Results 121 to 130 of about 67,182 (234)

Curcumin ameliorates oxaliplatin-induced allodynia response and melanocortin downregulation in the spinal cord

Research Results in Pharmacology
Introduction: Oxaliplatin is a platinum-based chemotherapy agent that often causes chemotherapy-induced peripheral neuropathy (CIPN). This effect limits the potential activity and decreases the cancer patient’s quality of life. Melanocortin and transient
Alma Nuril Aliya, Luke Wongso, Diah Ayu Wakita Trimanda , Risda Maulida, I Nengah Budi Sumartha, Samirah Samirah, Abdulloh Machin, Long Chiau Ming, Abdelhakim Bouyahya, Mahardian Rahmadi, Junaidi Khotib, Сhrismawan Ardianto   +11 more
doaj   +1 more source

Old drugs with new skills: fenoprofen as an allosteric enhancer at melanocortin receptor 3 [PDF]

, 2016
This project was supported by Queen Mary Innovation Ltd Proof of Concept Fund (2012/13) and The William Harvey Research ...
Cook, JM, Forfar, RAE, Jerman, JC, Montero-Melendez, T, Perretti, M, Taylor, DL   +5 more
core   +1 more source

Development of the Hypothalamic Melanocortin System

Frontiers in Endocrinology, 2013
The melanocortin system is a critical component of the forebrain and hindbrain regulatory systems involved in energy balance. This system is composed of pro-opiomelanocortin (POMC) neurons that act, in part, through the melanocortin-4 receptor (MC4R ...
Berengere eCoupe, Sebastien G Bouret
doaj   +1 more source

A Brain-Melanocortin-Vagus Axis Mediates Adipose Tissue Expansion Independently of Energy Intake

Cell Reports, 2019
Summary: The melanocortin system is a brain circuit that influences energy balance by regulating energy intake and expenditure. In addition, the brain-melanocortin system controls adipose tissue metabolism to optimize fuel mobilization and storage ...
Jenna Holland, Joyce Sorrell, Emily Yates, Kathleen Smith, Shahriar Arbabi, Myrtha Arnold, Marita Rivir, Rachel Morano, Jenny Chen, Xiang Zhang, Richard Dimarchi, Stephen C. Woods, Joan Sanchez-Gurmaches, Eric Wohleb, Diego Perez-Tilve   +14 more
doaj   +1 more source

Hormonal and Neuroendocrine Regulation of Energy Balance

Frontiers in Physiology, 2016
Maria eMoreno, Antonia eLanni
doaj   +1 more source

The Calbindin-D28k binding site on inositol monophosphatase may allow inhibition independent of the lithium site of action [PDF]

, 2011
Among numerous reported biochemical effects the lithium-inhibitable enzyme inositol-monophosphatase (IMPase) remains a viable target for lithium's therapeutic mechanism of action.
Amnon Hoffman, Chaim Gilon, Galila Agam, Itshak Levi, Joseph Fanous, Miriam Eisenstein, Orna Almog, Yael Askira, Yftah Talgan   +8 more
core   +1 more source

Magel2 in hypothalamic POMC neurons influences the impact of stress on anxiety-like behavior and spatial learning associated with a food reward in male mice

Frontiers in Neural Circuits
IntroductionPrader-Willi syndrome (PWS) results from a lack of expression in several paternally inherited, imprinted contiguous genes. Among the genes inactivated in PWS, the Magel2 gene is considered a significant contributor to the etiology of the ...
Sangbhin Lee, Sangbhin Lee, Young-Hwan Jo, Young-Hwan Jo, Young-Hwan Jo, Young-Hwan Jo   +5 more
doaj   +1 more source

Melanocortin receptors

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017
openaire   +2 more sources

Cellular signatures of melanocortin pathway genes across the locus coeruleus. [PDF]

Acta Neuropathol Commun
Basak A, Erol FMB, De Rosa MC, Dong Z, Ogbolu V, Glover HJ, Rausch R, Hargus G, Creus-Muncunill J, Buchanan H, Bai Y, Su Q, Chang B, Adler C, Flaherty D, Ciener B, Xiao H, Reddy H, Aime-Wilson P, Reitz C, Sleeman MW, Altarejos JY, Leibel RL, Qiang LO, Teich AF, Doege CA.   +25 more
europepmc   +1 more source

Glucose Intake during the Neonatal Period Modulates the Central Melanocortin System with Breed-Specific Differences. [PDF]

J Poult Sci
Kimura K, Watanabe Y, Ashizawa S, Matsushita K, Nakao N, Ohta Y, Shiraishi JI.   +6 more
europepmc   +1 more source