Results 131 to 140 of about 57,827 (240)

Melanocortin-4 Receptor in Fish: A Review

, 2017
The melanocortin-4 receptor (MC4R) belongs to the melanocortin system, has been well investigated in mammals. Which plays important roles in several physiological processes, such as regulating energy homeostasis, cachexia, cardiovascular function ...
Zheng-Yong Wen, Yuan-Chao Zou, ZY Wen, Deng-Yue Yuan, Chuan-Jie Qin, Rui Li   +5 more
core   +1 more source

The last‐step integrator thesis: Heterarchical control of the mammalian gastrointestinal tract

The Journal of Physiology, Volume 604, Issue 20, Page 8323-8344, 15 October 2026.
Abstract figure legend Heterarchy of control of the gastrointestinal tract. The production mechanisms (i.e. epithelial cells and muscles) are shown at the bottom in green. Above them are some of the many mechanisms that provide control inputs to these production mechanisms.
William Bechtel, Leonardo Bich
wiley   +1 more source

Magel2 in hypothalamic POMC neurons influences the impact of stress on anxiety-like behavior and spatial learning associated with a food reward in male mice

Frontiers in Neural Circuits
IntroductionPrader-Willi syndrome (PWS) results from a lack of expression in several paternally inherited, imprinted contiguous genes. Among the genes inactivated in PWS, the Magel2 gene is considered a significant contributor to the etiology of the ...
Sangbhin Lee, Sangbhin Lee, Young-Hwan Jo, Young-Hwan Jo, Young-Hwan Jo, Young-Hwan Jo   +5 more
doaj   +1 more source

Asp10 in Lys gamma2 MSH determines selective activation of the melanocortin MC3 receptor

, 1998
The melanocortin MC3 and MC4 receptors are the main melanocortin receptors expressed in brain. Of the endogenous melanocortins, 2-melanocortin stimulating hormone (MSH) selectively activates the melanocortin MC3 receptor, whereas - and -MSH activate all ...
Oosterom, J., Adan, R.A.H., Gispen, W.H., Burbach, J.P.H.   +3 more
core  

Arthritic diseases: melanocortin type 3 receptor agonists as potential therapeutics

, 2001
Gouty arthritis is currently treated with drugs that have an array of side effects. Therefore, identification of novel endogenous targets for drug development may have beneficial properties ACTH4-10, a heptapeptide fragment derived from the hormone ...
Perretti, M., Getting, S.J.
core  

Melanocortin peptides prevent the ischemia and reperfusion-induced myocardial damage.

, 2001
Melanocortin peptides prevent the ischemia and reperfusion-induced myocardial ...
BAZZANI, Carla, GUARINI, Salvatore, BERTOLINI, Alfio, Ferrazza G., BINI, Anna, TOMASI, Aldo, MIONI, Chiara, CAINAZZO, Maria Michela, Botticelli A., ZAFFE, Davide   +9 more
core  

Melanocortin receptors

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017
openaire   +2 more sources

The Synthetic Melanocortin Agonist NDP-MSH Ameliorates THSD7A-Associated Membranous Nephropathy in an Active Immunization Mouse Model. [PDF]

FASEB J
Zhang M, Chen M, Ge Y, Gunning W, Gong R.   +4 more
europepmc   +1 more source

Cardiometabolic regulation by adipocyte-derived leptin and the brain melanocortin system. [PDF]

Clin Sci (Lond)
Hall JE, Omoto ACM, do Carmo JM, da Silva AA, Mouton AJ, Wang Z, Hall ME.   +6 more
europepmc   +1 more source

Genetic variants of the leptin-melanocortin pathway in a clinically selected Greek cohort with severe early-onset obesity and hyperphagia: implications for precision obesity medicine. [PDF]

Obes Pillars
Kostopoulou E, Spilioti DX, Pantzaris ND, Kehagias I, Kehagias D, Markantes G, Papachatzi E, Georgopoulos N, Spiliotis BE.   +8 more
europepmc   +1 more source