Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Meaningfulness in work – Experiences among employed individuals with persistent mental illness
, 2009 The aim of the present study was to investigate how people with persistent mental illness, with various types of work and employment conditions, experience and describe the meaningfulness of work.
Leufstadius, Christel +2 more
core
Effectiveness of using Scenario Based Learning Strategy for Nurse’ Managers Cognitive Flexibility on Nurses’ Organizational Excellence and Meaningfulness of Work [PDF]
Egyptian Journal of Health CareImplementing a training program based on the organizational cognitive felxibility using new methods of teaching as secnario based learning for nurse managers significantly improves organizational effectiveness in healthcare settings as organizational ...
Mona Thabet +2 more
doaj +1 more source
Funeral and Mortuary Operators: The Role of Stigma, Incivility, Work Meaningfulness and Work-Family Relation to Explain Occupational Burnout. [PDF]
Int J Environ Res Public Health, 2021 Guidetti G +6 more
europepmc +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Job crafting, work meaningfulness and organizational commitment among school principals
, 2023 Tavoitteet. Tämän tutkimuksen tavoitteena oli tutkia työn muokkaamisen yhteyttä rehtoreiden kokemaan työn merkityksellisyyteen ja työhön sitoutumiseen.
Koskinen, Tytti
core
The effects of job crafting on subjective well-being amongst South African high school teachers
SA Journal of Industrial Psychology, 2016 Orientation: Job crafting can result in a number of positive outcomes for teachers, such as increased meaningfulness and engagement at work. Increased work engagement and psychological meaningfulness may yield positive benefits for the practice of ...
Sergio Peral, Madelyn Geldenhuys
doaj +1 more source
"The Power of a Firm's Benevolent Act": The Influence of Work Overload on Turnover Intention, the Mediating Role of Meaningfulness of Work and the Moderating Effect of CSR Activities. [PDF]
Int J Environ Res Public Health, 2021 Hwang YS, Kim BJ.
europepmc +1 more source