Results 111 to 120 of about 67,182 (234)
The Journal of Poultry Science, 2010 The agouti signaling protein (ASIP)/melanocortin signaling system regulates lipid metabolism in humans but not in mice. To examine whether the system is present in adipose tissues in chickens, we performed reverse transcription-polymerase chain reaction
Masafumi Yabuuchi +4 more
doaj +1 more source
HIV Medicine, Volume 27, Issue 5, Page 727-739, May 2026.Abstract Introduction Long‐acting injectable antiretroviral therapy (ART) with Cabotegravir (CAB) and Rilpivirine (RPV) offers an alternative to daily oral regimens, improving adherence and patient satisfaction. However, its impact on body composition and metabolism remains underexplored.
Andrea De Vito +13 more
wiley +1 more source
Global consensus on the management of melanin hyperpigmentation disorders
Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 5, Page 760-772, May 2026.A global Delphi consensus of 10 dermatology experts established evidence‐based recommendations for melanin hyperpigmentation disorders, providing unified classification, photoprotection guidance and treatment algorithms. This framework harmonizes terminology and supports individualized management across diverse skin types and health systems.
Thierry Passeron +9 more
wiley +1 more source
Regulation of Lean Mass, Bone Mass, and Exercise Tolerance by the Central Melanocortin System [PDF]
, 2012 Signaling via the type 4-melanocortin receptor (MC4R) is an important determinant of body weight in mice and humans, where loss of function mutations lead to significant obesity.
Bouxsein, Mary Larsen +8 more
core +2 more sources
Frontiers in Immunology, 2019 To date, available treatment strategies for multiple sclerosis (MS) are ineffective in preventing or reversing progressive neurologic deterioration, creating a high, and unmet medical need. One potential way to fight MS may be by limiting the detrimental
Alwin Kamermans +8 more
doaj +1 more source
Epidemiology of diabetes mellitus among 193,435 cats attending primary-care veterinary practices in England [PDF]
, 2016 BACKGROUND: Diabetes mellitus (DM) is a common endocrine disease of cats. The prevalence of DM in cats in England is not well‐defined. HYPOTHESIS/OBJECTIVES: To estimate the prevalence and identify risk factors for DM in a large population of cats ...
Brodbelt, D C +6 more
core +1 more source
CNS Control of Glucose Metabolism: Response to Environmental Challenges [PDF]
, 2013 Over the last 15 years, considerable work has accumulated to support the role of the CNS in regulating postprandial glucose levels. As discussed in the first section of this review, the CNS receives and integrates information from afferent neurons ...
Arble, Deanna M., Sandoval, Darleen A.
core +1 more source
Defining Acquired Hypothalamic Obesity: An Expert Call for Unified Diagnosis and Therapeutic Action
Diabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 4437-4441, June 2026.
Hanneke M. van Santen +7 more
wiley +1 more source
Leptin is required for hypothalamic regulation of miRNAs targeting POMC 3’UTR
Frontiers in Cellular Neuroscience, 2015 The central nervous system monitors modifications in metabolic parameters or hormone levels and elicits adaptive responses such as food intake regulation. Particularly, within the hypothalamus, leptin modulates the activity of pro-opiomelanocortin (POMC)
Adel eDerghal +10 more
doaj +1 more source
Dual effects of leptin in perioperative gas exchange of morbidly obese patients [PDF]
, 2018 Leptin has shown positive effects on respiratory function in experimental settings. The role of leptin on perioperative respiratory function in morbidly obese patients has not been established.
Carron, Michele +6 more
core +2 more sources