Results 111 to 120 of about 57,827 (240)

Striking Suture Zone Mismatch Between Nuclear and Mitochondrial Markers in North African Chalcides ocellatus (Squamata: Scincidae)

Zoologica Scripta, Volume 55, Issue 6, Page 795-804, November 2026.
ABSTRACT Linnaean and Wallacean shortfalls remain pervasive even among common and widespread Mediterranean taxa, limiting our understanding of evolutionary history and species boundaries. The Ocellated Skink Chalcides ocellatus complex illustrates this issue, with disputed subspecific taxonomy and deep mitochondrial divergences across North Africa and ...
Paul Doniol‐Valcroze, Dave Lutgen, Menad Beddek, Boualem Dellaoui, Philippe Geniez, Olivier Peyre, Patricia Sourrouille, Pierre‐André Crochet   +7 more
wiley   +1 more source

Curcumin ameliorates oxaliplatin-induced allodynia response and melanocortin downregulation in the spinal cord

Research Results in Pharmacology
Introduction: Oxaliplatin is a platinum-based chemotherapy agent that often causes chemotherapy-induced peripheral neuropathy (CIPN). This effect limits the potential activity and decreases the cancer patient’s quality of life. Melanocortin and transient
Alma Nuril Aliya, Luke Wongso, Diah Ayu Wakita Trimanda , Risda Maulida, I Nengah Budi Sumartha, Samirah Samirah, Abdulloh Machin, Long Chiau Ming, Abdelhakim Bouyahya, Mahardian Rahmadi, Junaidi Khotib, Сhrismawan Ardianto   +11 more
doaj   +1 more source

Ciliary Membrane Lipid Homeostasis in Health and Disease

Advanced Science, Volume 13, Issue 58, 19 October 2026.
This review systematically delineates the distinct lipid landscapes of ciliary membranes, including the spatial organization of phosphoinositides, cholesterol, and sphingolipids. It elucidates how these lipids orchestrate ciliogenesis, signal transduction, and membrane dynamics in cilia beating, and highlights how their dysregulation drives ...
Zhenzhou Huang, Yuan‐yuan Liu, Hanqi Sun, Peiwei Liu   +3 more
wiley   +1 more source

Health‐Related Quality of Life, Everyday Executive Functioning, and Eating Behavior in Adults With Bardet–Biedl Syndrome

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2279-2288, October 2026.
ABSTRACT Bardet–Biedl syndrome (BBS) is a rare genetic condition with a broad phenotypic spectrum. Knowledge about quality of life, executive functioning, and eating behavior in adults with BBS remains limited. This study aimed to assess health‐related quality of life (HRQoL), everyday executive functioning, and eating behavior in adults with BBS and ...
Cecilie Fremstad Rustad, Charlotte von der Lippe, Hilde Nordgarden, Jeanette Ullmann Miller, Mina Susanne Weedon‐Fekjær, Ragnheidur Bragadottir, Solrun Sigurdardottir   +6 more
wiley   +1 more source

Melanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation

, 2010
The melanocortin 1 receptor gene is a main determinant of human pigmentation, and a melanoma susceptibility gene, because its variants that are strongly associated with red hair color increase melanoma risk. To test experimentally the association between
Sartor, Maureen, Abdel-Malek, Zalfa A., Wakamatsu, Kazumasa, Shosuke Ito, Prashiela Manga, Swope, Viki, Dorothy Supp, Kavanagh, Renny J., Cassidy, Pamela, Kadekaro, Ana Luisa, Schwemberger, Sandy, Koshoffer, Amy, Zalfa A. Abdel‐Malek, Boissy, Raymond E., Viki Swope, Ana Luisa Kadekaro, Raymond E. Boissy, Maureen Sartor, Sancy Leachman, Ito, Shosuke, Kazumasa Wakamatsu, Babcock, George, Pamela Cassidy, George Babcock, Richard A. Sturm, Leachman, Sancy, Renny J. Kavanagh, Supp, Dorothy, Sturm, Richard A., Sandy Schwemberger, Manga, Prashiela, Amy Koshoffer   +31 more
core   +1 more source

A Brain-Melanocortin-Vagus Axis Mediates Adipose Tissue Expansion Independently of Energy Intake

Cell Reports, 2019
Summary: The melanocortin system is a brain circuit that influences energy balance by regulating energy intake and expenditure. In addition, the brain-melanocortin system controls adipose tissue metabolism to optimize fuel mobilization and storage ...
Jenna Holland, Joyce Sorrell, Emily Yates, Kathleen Smith, Shahriar Arbabi, Myrtha Arnold, Marita Rivir, Rachel Morano, Jenny Chen, Xiang Zhang, Richard Dimarchi, Stephen C. Woods, Joan Sanchez-Gurmaches, Eric Wohleb, Diego Perez-Tilve   +14 more
doaj   +1 more source

Streamlining Diagnosis of Bardet–Biedl Syndrome: New Diagnostic Algorithm With Updated Criteria

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2181-2198, October 2026.
ABSTRACT Considerable advances have been made in our understanding of Bardet–Biedl syndrome (BBS), particularly in its core clinical features and molecular genetics, warranting an update to the existing diagnostic criteria framework. Using a rigorous, evidence‐based, and consensus‐driven process, a multidisciplinary group of international experts and ...
Jeremy J. Pomeroy, Jesse Richards, Brooke R. Sweeney, Seema Kumar, Katie E. Queen, Joshua Zaritsky, Carl H. Cramer, Elias I. Traboulsi, Brittni A. Scruggs, Erica E. Davis, Ekaterina Keifer, Emma McGibbon, Timothy Ogden, Bendert De Graaf, Tonia Hymers, Elizabeth Forsythe, Philip Beales   +16 more
wiley   +1 more source

Molecular changes induced in rat liver by hemorrhage and effects of melanocortin treatment.

, 2012
Melanocortin peptides improve hemodynamic parameters and prevent death during severe hemorrhagic shock. In the present research we determined influences of a synthetic melanocortin 1/4 receptor agonist on the molecular changes that occur in rat liver ...
Leonardi P., GRIECO, PAOLO, Carlin A., Catania A., Lonati C., Galantucci M., Giuliani D., Sordi A., Ottani A., Spaccapelo L., Guarini S.   +10 more
core   +1 more source

Coat Color‐Associated Transcriptomic Differences of Black and White Hortobágyi Racka Sheep Using the RNA‐Seq Technique

Ecology and Evolution, Volume 16, Issue 10, October 2026.
We compared skin transcriptomes of black‐ and white‐coated Hortobágyi Racka sheep using RNA‐seq to identify coat color‐associated molecular differences. Black‐coated sheep showed coordinated upregulation of melanogenesis and melanosome‐related genes together with pathways linked to redox balance, mitochondrial metabolism, and thermogenesis.
Putri Kusuma Astuti, Zoltán Bagi, Lilla Bodrogi, Szilvia Kusza   +3 more
wiley   +1 more source

Discovery of Novel Potent and Selective Agonists at the Melanocortin-3 Receptor

, 2015
The melanocortin receptors 3 and 4 control energy homeostasis, food-intake behavior, and correlated pathophysiological conditions. The melanocortin-4 receptor (MC4R) has been broadly investigated.
GRIECO, PAOLO, BRANCACCIO, DIEGO, CAROTENUTO, ALFONSO, MERLINO, FRANCESCO, NOVELLINO, ETTORE, Francesco Merlino (405661), Ali Munaim Yousif (734258), Minying Cai (1352319), YOUSIF, ALI MUNAIM, Ettore Novellino (333902), Diego Brancaccio (1451125), Alfonso Carotenuto (405657), Cai, Minying, Paolo Grieco (333900), Hruby, Victor J., Victor J. Hruby (1318077)   +15 more
core   +1 more source