Results 11 to 20 of about 51,191 (308)
International Immunopharmacology, 2011 Myeloid derived suppressor cells (MDSC) were first described nearly two decades ago. Until recently, however, descriptions of MDSC populations were found almost exclusively in animal models of cancer or in cancer patients. Over the last few years, an increasing number of reports have been published describing populations of myeloid cells with MDSC-like
James G, Cripps, James D, Gorham
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AIDS, 2012 Myeloid-derived suppressor cells (MDSCs) were initially described more than 2 decades ago as bone marrow suppressor cells in mice with metastatic lung tumors [1]. In the past several years, there has been increasing interest in their role in cancer immune regulation [2,3].
Bernard J C, Macatangay +2 more
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Fatal attraction: TICs and MDSCs [PDF]
Cell Cycle, 2016 We recently observed that the propensity to induce MDSC accumulation varies greatly between different mammary tumors.
Thomas, Welte +2 more
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Proceedings of the 14th IEEE/ACM International Conference on Utility and Cloud Computing Companion, 2021 The growth of the Internet of Things is resulting in an explosion of data volumes at the Edge of the Internet. To reduce costs incurred due to data movement and centralized cloud-based processing, it is becoming increasingly important to process and analyze such data closer to the data sources.
Balouek-Thomert, Daniel +5 more
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Transcriptomic profiling disclosed the role of DNA methylation and histone modifications in tumor-infiltrating myeloid-derived suppressor cell subsets in colorectal cancer [PDF]
, 2020 Increased numbers of myeloid-derived suppressor cells (MDSCs) are positively correlated with poor prognosis and reduced survivals of cancer patients. They play central roles in tumor immune evasion and tumor metastasis.
Abu Nada, M +9 more
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Role of Rip2 in development of tumor-infiltrating MDSCs and bladder cancer metastasis. [PDF]
, 2014 Tumor invasion and metastases represent a complex series of molecular events that portends a poor prognosis. The contribution of inflammatory pathways mediating this process is not well understood. Nod-like receptors (NLRs) of innate immunity function as
Chin, Arnold I, Zhang, Hanwei
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Signaling pathways involved in MDSC regulation [PDF]
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2014 The immune system has evolved mechanisms to protect the host from the deleterious effects of inflammation. The generation of immune suppressive cells like myeloid derived suppressor cells (MDSCs) that can counteract T cell responses represents one such strategy.
Prashant, Trikha, William E, Carson
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Myeloid-Derived Suppressor Cells (MDSCs) in Haematology [PDF]
Journal of Clinical Medicine, 2021 Myeloid-derived suppressor cells (MDSCs) are immature myeloid cells with immunomodulating properties, mainly acting by suppressing T-cell responses [...]
Nikoleta Bizymi, Helen A. Papadaki
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Dickkopf-related protein 1 (Dkk1) regulates the accumulation and function of myeloid derived suppressor cells in cancer [PDF]
, 2016 Tumor–stroma interactions contribute to tumorigenesis. Tumor cells can educate the stroma at primary and distant sites to facilitate the recruitment of heterogeneous populations of immature myeloid cells, known as myeloid-derived suppressor cells (MDSCs).
Ali Zamani +43 more
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Clinical significance of plasmacytoid dendritic cells and myeloid-derived suppressor cells in melanoma [PDF]
, 2015 Background: Immune markers in the peripheral blood of melanoma patients could provide prognostic information. However, there is currently no consensus on which circulating cell types have more clinical impact.
Bachert, Claus +8 more
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