Results 151 to 160 of about 47,532 (196)
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Archives of Dermatology, 2001
Although human pigmentation is genetically complex, to date polymorphism at only 1 locus, the melanocortin-1 receptor (MC1-R), has been associated with physiologic variation in hair and skin color. The MC1-R, a G protein-coupled receptor with 7 transmembrane-spanning domains, plays a key role in determining the type of melanin (eumelanin vs pheomelanin)
J V, Schaffer, J L, Bolognia
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Although human pigmentation is genetically complex, to date polymorphism at only 1 locus, the melanocortin-1 receptor (MC1-R), has been associated with physiologic variation in hair and skin color. The MC1-R, a G protein-coupled receptor with 7 transmembrane-spanning domains, plays a key role in determining the type of melanin (eumelanin vs pheomelanin)
J V, Schaffer, J L, Bolognia
openaire +2 more sources
Melanocortins in Brain Inflammation: The Role of Melanocortin Receptor Subtypes
2010The melanocortins (MC) are released from neurons and paracrine cells in the CNS where they are involved in important physiological functions, including regulation of body temperature and immune responses. MC bind to melanocortin receptors, a class of cell surface G-protein-coupled receptors. Of the five subtypes of MC receptors that have been cloned in
Ruta, Muceniece, Maija, Dambrova
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The physiological role of melanocortin receptors
2001Publisher Summary This chapter discusses that melanocortin research is expanding rapidly but our knowledge is inadequate in several aspects. The role of the MC1 receptor in inflammation is disputed and the potential role of other MC receptors is still unclear.
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Melanocortin-4 receptor mutations in obesity.
Advances in clinical chemistry, 2009The current alarming spread of obesity in many parts of the world is caused by a sudden environmental shift characterized by replacement of a frugal diet with low cost, energy dense food, and little requests for physical activity during work and leisure time.
SANTINI, FERRUCCIO +5 more
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Melanocortin-5 Receptor: Pharmacology and Its Regulation of Energy Metabolism
International Journal of Molecular Sciences, 2022Ya-Xiong Tao, Ye Hong, Tao Ya-Xiong
exaly
Characterisation of melanocortin receptor subtypes by radioligand binding analysis
European Journal of Pharmacology, 1995Helgi Schioth +2 more
exaly
Structural Complexity and Plasticity of Signaling Regulation at the Melanocortin-4 Receptor
International Journal of Molecular Sciences, 2020Patrick Scheerer +2 more
exaly
Involvement of the melanocortin MC4 receptor in stress-related behavior in rodents
European Journal of Pharmacology, 2003Shigeru Okuyama, Yoshihisa Toda
exaly