (MDSCs) is one of the major obstacles to achieve an appropriate anti-tumor immune response and successful tumor immunotherapy.
Quan Yang +16 more
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Beyond the immune suppression: the immunotherapy in prostate cancer [PDF]
, 2015 Prostate cancer (PCa) is the second most common cancer in men.Aswell in many other human cancers, inflammation and immune suppression have an important role in their development.We briefly describe the host components that interact with the tumor to ...
Agliano', Anna Maria +4 more
core +3 more sources
Editorial: HDAC inhibition begets more MDSCs [PDF]
Journal of Leukocyte Biology, 2012 Discussion on HDAC inhibition-mediated immune-regulation and generating MDSCs with greater efficiency, both in vitro and in vivo.
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Cancer Management and Research, 2021 Qiannan Yang,1,* Bojun Yu,1,* Jiuhong Kang,2 Ang Li,2 Jing Sun1 1Department of Gynecology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, 200092, People’s Republic of China; 2Clinical and ...
Yang Q, Yu B, Kang J, Li A, Sun J
doaj
Stem Cell Research & Therapy, 2020 Background Mesenchymal stem cells (MSCs) can regulate innate and adaptive immune systems through interacting with immune cells directly and secreting multiple soluble factors.
Jingjing Qi +5 more
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Move over Tregs, MDSCs are here [PDF]
Blood, 2016 In this issue of Blood, Hou et al show the involvement of myeloid-derived suppressor cells (MDSCs) in the pathogenesis of immune thrombocytopenia (ITP) and identify a novel mechanism by which high-dose dexamethasone (HD-DXM) promotes MDSC expansion and function and correlates with increased platelet counts.
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