Selective Interactions of Mouse Melanocortin Receptor Accessory Proteins with Somatostatin Receptors. [PDF]
Cells, 2022 Wang M +6 more
europepmc +1 more source
When Macrocyclic Peptides Meet the Crystal Structure of a Melanocortin Receptor. [PDF]
J Med Chem, 2021 Grieco P.
europepmc +1 more source
Melanocortin receptor agonist NDP-α-MSH improves cognitive deficits and microgliosis but not amyloidosis in advanced stages of AD progression in 5XFAD and 3xTg mice. [PDF]
Front Immunol, 2022 Daini E +9 more
europepmc +1 more source
Identification of Regions Involved in the Physical Interaction between Melanocortin Receptor Accessory Protein 2 and Prokineticin Receptor 2. [PDF]
Biomolecules, 2022 Fullone MR +4 more
europepmc +1 more source
Fasting-induced activity changes in MC3R neurons of the paraventricular nucleus of the thalamus
Life Science AllianceThis study assesses how the brain responds to fasting and the role of melanocortin 3 receptor neurons within the paraventricular nucleus of the thalamus, measured using immunohistochemistry, microscopy, chemogenetics, and behavioral analysis.
Robert A Chesters +13 more
doaj +1 more source
Melanocortin receptor activation alleviates amyloid pathology and glial reactivity in an Alzheimer's disease transgenic mouse model. [PDF]
Sci Rep, 2021 Lau JKY +6 more
europepmc +1 more source
Discovery of a Pan-Melanocortin Receptor Antagonist [Ac-DPhe(pI)-Arg-Nal(2')-Orn-NH2] at the MC1R, MC3R, MC4R, and MC5R that Mediates an Increased Feeding Response in Mice and a 40-Fold Selective MC1R Antagonist [Ac-DPhe(pI)-DArg-Nal(2')-Arg-NH2]. [PDF]
J Med Chem, 2023 Ericson MD +8 more
europepmc +1 more source
PLoS BiologyThe hypothalamus is crucial for regulating essential bodily functions, including energy balance. It is an exceedingly complex and heterogeneous brain region that contains a variety of neuronal systems that are interconnected with each other. Among these,
Pierre-Yves Barelle +7 more
doaj +1 more source